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Index > Protein center > CHRD(Gene name) > Human
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  • CHRD (Gene name),
  • Chordin (Protein name ),  CHRD_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CHRD(UNQ217/PRO243);
    Protein name:
    Chordin;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with TWSG1 and/or BMP4.
    Function:
    Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    955
    Sequence:
    50:
    MPSLPAPPAP | LLLLGLLLLG | SRPARGAGPE | PPVLPIRSEK | EPLPVRGAAG | 
    100:
    CTFGGKVYAL | DETWHPDLGE | PFGVMRCVLC | ACEAPQWGRR | TRGPGRVSCK | 
    150:
    NIKPECPTPA | CGQPRQLPGH | CCQTCPQERS | SSERQPSGLS | FEYPRDPEHR | 
    200:
    SYSDRGEPGA | EERARGDGHT | DFVALLTGPR | SQAVARARVS | LLRSSLRFSI | 
    250:
    SYRRLDRPTR | IRFSDSNGSV | LFEHPAAPTQ | DGLVCGVWRA | VPRLSLRLLR | 
    300:
    AEQLHVALVT | LTHPSGEVWG | PLIRHRALAA | ETFSAILTLE | GPPQQGVGGI | 
    350:
    TLLTLSDTED | SLHFLLLFRG | LLEPRSGGLT | QVPLRLQILH | QGQLLRELQA | 
    400:
    NVSAQEPGFA | EVLPNLTVQE | MDWLVLGELQ | MALEWAGRPG | LRISGHIAAR | 
    450:
    KSCDVLQSVL | CGADALIPVQ | TGAAGSASLT | LLGNGSLIYQ | VQVVGTSSEV | 
    500:
    VAMTLETKPQ | RRDQRTVLCH | MAGLQPGGHT | AVGICPGLGA | RGAHMLLQNE | 
    550:
    LFLNVGTKDF | PDGELRGHVA | ALPYCGHSAR | HDTLPVPLAG | ALVLPPVKSQ | 
    600:
    AAGHAWLSLD | THCHLHYEVL | LAGLGGSEQG | TVTAHLLGPP | GTPGPRRLLK | 
    650:
    GFYGSEAQGV | VKDLEPELLR | HLAKGMASLM | ITTKGSPRGE | LRGQVHIANQ | 
    700:
    CEVGGLRLEA | AGAEGVRALG | APDTASAAPP | VVPGLPALAP | AKPGGPGRPR | 
    750:
    DPNTCFFEGQ | QRPHGARWAP | NYDPLCSLCT | CQRRTVICDP | VVCPPPSCPH | 
    800:
    PVQAPDQCCP | VCPEKQDVRD | LPGLPRSRDP | GEGCYFDGDR | SWRAAGTRWH | 
    850:
    PVVPPFGLIK | CAVCTCKGGT | GEVHCEKVQC | PRLACAQPVR | VNPTDCCKQC | 
    900:
    PVGSGAHPQL | GDPMQADGPR | GCRFAGQWFP | ESQSWHPSVP | PFGEMSCITC | 
    950:
    RCGAGVPHCE | RDDCSLPLSC | GSGKESRCCS | RCTAHRRPAP | ETRTDPELEK | 
    955:
    EAEGS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    String:
    KEGG:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Chordin
    ELISA Kit for Human Chordin
    ELISA Kit for Human Chordin
    CLIA Kit for Human Chordin
    CLIA Kit for Human Chordin
    CLIA Kit for Human Chordin
    Polyclonal Antibody for Human Chordin
    Polyclonal Antibody for Human Chordin
    Polyclonal Antibody for Human Chordin
    Monoclonal Antibody for Human Chordin
    Monoclonal Antibody for Human Chordin
    Monoclonal Antibody for Human Chordin
    Protein for Human Chordin
    Protein for Human Chordin
    Protein for Human Chordin

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "The human chordin gene encodes several differentially expressed spliced variants with distinct BMP opposing activities."
      Millet C. , Lemaire P. , Orsetti B. , Guglielmi P. , Francois V.
      Mech. Dev.106:85-96(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4);VARIANT LEU-630
    2. 2.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    4. 4.
      "Coding sequence and expression patterns of mouse chordin and mapping of the cognate mouse chrd and human CHRD genes."
      Pappano W.N. , Scott I.C. , Clark T.G. , Eddy R.L. , Shows T.B. , Greenspan D.S.
      Genomics52:236-239(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 115-955 (ISOFORM 5);VARIANT LEU-630
    5. 5.
      "BMP-binding modules in chordin: a model for signalling regulation in the extracellular space."
      Larrain J. , Bachiller D. , Lu B. , Agius E. , Piccolo S. , De Robertis E.M.
      Development127:821-830(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 51-125; 705-762; 784-850 AND 872-932
    6. 6.
      "An unappreciated role for RNA surveillance."
      Hillman R.T. , Green R.E. , Brenner S.E.
      Genome Biol.5:R8.1-R8.16(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SPLICE ISOFORM(S) THAT ARE POTENTIAL NMD TARGET(S)
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