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Index > Protein center > CERS2(Gene name) > Human
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  • CERS2 (Gene name),
  • Ceramide synthase 2 (Protein name ),  CERS2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CERS2(LASS2;TMSG1);
    Protein name:
    Ceramide synthase 2(CerS2);
    Alternative:
    SP260;LAG1 longevity assurance homolog 2;Tumor metastasis-suppressor gene 1 protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with ATP6V0C, ASGR1, ASGR2 and SLC22A1/OCT1. Interacts with ELOV1, HSD17B12 and TECR.
    Function:
    Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis.
    Subcellular Location:
    Nucleus membrane Multi-pass membrane protein Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    380
    Sequence:
    50:
    MLQTLYDYFW | WERLWLPVNL | TWADLEDRDG | RVYAKASDLY | ITLPLALLFL | 
    100:
    IVRYFFELYV | ATPLAALLNI | KEKTRLRAPP | NATLEHFYLT | SGKQPKQVEV | 
    150:
    ELLSRQSGLS | GRQVERWFRR | RRNQDRPSLL | KKFREASWRF | TFYLIAFIAG | 
    200:
    MAVIVDKPWF | YDMKKVWEGY | PIQSTIPSQY | WYYMIELSFY | WSLLFSIASD | 
    250:
    VKRKDFKEQI | IHHVATIILI | SFSWFANYIR | AGTLIMALHD | SSDYLLESAK | 
    300:
    MFNYAGWKNT | CNNIFIVFAI | VFIITRLVIL | PFWILHCTLV | YPLELYPAFF | 
    350:
    GYYFFNSMMG | VLQLLHIFWA | YLILRMAHKF | ITGKLVEDER | SDREETESSE | 
    380:
    GEEAAAGGGA | KSRPLANGHP | ILNNNHRKND | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    SMR:
    Pfam:
    String:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human CerS2
    ELISA Kit for Human CerS2
    ELISA Kit for Human CerS2
    CLIA Kit for Human CerS2
    CLIA Kit for Human CerS2
    CLIA Kit for Human CerS2
    Polyclonal Antibody for Human CerS2
    Polyclonal Antibody for Human CerS2
    Polyclonal Antibody for Human CerS2
    Monoclonal Antibody for Human CerS2
    Monoclonal Antibody for Human CerS2
    Monoclonal Antibody for Human CerS2
    Protein for Human CerS2
    Protein for Human CerS2
    Protein for Human CerS2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1."
      Pan H. , Qin W.-X. , Huo K.-K. , Wan D.-F. , Yu Y. , Xu Z.-G. , Hu Q.-D. , Gu K.T. , Zhou X.-M. , Jiang H.-Q. , Zhang P.-P. , Huang Y. , Li Y.-Y. , Gu J.-R.
      Genomics77:58-64(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;INTERACTION WITH ATP6V0C; ASGR1; ASGR2 AND SLC22A1/OCT1
      tissue: Liver.
    2. 2.
      Qin W.-X. , Gu J.-R. , Wan D.-F. , Zhou X.-M. , Jiang H.-Q. , Zhang P.-P. , Huang Y. , Qiu X.-K. , Qian L.F. , He L.P. , Li H.N. , Yu Y. , Yu J.
      Submitted (2002-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    3. 3.
      Xingfeng C. , Yi G.
      Submitted (2002-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Kidney.
      tissue: Skin.
    7. 7.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 59-380
      tissue: Embryo.
    8. 8.
      "Cancer metastasis-related gene."
      Liu Y. , Zheng J. , Wu B. , Fang W.
      Submitted (2000-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 151-380
      tissue: Prostatic carcinoma.
    9. 9.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-341; THR-346; SER-348 AND SER-349;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach."
      Lewandrowski U. , Moebius J. , Walter U. , Sickmann A.
      Mol. Cell. Proteomics5:226-233(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-19
      tissue: Platelet.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-341; THR-346; SER-348 AND SER-349;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Platelet.
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    13. 13.
      "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
      Han G. , Ye M. , Zhou H. , Jiang X. , Feng S. , Jiang X. , Tian R. , Wan D. , Zou H. , Gu J.
      Proteomics8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-341; THR-346; SER-348 AND SER-349;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    14. 14.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-19
      tissue: Liver.
    15. 15.
      "ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis."
      Ohno Y. , Suto S. , Yamanaka M. , Mizutani Y. , Mitsutake S. , Igarashi Y. , Sassa T. , Kihara A.
      Proc. Natl. Acad. Sci. U.S.A.107:18439-18444(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ELOV1; HSD17B12 AND TECR
    16. 16.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-341;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    17. 17.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    18. 18.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-341; THR-346; SER-348 AND SER-349;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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