CHI3L1 ELISA Kit for Human(Homo sapiens) | EIAab.comCHI3L1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CHI3L1(Gene name) > Human

CHI3L1 (Gene name),

Chitinase-3-like protein 1 (Protein name ), CH3L1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CHI3L1;

Protein name:

Chitinase-3-like protein 1;

Alternative:

Cartilage glycoprotein 39(CGP-39;GP-39;hCGP-39);39 kDa synovial protein;YKL-40;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer.

Function:

Carbohydrate-binding lectin with a preference for chitin. May play a role in defense against pathogens, or in tissue remodeling. May play an important role in the capacity of cells to respond to and cope with changes in their environment.

Subcellular Location:

Secreted extracellular space

Protein Attributes:

Sequence length:

383

Sequence:

50:

100:

150:

200:

250:

300:

350:

383:

VWALDLDDFQ | GSFCGQDLRF | PLTNAIKDAL | AAT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00704

String:

P36222

UniGene:

Hs.382202

MIM:

601525

STRING:

9606.ENSP00000255409

SMR:

P36222

KEGG:

hsa:1116

Uniprot:

P36222

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ELISA Kit for Human Chitinase-3-like protein 1

Cat.:

E1463m

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96T

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ELISA Kit for Human Chitinase-3-like protein 1

Cat.:

E1463b

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96T

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ELISA Kit for Human Chitinase-3-like protein 1

Cat.:

E1463r

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ELISA Kit for Human Chitinase-3-like protein 1

Cat.:

E1463h

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ELISA Kit for Human Chitinase-3-like protein 1

Cat.:

E1463p

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96T

CLIA Kit for Human Chitinase-3-like protein 1

Cat.:

U1463h

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96T

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CLIA Kit for Human Chitinase-3-like protein 1

Cat.:

U1463p

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96T

CLIA Kit for Human Chitinase-3-like protein 1

Cat.:

U1463m

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96T

CLIA Kit for Human Chitinase-3-like protein 1

Cat.:

U1463r

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Packing:

96T

CLIA Kit for Human Chitinase-3-like protein 1

Cat.:

U1463b

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96T

Polyclonal Antibody for Human Chitinase-3-like protein 1

Cat.:

P1463Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Chitinase-3-like protein 1

Cat.:

P1463Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human Chitinase-3-like protein 1

Cat.:

P1463Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Chitinase-3-like protein 1

Monoclonal Antibody for Human Chitinase-3-like protein 1

Protein for Human Chitinase-3-like protein 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family."
Hakala B.E. , White C. , Recklies A.D.
J. Biol. Chem.268:25803-25810(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;VARIANT THR-311
tissue: Cartilage.
2.

"Molecular characterization of the gene for human cartilage gp-39 (CHI3L1), a member of the chitinase protein family and marker for late stages of macrophage differentiation."
Rehli M. , Krause S.W. , Andressen R.
Genomics43:221-225(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT THR-311
tissue: Blood.
3.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLY-145
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLY-145
tissue: Brain.
7.

"Human synovial cells secrete a 39 kDa protein similar to a bovine mammary protein expressed during the non-lactating period."
Nyirkos P. , Golds E.E.
Biochem. J.269:265-268(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 22-45
8.

"Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages."
Renkema G.H. , Boot R.G. , Au F.L. , Donker-Koopman W.E. , Strijland A. , Muijsers A.O. , Hrebicek M. , Aerts J.M.F.G.
Eur. J. Biochem.251:504-509(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF N-TERMINUS;FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
9.

"Chitinase 3-like-1 exacerbates intestinal inflammation by enhancing bacterial adhesion and invasion in colonic epithelial cells."
Mizoguchi E.
Gastroenterology130:398-411(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;INDUCTION
10.

"Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis."
Lee C.G. , Hartl D. , Lee G.R. , Koller B. , Matsuura H. , Da Silva C.A. , Sohn M.H. , Cohn L. , Homer R.J. , Kozhich A.A. , Humbles A. , Kearley J. , Coyle A. , Chupp G. , Reed J. , Flavell R.A. , Elias J.A.
J. Exp. Med.206:1149-1166(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
11.

"The chitinase-like proteins breast regression protein-39 and YKL-40 regulate hyperoxia-induced acute lung injury."
Sohn M.H. , Kang M.J. , Matsuura H. , Bhandari V. , Chen N.Y. , Lee C.G. , Elias J.A.
Am. J. Respir. Crit. Care Med.182:918-928(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION
12.

"Structure and ligand-induced conformational change of the 39-kDa glycoprotein from human articular chondrocytes."
Houston D.R. , Recklies A.D. , Krupa J.C. , van Aalten D.M.F.
J. Biol. Chem.278:30206-30212(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) OF 22-383 IN COMPLEX WITH CHITIN OLIGOMERS;DISULFIDE BONDS;GLYCOSYLATION AT ASN-60
13.

"Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39."
Fusetti F. , Pijning T. , Kalk K.H. , Bos E. , Dijkstra B.W.
J. Biol. Chem.278:37753-37760(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 22-383 IN COMPLEX WITH CHITIN OLIGOMERS;DISULFIDE BONDS
14.

"Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function."
Ober C. , Tan Z. , Sun Y. , Possick J.D. , Pan L. , Nicolae R. , Radford S. , Parry R.R. , Heinzmann A. , Deichmann K.A. , Lester L.A. , Gern J.E. , Lemanske R.F. Jr. , Nicolae D.L. , Elias J.A. , Chupp G.L.
N. Engl. J. Med.358:1682-1691(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN SUSCEPTIBILITY TO ASTHMA-RELATED TRAITS

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