Gene name:
CELF3 (BRUNOL1;CAGH4;ERDA4;TNRC4) ;
Protein name:
CUGBP Elav-like family member 3 (CELF-3) ;
Alternative:
CAG repeat protein 4 ;Bruno-like protein 1 ;ELAV-type RNA-binding protein 1 (ETR-1) ;CUG-BP- and ETR-3-like factor 3 ;RNA-binding protein BRUNOL-1 ;Expanded repeat domain protein CAG/CTG 4 ;Trinucleotide repeat-containing gene 4 protein ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
Subcellular Location:
Nucleus
Cytoplasm
Protein Attributes:
50:
MKEPDAIKLF | VGQIPRHLEE | KDLKPIFEQF | GRIFELTVIK | DKYTGLHKGC |
100:
AFLTYCARDS | ALKAQSALHE | QKTLPGMNRP | IQVKPADSES | RGEDRKLFVG |
150:
MLGKQQTDED | VRKMFEPFGT | IDECTVLRGP | DGTSKGCAFV | KFQTHAEAQA |
200:
AINTLHSSRT | LPGASSSLVV | KFADTEKERG | LRRMQQVATQ | LGMFSPIALQ |
250:
FGAYSAYTQA | LMQQQAALVA | AHSAYLSPMA | TMAAVQMQHM | AAINANGLIA |
300:
TPITPSSGTS | TPPAIAATPV | SAIPAALGVN | GYSPVPTQPT | GQPAPDALYP |
350:
NGVHPYPAQS | PAAPVDPLQQ | AYAGMQHYTA | AYPAAYSLVA | PAFPQPPALV |
400:
AQQPPPPPQQ | QQQQQQQQQQ | QQQREGPDGC | NIFIYHLPQE | FTDSEILQMF |
450:
VPFGHVISAK | VFVDRATNQS | KCFGFVSFDN | PASAQAAIQA | MNGFQIGMKR |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Mouse
Human
ELISA Kit for Human CELF-3
ELISA Kit for Human CELF-3
ELISA Kit for Human CELF-3
CLIA Kit for Human CELF-3
CLIA Kit for Human CELF-3
CLIA Kit for Human CELF-3
Polyclonal Antibody for Human CELF-3
Polyclonal Antibody for Human CELF-3
Polyclonal Antibody for Human CELF-3
Monoclonal Antibody for Human CELF-3
Monoclonal Antibody for Human CELF-3
Monoclonal Antibody for Human CELF-3
R&D Technical Data
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Precision
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Recovery
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Linearity
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Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3)
tissue :
Brain .
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Retinoblastoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 109-465 (ISOFORM 1)
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Fetal brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 326-465
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 90-178