CELF5 ELISA Kit for Human(Homo sapiens) | EIAab.comCELF5 ELISA Kit for Human(Homo sapiens) | EIAab.com

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CELF5 (Gene name),

CUGBP Elav-like family member 5 (Protein name ), CELF5_HUMAN from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Gene name:

CELF5(BRUNOL5);

Protein name:

CUGBP Elav-like family member 5(CELF-5);

Alternative:

CUG-BP- and ETR-3-like factor 5;Bruno-like protein 5;RNA-binding protein BRUNOL-5;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.

Subcellular Location:

Nucleus Cytoplasm

Protein Attributes:

Sequence length:

485

Sequence:

50:

MARLTESEAR | RQQQQLLQPR | PSPVGSSGPE | PPGGQPDGMK | DLDAIKLFVG |

100:

QIPRHLDEKD | LKPLFEQFGR | IYELTVLKDP | YTGMHKGCAF | LTYCARDSAI |

150:

KAQTALHEQK | TLPGMARPIQ | VKPADSESRG | GRDRKLFVGM | LNKQQSEEDV |

200:

LRLFQPFGVI | DECTVLRGPD | GSSKGCAFVK | FSSHTEAQAA | IHALHGSQTM |

250:

PGASSSLVVK | FADTDKERTL | RRMQQMVGQL | GILTPSLTLP | FSPYSAYAQA |

300:

LMQQQTTVLS | TSGSYLSPGV | AFSPCHIQQI | GAVSLNGLPA | TPIAPASGLH |

350:

SPPLLGTTAV | PGLVAPITNG | FAGVVPFPGG | HPALETVYAN | GLVPYPAQSP |

400:

TVAETLHPAF | SGVQQYTAMY | PTAAITPIAH | SVPQPPPLLQ | QQQREGPEGC |

450:

NLFIYHLPQE | FGDTELTQMF | LPFGNIISSK | VFMDRATNQS | KCFGFVSFDN |

485:

PASAQAAIQA | MNGFQIGMKR | LKVQLKRPKD | PGHPY

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

MIM:

SMR:

KEGG:

UniGene:

Pfam:

Uniprot:

FOR

ELISA Kit for Human CELF-5

CLIA Kit for Human CELF-5

Polyclonal Antibody for Human CELF-5

Monoclonal Antibody for Human CELF-5

Protein for Human CELF-5

R&D Technical Data

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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References

1.

Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S. , Ohara O. , Nagase T. , Kikuno R.F.
Submitted (2005-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Brain.
2.

"The DNA sequence and biology of human chromosome 19."
Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT LEU-65
tissue: Brain.
5.

"The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing."
Ladd A.N. , Charlet-B N. , Cooper T.A.
Mol. Cell. Biol.21:1285-1296(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 1-482 (ISOFORM 1);FUNCTION;RNA-BINDING;TISSUE SPECIFICITY
tissue: Brain.
6.

"A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator."
Good P.J. , Chen Q. , Warner S.J. , Herring D.C.
J. Biol. Chem.275:28583-28592(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 396-478 (ISOFORM 1)
tissue: Brain.
7.

"Solution structure of RNA-binding domain in bruno-like 5 RNA-binding protein."
RIKEN structural genomics initiative (RSGI)
Submitted (2006-10) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 126-217

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