Gene name:
CENPL (C1orf155;ICEN33) ;
Protein name:
Centromere protein L (CENP-L) ;
Alternative:
Interphase centromere complex protein 33 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Component of the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and CENPS. The CENPA-CAD complex interacts with the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and MLF1IP/CENPU.
Function:
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.
Subcellular Location:
Nucleus
Chromosome
centromere
Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Protein Attributes:
50:
MDSYSAPEST | PSASSRPEDY | FIGATPLQKR | LESVRKQSSF | ILTPPRRKIP |
100:
QCSQLQEDVD | PQKVAFLLHK | QWTLYSLTPL | YKFSYSNLKE | YSRLLNAFIV |
150:
AEKQKGLAVE | VGEDFNIKVI | FSTLLGMKGT | QRDPEAFLVQ | IVSKSQLPSE |
200:
NREGKVLWTG | WFCCVFGDSL | LETVSEDFTC | LPLFLANGAE | SNTAIIGTWF |
250:
QKTFDCYFSP | LAINAFNLSW | MAAMWTACKM | DHYVATTEFL | WSVPCSPQSL |
300:
DISFAIHPED | AKALWDSVHK | TPGEVTQEEV | DLFMDCLYSH | FHRHFKIHLS |
344:
ATRLVRVSTS | VASAHTDGKI | KILCHKYLIG | VLAYLTELAI | FQIE
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
Chicken
Bovine
ELISA Kit for Human CENP-L
ELISA Kit for Human CENP-L
ELISA Kit for Human CENP-L
ELISA Kit for Human CENP-L
ELISA Kit for Human CENP-L
CLIA Kit for Human CENP-L
CLIA Kit for Human CENP-L
CLIA Kit for Human CENP-L
CLIA Kit for Human CENP-L
CLIA Kit for Human CENP-L
Polyclonal Antibody for Human CENP-L
Polyclonal Antibody for Human CENP-L
Polyclonal Antibody for Human CENP-L
Polyclonal Antibody for Human CENP-L
Polyclonal Antibody for Human CENP-L
Monoclonal Antibody for Human CENP-L
Monoclonal Antibody for Human CENP-L
Monoclonal Antibody for Human CENP-L
Monoclonal Antibody for Human CENP-L
Monoclonal Antibody for Human CENP-L
R&D Technical Data
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Precision
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Recovery
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Linearity
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Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
tissue :
Synovial cell .
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
Eye .
tissue :
Muscle .
tissue :
Urinary bladder .
4.
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Genes Cells11:673-684(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE CENPA-CAD COMPLEX WITH CENPI; CENPK; CENPO; CENPP; CENPQ; CENPR AND CENPS
6.
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Sci. Signal.3:RA3-RA3(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-53;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .