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Index > Protein center > Cep164(Gene name) > Mouse
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  • Cep164 (Gene name),
  • Centrosomal protein of 164 kDa (Protein name ),  CE164_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cep164(Kiaa1052);
    Protein name:
    Centrosomal protein of 164 kDa(Cep164);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts (via N-terminus) with ATRIP. Interacts with ATM, ATR and MDC1. Interacts with XPA (via N-terminus) upon UV irradiation.
    Function:
    Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHK2 and CHK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHK1.
    Subcellular Location:
    Cytoplasm cytoskeleton centrosome centriole Nucleus Localizes specifically to very distally located appendage structures on the mature centriole from which initiate PC formation. Persisted at centrioles throughout mitosis.
    Protein Attributes:
    Sequence length:
    1446
    Sequence:
    50:
    MARRPILLGD | QLVLEEDSDE | TYVPSEQEIL | DFARVIGIDP | IKEPELMWLA | 
    100:
    REGIEAPLPK | GWKPCQNITG | DLYYFNFDTG | QSIWDHPCDE | HYRKLVIQER | 
    150:
    ERWSAPGAIK | KKDKKKKKEK | KNKKDKETSK | SPLVLGSPLA | LVQAPLWGLA | 
    200:
    PLRGLGDAPP | SALRGSQSVS | LGSSADSGHL | GEPTLPPQGL | KAAACAKGLL | 
    250:
    ASVHEGKNAL | SLLTLGEETN | EEDEEESDNQ | SVRSSSELLK | NLHLDLGALG | 
    300:
    GNFEYEESPR | TSQPDKKDVS | LDSDADRPPT | PGKLFSQGAD | SSVASANGSK | 
    350:
    SQGRGASPWN | PQKENENSDP | KASSSQMAPE | LDPGGDQPSR | ASKKQQAEDP | 
    400:
    VQAGKEGECR | RESAAKEPKE | ASALENTSDV | SEESEIHGHL | KDARHSGSEA | 
    450:
    SGPKSFLGLD | LGFRSRISEH | LLDGDTLSPV | LGGGHWEAQG | LDQEEQDDSK | 
    500:
    SSIAEPQSKH | TQGSEREHLQ | SSLHSQATEE | GPLQTLEGQP | EWKEAEGPGK | 
    550:
    DSVASPAPLS | LLQREQVLSP | PASPERAEEK | HSQAEELGLE | QPEAEETEEK | 
    600:
    VAVCPSSPVS | PEVQTAEPAA | PQKLFSEAIL | KGMELEEDQR | LLLEFQKEKP | 
    650:
    QQLEERLWEE | EEEEVCQLYQ | QKEKSLSLLK | AQLQKATAEE | KEKEEETKIR | 
    700:
    EEESRRLVCL | RAQVQSRTEA | FENQIRTEQQ | AALQRLREEA | ETLQKAERAS | 
    750:
    LEQKSRRALE | QLREQLEAEE | RSAQAALRAE | KEAEKEAALL | QLREQLEGER | 
    800:
    KEAVAGLEKK | HSAELEQLCS | SLEAKHQEVI | SSLQKKIEGA | QQKEEAQLQE | 
    850:
    SLGWAEQRAH | QKVHQVTEYE | QELSSLLRDK | RQEVEREHER | KMDKMKEEHW | 
    900:
    QEMADARERY | EAEERKQRAD | LLGHLTGELE | RLRRAHEREL | ESMRQEQDQQ | 
    950:
    LEDLRRRHRD | HERKLQDLEV | ELSSRTKDVK | ARLAQLNVQE | ENIRKEKQLL | 
    1000:
    LDAQRQAALE | REEATATHQH | LEEAKKEHTH | LLETKQQLRR | TIDDLRVRRV | 
    1050:
    ELESQVDLLQ | AQSQRLQKHL | SSLEAEVQRK | QDVLKEMAAE | MNASPHPEPG | 
    1100:
    LHIEDLRKSL | DTNKNQEVSS | SLSLSKEEID | LSMESVRQFL | SAEGVAVRNA | 
    1150:
    KEFLVRQTRS | MRRRQTALKA | AQQHWRHELA | SAQEVDEDLP | GTEVLGNMRK | 
    1200:
    NLNEETRHLD | EMKSAMRKGH | DLLKKKEEKL | IQLESSLQEE | VSDEDTLKGS | 
    1250:
    SIKKVTFDLS | DMDDLSSESL | ESSPVLHITP | TPTSADPNKI | HYLSSSLQRI | 
    1300:
    SSELNGVLNV | LGSLNSQPPP | QGLGSQPPPP | LFTSSLRSSK | NVLDPAYSSQ | 
    1350:
    AKLSSLSSIT | PMSTQWAWDP | GQGTKLTSSS | SSQTVDDFLL | EKWRKYFPSG | 
    1400:
    IPLLSGSPPP | PENKLGYVSV | SEQLHFLQRS | HPRVPRTDGV | SIQSLIDSNR | 
    1446:
    KWLEHFRNDP | KVQLFSSAPK | ATTTSNLSNL | LQLGLDENNR | LNVFHY
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Cep164
    ELISA Kit for Mouse Cep164
    CLIA Kit for Mouse Cep164
    CLIA Kit for Mouse Cep164
    Polyclonal Antibody for Mouse Cep164
    Polyclonal Antibody for Mouse Cep164
    Monoclonal Antibody for Mouse Cep164
    Monoclonal Antibody for Mouse Cep164
    Protein for Mouse Cep164
    Protein for Mouse Cep164

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-114 (ISOFORMS 1/2/3);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 223-862 (ISOFORM 3);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1028-1446 (ISOFORM 2)
      strain: C57BL/6J.
      tissue: Embryo.
      tissue: Visual cortex.
      tissue: Wolffian duct.
    3. 3.
      "Prediction of the coding sequences of mouse homologues of KIAA gene. The complete nucleotide sequences of mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R.F. , Ohara R. , Inamoto S. , Nagase T. , Ohara O. , Koga H.
      Submitted (2005-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 158-1446 (ISOFORM 2)
      tissue: Fetal brain.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 909-1446 (ISOFORM 2)
      strain: C57BL/6J.
      tissue: Embryo.
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