Protein name:
Acidic mammalian chitinase (AMCase) ;
Alternative:
Lung-specific protein TSA1902 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with EGFR.
Function:
Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding.
Subcellular Location:
Isoform 3
Cytoplasm
Protein Attributes:
50:
MTKLILLTGL | VLILNLQLGS | AYQLTCYFTN | WAQYRPGLGR | FMPDNIDPCL |
100:
CTHLIYAFAG | RQNNEITTIE | WNDVTLYQAF | NGLKNKNSQL | KTLLAIGGWN |
150:
FGTAPFTAMV | STPENRQTFI | TSVIKFLRQY | EFDGLDFDWE | YPGSRGSPPQ |
200:
DKHLFTVLVQ | EMREAFEQEA | KQINKPRLMV | TAAVAAGISN | IQSGYEIPQL |
250:
SQYLDYIHVM | TYDLHGSWEG | YTGENSPLYK | YPTDTGSNAY | LNVDYVMNYW |
300:
KDNGAPAEKL | IVGFPTYGHN | FILSNPSNTG | IGAPTSGAGP | AGPYAKESGI |
350:
WAYYEICTFL | KNGATQGWDA | PQEVPYAYQG | NVWVGYDNIK | SFDIKAQWLK |
400:
HNKFGGAMVW | AIDLDDFTGT | FCNQGKFPLI | STLKKALGLQ | SASCTAPAQP |
450:
IEPITAAPSG | SGNGSGSSSS | GGSSGGSGFC | AVRANGLYPV | ANNRNAFWHC |
476:
VNGVTYQQNC | QAGLVFDTSC | DCCNWA
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
Bovine
ELISA Kit for Human AMCase
ELISA Kit for Human AMCase
ELISA Kit for Human AMCase
ELISA Kit for Human AMCase
CLIA Kit for Human AMCase
CLIA Kit for Human AMCase
CLIA Kit for Human AMCase
CLIA Kit for Human AMCase
Polyclonal Antibody for Human AMCase
Polyclonal Antibody for Human AMCase
Polyclonal Antibody for Human AMCase
Polyclonal Antibody for Human AMCase
Monoclonal Antibody for Human AMCase
Monoclonal Antibody for Human AMCase
Monoclonal Antibody for Human AMCase
Monoclonal Antibody for Human AMCase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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