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Index > Protein center > CHST11(Gene name) > Human
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  • CHST11 (Gene name),
  • Carbohydrate sulfotransferase 11 (Protein name ),  CHSTB_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    CHST11;
    Protein name:
    Carbohydrate sulfotransferase 11;
    Alternative:
    Chondroitin 4-sulfotransferase 1(C4S-1;C4ST-1;C4ST1);Chondroitin 4-O-sulfotransferase 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
    Subcellular Location:
    Golgi apparatus membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    352
    Sequence:
    50:
    MKPALLEVMR | MNRICRMVLA | TCLGSFILVI | FYFQSMLHPV | MRRNPFGVDI | 
    100:
    CCRKGSRSPL | QELYNPIQLE | LSNTAVLHQM | RRDQVTDTCR | ANSATSRKRR | 
    150:
    VLTPNDLKHL | VVDEDHELIY | CYVPKVACTN | WKRLMMVLTG | RGKYSDPMEI | 
    200:
    PANEAHVSAN | LKTLNQYSIP | EINHRLKSYM | KFLFVREPFE | RLVSAYRNKF | 
    250:
    TQKYNISFHK | RYGTKIIKRQ | RKNATQEALR | KGDDVKFEEF | VAYLIDPHTQ | 
    300:
    REEPFNEHWQ | TVYSLCHPCH | IHYDLVGKYE | TLEEDSNYVL | QLAGVGSYLK | 
    350:
    FPTYAKSTRT | TDEMTTEFFQ | NISSEHQTQL | YEVYKLDFLM | FNYSVPSYLK | 
    352:
    LE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    MIM:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Carbohydrate sulfotransferase 11
    ELISA Kit for Human Carbohydrate sulfotransferase 11
    ELISA Kit for Human Carbohydrate sulfotransferase 11
    CLIA Kit for Human Carbohydrate sulfotransferase 11
    CLIA Kit for Human Carbohydrate sulfotransferase 11
    CLIA Kit for Human Carbohydrate sulfotransferase 11
    Polyclonal Antibody for Human Carbohydrate sulfotransferase 11
    Polyclonal Antibody for Human Carbohydrate sulfotransferase 11
    Polyclonal Antibody for Human Carbohydrate sulfotransferase 11
    Monoclonal Antibody for Human Carbohydrate sulfotransferase 11
    Monoclonal Antibody for Human Carbohydrate sulfotransferase 11
    Monoclonal Antibody for Human Carbohydrate sulfotransferase 11
    Protein for Human Carbohydrate sulfotransferase 11
    Protein for Human Carbohydrate sulfotransferase 11
    Protein for Human Carbohydrate sulfotransferase 11

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning, expression, and chromosomal mapping of human chondroitin 4-sulfotransferase, whose expression pattern in human tissues is different from that of chondroitin 6-sulfotransferase."
      Okuda T. , Mita S. , Yamauchi S. , Matsubara T. , Yagi F. , Yamamori D. , Fukuta M. , Kuroiwa A. , Matsuda Y. , Habuchi O.
      J. Biochem.128:763-770(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);ENZYME ACTIVITY;TISSUE SPECIFICITY
      tissue: Fetal brain.
    2. 2.
      "Molecular cloning and expression of two distinct human chondroitin 4-O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family."
      Hiraoka N. , Nakagawa H. , Ong E. , Akama O.T. , Fukuda N.M. , Fukuda M.
      J. Biol. Chem.275:20188-20196(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);ENZYME ACTIVITY;TISSUE SPECIFICITY
    3. 3.
      "Cloning and expression of a human chondroitin-4-sulfotransferase similar to members of the HNK-1 sulfotransferase family."
      Xia G. , Evers M.R. , Schachner M.
      Submitted (2000-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Lung.
    7. 7.
      "Specificities of three distinct human chondroitin/dermatan N-acetylgalactosamine 4-O-sulfotransferases demonstrated using partially desulfated dermatan sulfate as an acceptor. Implication of differential roles in dermatan sulfate biosynthesis."
      Mikami T. , Mizumoto S. , Kago N. , Kitagawa H. , Sugahara K.
      J. Biol. Chem.278:36115-36127(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBSTRATE SPECIFICITY
    8. 8.
      "Deregulation of the carbohydrate (chondroitin 4) sulfotransferase 11 (CHST11) gene in a B-cell chronic lymphocytic leukemia with a t(12;14)(q23;q32)."
      Schmidt H.H. , Dyomin V.G. , Palanisamy N. , Itoyama T. , Nanjangud G. , Pirc-Danoewinata H. , Haas O.A. , Chaganti R.S.K.
      Oncogene23:6991-6996(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISEASE;CHROMOSOMAL TRANSLOCATION WITH IGH
    9. 9.
      "N-linked oligosaccharides are required to produce and stabilize the active form of chondroitin 4-sulphotransferase-1."
      Yusa A. , Kitajima K. , Habuchi O.
      Biochem. J.388:115-121(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: BIOPHYSICOCHEMICAL PROPERTIES;GLYCOSYLATION;MUTAGENESIS OF LYS-125; ASN-205; ASN-223 AND ASN-342
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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