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Index > Protein center > CDC26(Gene name) > Human
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  • CDC26 (Gene name),
  • Anaphase-promoting complex subunit CDC26 (Protein name ),  CDC26_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CDC26(ANAPC12;C9orf17);
    Protein name:
    Anaphase-promoting complex subunit CDC26;
    Alternative:
    Cell division cycle protein 26 homolog;Anaphase-promoting complex subunit 12(APC12);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    The APC/C is composed of at least 12 subunits.
    Function:
    Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    85
    Sequence:
    50:
    MLRRKPTRLE | LKLDDIEEFE | NIRKDLETRK | KQKEDVEVVG | GSDGEGAIGL | 
    85:
    SSDPKSREQM | INDRIGYKPQ | PKPNNRSSQF | GSLEF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    UniGene:
    String:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Anaphase-promoting complex subunit CDC26
    ELISA Kit for Human Anaphase-promoting complex subunit CDC26
    ELISA Kit for Human Anaphase-promoting complex subunit CDC26
    ELISA Kit for Human Anaphase-promoting complex subunit CDC26
    CLIA Kit for Human Anaphase-promoting complex subunit CDC26
    CLIA Kit for Human Anaphase-promoting complex subunit CDC26
    CLIA Kit for Human Anaphase-promoting complex subunit CDC26
    CLIA Kit for Human Anaphase-promoting complex subunit CDC26
    Polyclonal Antibody for Human Anaphase-promoting complex subunit CDC26
    Polyclonal Antibody for Human Anaphase-promoting complex subunit CDC26
    Polyclonal Antibody for Human Anaphase-promoting complex subunit CDC26
    Polyclonal Antibody for Human Anaphase-promoting complex subunit CDC26
    Monoclonal Antibody for Human Anaphase-promoting complex subunit CDC26
    Monoclonal Antibody for Human Anaphase-promoting complex subunit CDC26
    Monoclonal Antibody for Human Anaphase-promoting complex subunit CDC26
    Monoclonal Antibody for Human Anaphase-promoting complex subunit CDC26
    Protein for Human Anaphase-promoting complex subunit CDC26
    Protein for Human Anaphase-promoting complex subunit CDC26
    Protein for Human Anaphase-promoting complex subunit CDC26
    Protein for Human Anaphase-promoting complex subunit CDC26

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    Linearity
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    References
    1. 1.
      "The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex."
      Gmachl M. , Gieffers C. , Podtelejnikov A.V. , Mann M. , Peters J.-M.
      Proc. Natl. Acad. Sci. U.S.A.97:8973-8978(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];IDENTIFICATION IN THE APC/C COMPLEX
    2. 2.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
      tissue: Skin.
    4. 4.
      "Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex."
      Jin L. , Williamson A. , Banerjee S. , Philipp I. , Rape M.
      Cell133:653-665(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION OF THE APC/C
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-42;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    6. 6.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 7.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-42 AND SER-82;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 8.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-82;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C."
      Dube P. , Herzog F. , Gieffers C. , Sander B. , Riedel D. , Mueller S.A. , Engel A. , Peters J.-M. , Stark H.
      Mol. Cell20:867-879(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ELECTRON MICROSCOPY OF THE APC/C
    10. 10.
      "Insights into anaphase promoting complex TPR subdomain assembly from a CDC26-APC6 structure."
      Wang J. , Dye B.T. , Rajashankar K.R. , Kurinov I. , Schulman B.A.
      Nat. Struct. Mol. Biol.16:987-989(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 1-29 IN COMPLEX WITH CDC16
    11. 11.
      "Molecular architecture and mechanism of the anaphase-promoting complex."
      Chang L. , Zhang Z. , Yang J. , McLaughlin S.H. , Barford D.
      Nature513:388-393(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY ELECTRON MICROSCOPY (7.4 ANGSTROMS) OF THE APC/C;SUBUNIT
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