Gene name:
CENPI (FSHPRH1;ICEN19;LRPR1) ;
Protein name:
Centromere protein I (CENP-I) ;
Alternative:
Follicle-stimulating hormone primary response protein ;FSH primary response protein 1 ;Leucine-rich primary response protein 1 ;Interphase centromere complex protein 19 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Component of the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and CENPS. The CENPA-CAD complex interacts with the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and MLF1IP/CENPU. Interact with SENP6.
Function:
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone.
Subcellular Location:
Nucleus
Chromosome
centromere
Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Protein Attributes:
50:
MSPQKRVKNV | QAQNRTSQGS | SSFQTTLSAW | KVKQDPSNSK | NISKHGQNNP |
100:
VGDYEHADDQ | AEEDALQMAV | GYFEKGPIKA | SQNKDKTLEK | HLKTVENVAW |
150:
KNGLASEEID | ILLNIALSGK | FGNAVNTRIL | KCMIPATVIS | EDSVVKAVSW |
200:
LCVGKCSGST | KVLFYRWLVA | MFDFIDRKEQ | INLLYGFFFA | SLQDDALCPY |
250:
VCHLLYLLTK | KENVKPFRVR | KLLDLQAKMG | MQPHLQALLS | LYKFFAPALI |
300:
SVSLPVRKKI | YFKNSENLWK | TALLAVKQRN | RGPSPEPLKL | MLGPANVRPL |
350:
KRKWNSLSVI | PVLNSSSYTK | ECGKKEMSLS | DCLNRSGSFP | LEQLQSFPQL |
400:
LQNIHCLELP | SQMGSVLNNS | LLLHYINCVR | DEPVLLRFYY | WLSQTLQEEC |
450:
IWYKVNNYEH | GKEFTNFLDT | IIRAECFLQE | GFYSCEAFLY | KSLPLWDGLC |
500:
CRSQFLQLVS | WIPFSSFSEV | KPLLFDHLAQ | LFFTSTIYFK | CSVLQSLKEL |
550:
LQNWLLWLSM | DIHMKPVTNS | PLETTLGGSM | NSVSKLIHYV | GWLSTTAMRL |
600:
ESNNTFLLHF | ILDFYEKVCD | IYINYNLPLV | VLFPPGIFYS | ALLSLDTSIL |
650:
NQLCFIMHRY | RKNLTAAKKN | ELVQKTKSEF | NFSSKTYQEF | NHYLTSMVGC |
700:
LWTSKPFGKG | IYIDPEILEK | TGVAEYKNSL | NVVHHPSFLS | YAVSFLLQES |
750:
PEERTVNVSS | IRGKKWSWYL | DYLFSQGLQG | LKLFIRSSVH | HSSIPRAEGI |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Chicken
Human
Mouse
Rat
ELISA Kit for Human CENP-I
ELISA Kit for Human CENP-I
ELISA Kit for Human CENP-I
ELISA Kit for Human CENP-I
CLIA Kit for Human CENP-I
CLIA Kit for Human CENP-I
CLIA Kit for Human CENP-I
CLIA Kit for Human CENP-I
Polyclonal Antibody for Human CENP-I
Polyclonal Antibody for Human CENP-I
Polyclonal Antibody for Human CENP-I
Polyclonal Antibody for Human CENP-I
Monoclonal Antibody for Human CENP-I
Monoclonal Antibody for Human CENP-I
Monoclonal Antibody for Human CENP-I
Monoclonal Antibody for Human CENP-I
R&D Technical Data
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Precision
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Recovery
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Linearity
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Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Testis .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION
5.
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Genes Cells11:673-684(2006)
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN A COMPLEX WITH CENPH; CENPK; CENPN; CENPO; CENPP; CENPQ; CENPR AND CENPU;FUNCTION;SUBCELLULAR LOCATION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE CENPA-CAD COMPLEX WITH CENPK; CENPL; CENPO; CENPP; CENPQ; CENPR AND CENPS
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUMOYLATION;UBIQUITINATION BY RNF4;DESUMOYLATION BY SENP6;INTERACTION WITH SENP6