Gene name:
Chst15 (Galnac4s6st) ;
Protein name:
Carbohydrate sulfotransferase 15 ;
Alternative:
N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (GalNAc4S-6ST) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Homodimer; disulfide-linked (Potential). The relevance of homodimerization is however unsure. May interact with phosphorylated proteins in resting B-cells, including HCK.
Function:
Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.
Subcellular Location:
Golgi apparatus membrane
Single-pass type II membrane protein
A small fraction may also be present at the cell surface, where it acts as a B-cell receptor.
Protein Attributes:
50:
MRHCINCCIQ | LFPEDAHKQQ | VACQGGPHHS | HQACPSCKGE | DKILFRVDSK |
100:
QMNLLAVLEV | RTEGNENWGG | FLRFRKGKRC | SLVFGLIIMT | LVMASYILSG |
150:
AHQELLISSP | FHYGGFPSNP | SVMDSESPSD | VKEHHYQPSV | NNISYVKDYP |
200:
NIKLIIDSIA | ARNEFTTRQL | PDLQDLKRQE | LHMFSVIPNK | FLPTSKSPCW |
250:
YEEFSGRNTT | DPYLTNSYVL | YSKRFRSTFD | TLRKAFWGHL | SHVHGKHFRL |
300:
RCLPHFYIIG | QPKCGTTDLY | DRLRLHPEVK | FSAIKEPHWW | TRKRFGIVRL |
350:
RDGLRDRYPV | EDYLDLFDLA | AHQIHQGLQA | ASAEQTSKMN | RIIIGEASAS |
400:
TMWDNNAWTF | FYDNSTDGEP | PFLTQDFIHA | FQPEAKLLVM | LRDPVERLYS |
450:
DYLYFASSNK | SADDFHEKVT | EALQLFENCM | LDYSLRACVY | NNTLNNAMPV |
500:
RLQVGLYAVY | LLDWLTVFSK | EQFLILRLED | HASNVKYTMH | KVFQFLNLGP |
550:
LSEKQEALMT | KSPASNTRRP | EDRSLGPMWP | ITQKILRDFY | GPFNTRLAQV |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat Carbohydrate sulfotransferase 15
ELISA Kit for Rat Carbohydrate sulfotransferase 15
ELISA Kit for Rat Carbohydrate sulfotransferase 15
CLIA Kit for Rat Carbohydrate sulfotransferase 15
CLIA Kit for Rat Carbohydrate sulfotransferase 15
CLIA Kit for Rat Carbohydrate sulfotransferase 15
Polyclonal Antibody for Rat Carbohydrate sulfotransferase 15
Polyclonal Antibody for Rat Carbohydrate sulfotransferase 15
Polyclonal Antibody for Rat Carbohydrate sulfotransferase 15
Monoclonal Antibody for Rat Carbohydrate sulfotransferase 15
Monoclonal Antibody for Rat Carbohydrate sulfotransferase 15
Monoclonal Antibody for Rat Carbohydrate sulfotransferase 15
Protein for Rat Carbohydrate sulfotransferase 15
Protein for Rat Carbohydrate sulfotransferase 15
Protein for Rat Carbohydrate sulfotransferase 15
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Heart .