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Index > Protein center > Chd4(Gene name) > Mouse
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  • Chd4 (Gene name),
  • Chromodomain-helicase-DNA-binding protein 4 (Protein name ),  CHD4_MOUSE from NCBI database.
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  • General Annotation
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  • Gene name:
    Chd4;
    Protein name:
    Chromodomain-helicase-DNA-binding protein 4(CHD-4);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Central component of the nucleosome remodeling and histone deacetylase (NuRD) repressor complex. Interacts with TRIM27. Interacts with ZGPAT; the interaction is direct. Part of a complex containing ATR and HDAC2. Interacts with PCNT (By similarity). Interacts with KLF1; the interaction depends on sumoylation of KLF1, and leads to its transcriptional repression. Interacts directly with IKFZ1 in the NuRD complex.
    Function:
    Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.
    Subcellular Location:
    Nucleus Cytoplasm cytoskeleton centrosome Associates with centrosomes in interphase.
    Protein Attributes:
    Sequence length:
    1915
    Sequence:
    50:
    MASGLGSPSP | CSAGSEEEDM | DALLNNSLPP | PHPENEEDPD | EDLSEAETPK | 
    100:
    LKKKKKPKKP | RDPKIPKSKR | QKKELGDSSG | EGPEFVEEEE | EVALRSDSEG | 
    150:
    SDYTPGKKKK | KKLGPKKEKK | SKSKRKEEEE | EEDEDDDSKE | PKSSAQLLED | 
    200:
    WGMEDIDHVF | SEEDYRTLTN | YKAFSQFVRP | LIAAKNPKIA | VSKMMMVLGA | 
    250:
    KWREFSTNNP | FKGSSGASVA | AAAAAAVAVV | ESMVTATEVA | PPPPPVEVPI | 
    300:
    RKAKTKEGKG | PNARRKPKGS | PRVPDAKKPK | PKKVAPLKIK | LGGFGSKRKR | 
    350:
    SSSEDDDLDV | ESDFDDASIN | SYSVSDGSTS | RSSRSRKKLR | TAKKKKKGEE | 
    400:
    EVTAVDGYET | DHQDYCEVCQ | QGGEIILCDT | CPRAYHMVCL | DPDMEKAPEG | 
    450:
    KWSCPHCEKE | GIQWEAKEDN | SEGEEILEEV | GGDPEEEDDH | HMEFCRVCKD | 
    500:
    GGELLCCDTC | PSSYHIHCLN | PPLPEIPNGE | WLCPRCTCPA | LKGKVQKILI | 
    550:
    WKWGQPPSPT | PVPRPPDADP | NTPSPKPLEG | RPERQFFVKW | QGMSYWHCSW | 
    600:
    VSELQLELHC | QVMFRNYQRK | NDMDEPPSGD | FGGDEEKSRK | RKNKDPKFAE | 
    650:
    MEERFYRYGI | KPEWMMIHRI | LNHSVDKKGH | VHYLIKWRDL | PYDQASWESE | 
    700:
    DVEIQDYDLF | KQSYWNHREL | MRGEEGRPGK | KLKKVKLRKL | ERPPETPTVD | 
    750:
    PTVKYERQPE | YLDATGGTLH | PYQMEGLNWL | RFSWAQGTDT | ILADEMGLGK | 
    800:
    TVQTAVFLYS | LYKEGHSKGP | FLVSAPLSTI | INWEREFEMW | APDMYVVTYV | 
    850:
    GDKDSRAIIR | ENEFSFEDNA | IRGGKKASRM | KKEASVKFHV | LLTSYELITI | 
    900:
    DMAILGSIDW | ACLIVDEAHR | LKNNQSKFFR | VLNGYSLQHK | LLLTGTPLQN | 
    950:
    NLEELFHLLN | FLTPERFHNL | EGFLEEFADI | AKEDQIKKLH | DMLGPHMLRR | 
    1000:
    LKADVFKNMP | SKTELIVRVE | LSPMQKKYYK | YILTRNFEAL | NARGGGNQVS | 
    1050:
    LLNVVMDLKK | CCNHPYLFPV | AAMEAPKMPN | GMYDGSALIR | ASGKLLLLQK | 
    1100:
    MLKNLKEGGH | RVLIFSQMTK | MLDLLEDFLE | HEGYKYERID | GGITGNMRQE | 
    1150:
    AIDRFNAPGA | QQFCFLLSTR | AGGLGINLAT | ADTVIIYDSD | WNPHNDIQAF | 
    1200:
    SRAHRIGQNK | KVMIYRFVTR | ASVEERITQV | AKKKMMLTHL | VVRPGLGSKT | 
    1250:
    GSMSKQELDD | ILKFGTEELF | KDEATDGGGD | NKEGEDSSVI | HYDDKAIERL | 
    1300:
    LDRNQDETED | TELQGMNEYL | SSFKVAQYVV | REEEMGEEEE | VEREIIKQEE | 
    1350:
    SVDPDYWEKL | LRHHYEQQQE | DLARNLGKGK | RIRKQVNYND | GSQEDRDWQD | 
    1400:
    DQSDNQSDYS | VASEEGDEDF | DERSEAPRRP | SRKGLRNDKD | KPLPPLLARV | 
    1450:
    GGNIEVLGFN | ARQRKAFLNA | IMRYGMPPQD | AFTTQWLVRD | LRGKSEKEFK | 
    1500:
    AYVSLFMRHL | CEPGADGAET | FADGVPREGL | SRQHVLTRIG | VMSLIRKKVQ | 
    1550:
    EFEHVNGRWS | MPELAEVEEN | KKMSQPGSPS | PKTPTPSTPG | DTQPNTPAPV | 
    1600:
    PPAEDGIKIE | ENSLKEEEST | EGEKEVKSTA | PEATVECAQP | PAPAPATAPA | 
    1650:
    TATAPEDDKA | PAEPPEGEEK | VEKAEVKERT | EEPMETEAKG | TTEVEKVEEK | 
    1700:
    SAVDLTPIVV | EDKEEKKEEE | EKKDVMLQNG | ETPKDLSDEK | QKKNSKQRFM | 
    1750:
    FNIADGGFTE | LHSLWQNEER | AATVTKKTYE | IWHRRHDYWL | LAGIINHGYA | 
    1800:
    RWQDIQNDPR | YAILNEPFKG | EMNRGNFLEI | KNKFLARRFK | LLEQALVIEE | 
    1850:
    QLRRAAYLNM | SEDPSHPSMA | LNTRFAEVEC | LAESHQHLSK | ESMAGNKPAN | 
    1900:
    AVLHKVLKQL | EELLSDMKAD | VTRLPATIAR | IPPVAVRLQM | SERNILSRLA | 
    1915:
    NRAPEPPPQQ | VAQQQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse CHD-4
    ELISA Kit for Mouse CHD-4
    CLIA Kit for Mouse CHD-4
    CLIA Kit for Mouse CHD-4
    Polyclonal Antibody for Mouse CHD-4
    Polyclonal Antibody for Mouse CHD-4
    Monoclonal Antibody for Mouse CHD-4
    Monoclonal Antibody for Mouse CHD-4
    Protein for Mouse CHD-4
    Protein for Mouse CHD-4

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Eye.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH IKFZ1 IN THE NURD COMPLEX
    3. 3.
      "Sumoylation of EKLF promotes transcriptional repression and is involved in inhibition of megakaryopoiesis."
      Siatecka M. , Xue L. , Bieker J.J.
      Mol. Cell. Biol.27:8547-8560(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KLF1;FUNCTION
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    5. 5.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-421 AND SER-1528;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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