CHST1 ELISA Kit for Human(Homo sapiens) | EIAab.comCHST1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CHST1(Gene name) > Human

CHST1 (Gene name),

Carbohydrate sulfotransferase 1 (Protein name ), CHST1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CHST1;

Protein name:

Carbohydrate sulfotransferase 1;

Alternative:

Keratan sulfate Gal-6 sulfotransferase(KS6ST;KSGal6ST;KSST);Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1(GST-1);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Catalyzes the transfer of sulfate to position 6 of galactose (Gal) residues of keratan. Has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal Gal residues are sulfated. May function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins. Participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation.

Subcellular Location:

Golgi apparatus membrane Single-pass type II membrane protein

Protein Attributes:

Sequence length:

411

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

411:

LVEERDFRPF | S

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000309270

UniGene:

Hs.104576

Pfam:

PF00685

String:

O43916

KEGG:

hsa:8534

MIM:

603797

SMR:

O43916

Uniprot:

O43916

FOR

ELISA Kit for Human Carbohydrate sulfotransferase 1

CLIA Kit for Human Carbohydrate sulfotransferase 1

Polyclonal Antibody for Human Carbohydrate sulfotransferase 1

Monoclonal Antibody for Human Carbohydrate sulfotransferase 1

Protein for Human Carbohydrate sulfotransferase 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning and characterization of human keratan sulfate Gal-6-sulfotransferase."
Fukuta M. , Inazawa J. , Torii T. , Tsuzuki K. , Shimada E. , Habuchi O.
J. Biol. Chem.272:32321-32328(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CATALYTIC ACTIVITY;TISSUE SPECIFICITY
tissue: Fetal brain.
2.

"Human chondroitin 6-sulfotransferase: cloning, gene structure, and chromosomal localization."
Mazany K.D. , Peng T. , Watson C.E. , Tabas I. , Williams K.J.
Biochim. Biophys. Acta1407:92-97(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"CHST1 and CHST2 sulfotransferases expressed by human vascular endothelial cells: cDNA cloning, expression, and chromosomal localization."
Li X. , Tedder T.F.
Genomics55:345-347(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Umbilical vein endothelial cell.
4.

NIEHS SNPs program
Submitted (2003-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
7.

"Sulfation of sialyl N-acetyllactosamine oligosaccharides and fetuin oligosaccharides by keratan sulfate Gal-6-sulfotransferase."
Torii T. , Fukuta M. , Habuchi O.
Glycobiology10:203-211(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBSTRATE SPECIFICITY;FUNCTION
8.

"Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin."
Bistrup A. , Bhakta S. , Lee J.K. , Belov Y.Y. , Gunn M.D. , Zuo F.-R. , Huang C.-C. , Kannagi R. , Rosen S.D. , Hemmerich S.
J. Cell Biol.145:899-910(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
9.

"CHST1 and CHST2 sulfotransferase expression by vascular endothelial cells regulates shear-resistant leukocyte rolling via L-selectin."
Li X. , Tu L. , Murphy P.G. , Kadono T. , Steeber D.A. , Tedder T.F.
J. Leukoc. Biol.69:565-574(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY

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