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Index > Protein center > CECR1(Gene name) > Human
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  • CECR1 (Gene name),
  • Adenosine deaminase CECR1 (Protein name ),  CECR1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    CECR1(ADA2;ADGF;IDGFL);
    Protein name:
    Adenosine deaminase CECR1;
    Alternative:
    Cat eye syndrome critical region protein 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer. Interacts with adenosine receptors. Binds heparin.
    Function:
    Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    511
    Sequence:
    50:
    MLVDGPSERP | ALCFLLLAVA | MSFFGSALSI | DETRAHLLLK | EKMMRLGGRL | 
    100:
    VLNTKEELAN | ERLMTLKIAE | MKEAMRTLIF | PPSMHFFQAK | HLIERSQVFN | 
    150:
    ILRMMPKGAA | LHLHDIGIVT | MDWLVRNVTY | RPHCHICFTP | RGIMQFRFAH | 
    200:
    PTPRPSEKCS | KWILLEDYRK | RVQNVTEFDD | SLLRNFTLVT | QHPEVIYTNQ | 
    250:
    NVVWSKFETI | FFTISGLIHY | APVFRDYVFR | SMQEFYEDNV | LYMEIRARLL | 
    300:
    PVYELSGEHH | DEEWSVKTYQ | EVAQKFVETH | PEFIGIKIIY | SDHRSKDVAV | 
    350:
    IAESIRMAMG | LRIKFPTVVA | GFDLVGHEDT | GHSLHDYKEA | LMIPAKDGVK | 
    400:
    LPYFFHAGET | DWQGTSIDRN | ILDALMLNTT | RIGHGFALSK | HPAVRTYSWK | 
    450:
    KDIPIEVCPI | SNQVLKLVSD | LRNHPVATLM | ATGHPMVISS | DDPAMFGAKG | 
    500:
    LSYDFYEVFM | GIGGMKADLR | TLKQLAMNSI | KYSTLLESEK | NTFMEIWKKR | 
    511:
    WDKFIADVAT | K
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    MIM:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Adenosine deaminase CECR1
    Cat.:
    E1026h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Adenosine deaminase CECR1
    Cat.:
    E1026p
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Adenosine deaminase CECR1
    Cat.:
    U1026h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Adenosine deaminase CECR1
    Cat.:
    U1026p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Adenosine deaminase CECR1
    Polyclonal Antibody for Human Adenosine deaminase CECR1
    Cat.:
    P1026Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Adenosine deaminase CECR1
    Monoclonal Antibody for Human Adenosine deaminase CECR1
    Protein for Human Adenosine deaminase CECR1
    Protein for Human Adenosine deaminase CECR1

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-174 AND ASN-378
      tissue: Liver.
    2. 2.
      "Human adenosine deaminase 2 induces differentiation of monocytes into macrophages and stimulates proliferation of T helper cells and macrophages."
      Zavialov A.V. , Gracia E. , Glaichenhaus N. , Franco R. , Zavialov A.V. , Lauvau G.
      J. Leukoc. Biol.88:279-290(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;SUBCELLULAR LOCATION;HEPARIN-BINDING;SUBUNIT
    3. 3.
      "Structural basis for the growth factor activity of human adenosine deaminase ADA2."
      Zavialov A.V. , Yu X. , Spillmann D. , Lauvau G. , Zavialov A.V.
      J. Biol. Chem.285:12367-12377(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 29-511 IN COMPLEX WITH ZINC IONS AND TRANSITION STATE ANALOG COFORMYCIN;FUNCTION;COFACTOR;SUBCELLULAR LOCATION;SUBUNIT;DISULFIDE BOND;DOMAINS;GLYCOSAMINOCLYCAN BINDING;MUTAGENESIS OF CYS-137 AND TRP-362;GLYCOSYLATION AT ASN-127; ASN-185 AND ASN-378
    4. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PAN VAL-47; ARG-47; LEU-251 AND SER-264
    5. 6.
      "The human homolog of insect-derived growth factor, CECR1, is a candidate gene for features of cat eye syndrome."
      Riazi M.A. , Brinkman-Mills P. , Nguyen T. , Pan H. , Phan S. , Ying F. , Roe B.A. , Tochigi J. , Shimizu Y. , Minoshima S. , Shimizu N. , Buchwald M. , McDermid H.E.
      Genomics64:277-285(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT ARG-335
    6. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    7. 8.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);VARIANT ARG-335
      tissue: Thymus.
    8. 9.
      "The DNA sequence of human chromosome 22."
      Dunham I. , Hunt A.R. , Collins J.E. , Bruskiewich R. , Beare D.M. , Clamp M. , Smink L.J. , Ainscough R. , Almeida J.P. , Babbage A.K. , Bagguley C. , Bailey J. , Barlow K.F. , Bates K.N. , Beasley O.P. , Bird C.P. , Blakey S.E. , Bridgeman A.M. , more...
      Nature402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    10. 11.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    11. 12.
      "Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity."
      Zavialov A.V. , Engstroem A.
      Biochem. J.391:51-57(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES;TISSUE SPECIFICITY;IDENTIFICATION BY MASS SPECTROMETRY;HEPARIN-BINDING;SUBCELLULAR LOCATION
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