CIB1 ELISA Kit for Human(Homo sapiens) | EIAab.comCIB1 ELISA Kit for Human(Homo sapiens)

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CIB1 (Gene name),

Calcium and integrin-binding protein 1 (Protein name ), CIB1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

CIB1(CIB;KIP;PRKDCIP);

Protein name:

Calcium and integrin-binding protein 1(CIB);

Alternative:

Calmyrin;Calcium- and integrin-binding protein(CIBP);Kinase-interacting protein(KIP);DNA-PKcs-interacting protein;SNK-interacting protein 2-28(SIP2-28);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer. Interacts with the heterodimeric integrin alpha-IIb/beta3. Interacts with the protein kinases PLK2/SNK and with the region immediately upstream of the kinase domain of DNA-PK. Interacts with PSEN2. Interacts with MYO1C (By similarity). Interacts (via C-terminus) with F8. Interacts with NBR1 (via C-terminus). Interacts with FEZ1 (via C-terminus). Interacts with UBR5 (via C-terminus); the interaction is sensitive to DNA damage, and may target CIB1 for ubiquitin-mediated degradation. Interacts with IFI6. Interacts with BCL2. Interacts with TAS1R2 (via C-terminus); this interaction is independent of the myristoylation state of CIB1. Interacts with ITPR3; in a calcium dependent manner. Interacts with PTK2. Interacts with MAP3K5; inhibiting MAP3K5 activation by phosphorylation, and its subsequent interaction with TRAF2.

Function:

May convert the inactive conformation of integrin alpha-IIb/beta3 to an active form through binding to the integrin cytoplasmic domain. Induces cell migration and spreading mediated through integrin (possibly via focal adhesion complexes). Functions as a negative regulator of stress activated MAP kinase (MAPK) signaling pathways. May play a role in regulation of apoptosis. Interacts with and up-regulates PTK2 activity. Down regulates inositol 1,4,5-trisphosphate receptor-dependent calcium signaling.

Subcellular Location:

Membrane Lipid-anchor Cytoplasm Nucleus Cell projection filopodium Apical cell membrane Localizes to the perinuclear region in the presence of NBR1. Colocalizes with TAS1R2 in apical regions of taste receptor cells.

Protein Attributes:

Sequence length:

191

Sequence:

50:

100:

150:

191:

QLIDNILEES | DIDRDGTINL | SEFQHVISRS | PDFASSFKIV | L

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

602293

KEGG:

hsa:10519

String:

Q99828

STRING:

9606.ENSP00000333873

Pfam:

PF13499

UniGene:

Hs.715556

SMR:

Q99828

Uniprot:

Q99828

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ELISA Kit for Human CIB

Cat.:

E1394h

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96T

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ELISA Kit for Human CIB

Cat.:

E1394b

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96T

ELISA Kit for Human CIB

Cat.:

E1394m

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96T

ELISA Kit for Human CIB

Cat.:

E1394r

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96T

CLIA Kit for Human CIB

Cat.:

U1394r

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Packing:

96T

CLIA Kit for Human CIB

Cat.:

U1394m

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Packing:

96T

CLIA Kit for Human CIB

Cat.:

U1394h

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96T

CLIA Kit for Human CIB

Cat.:

U1394b

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96T

Polyclonal Antibody for Human CIB

Cat.:

P1394Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human CIB

Cat.:

P1394Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human CIB

Cat.:

P1394Rb-m

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40ug/0.2ml

Monoclonal Antibody for Human CIB

Protein for Human CIB

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain."
Naik U.P. , Patel P.M. , Parise L.V.
J. Biol. Chem.272:4651-4654(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH ITGA2B;TISSUE SPECIFICITY;CALCIUM-BINDING
tissue: Fetal liver.
2.

"Interaction between DNA-dependent protein kinase and a novel protein, KIP."
Wu X. , Lieber M.R.
Mutat. Res.385:13-20(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH PRKDC;TISSUE SPECIFICITY;VARIANT THR-44
3.

"Genomic structure of mouse and human genes for DNA-PKcs interacting protein (KIP)."
Hattori A. , Seki N. , Hayashi A. , Kozuma S. , Saito T.
DNA Seq.10:415-418(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT THR-44
4.

"A novel splice variant of calcium and integrin-binding protein 1 mediates protein kinase D2-stimulated tumour growth by regulating angiogenesis."
Armacki M. , Joodi G. , Nimmagadda S.C. , de Kimpe L. , Pusapati G.V. , Vandoninck S. , Van Lint J. , Illing A. , Seufferlein T.
Oncogene33:1167-1180(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION (ISOFORM 2);INTERACTION WITH PRKD2; PTK2 AND PAK1;SUBCELLULAR LOCATION (ISOFORM 2);TISSUE SPECIFICITY;PHOSPHORYLATION AT SER-78;MUTAGENESIS OF SER-78 AND THR-167
tissue: Brain.
5.

"SNK, a Ser/Thr protein kinase, associated proteins."
Yuan O.
Submitted (1997-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT THR-44
6.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
7.

"Human protein factory for converting the transcriptome into an in vitro-expressed proteome."
Goshima N. , Kawamura Y. , Fukumoto A. , Miura A. , Honma R. , Satoh R. , Wakamatsu A. , Yamamoto J. , Kimura K. , Nishikawa T. , Andoh T. , Iida Y. , Ishikawa K. , Ito E. , Kagawa N. , Kaminaga C. , Kanehori K. , Kawakami B. , more...
Nat. Methods5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
8.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Cervix.
10.

"Calcium-dependent properties of CIB binding to the integrin alphaIIb cytoplasmic domain and translocation to the platelet cytoskeleton."
Shock D.D. , Naik U.P. , Brittain J.E. , Alahari S.K. , Sondek J. , Parise L.V.
Biochem. J.342:729-735(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ITGA2B;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
11.

"A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein."
Stabler S.M. , Ostrowski L.L. , Janicki S.M. , Monteiro M.J.
J. Cell Biol.145:1277-1292(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MYRISTOYLATION AT GLY-2;INTERACTION WITH PSEN2
12.

"The interaction of the calcium- and integrin-binding protein (CIBP) with the coagulation factor VIII."
Fang X. , Chen C. , Wang Q. , Gu J. , Chi C.
Thromb. Res.102:177-185(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH F8
13.

"NBR1 interacts with fasciculation and elongation protein zeta-1 (FEZ1) and calcium and integrin binding protein (CIB) and shows developmentally restricted expression in the neural tube."
Whitehouse C. , Chambers J. , Howe K. , Cobourne M. , Sharpe P. , Solomon E.
Eur. J. Biochem.269:538-545(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NBR1 AND FEZ1;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
14.

"The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreading."
Haataja L. , Kaartinen V. , Groffen J. , Heisterkamp N.
J. Biol. Chem.277:8321-8328(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH RAC3;SUBCELLULAR LOCATION
15.

"EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response."
Henderson M.J. , Russell A.J. , Hird S. , Munoz M. , Clancy J.L. , Lehrbach G.M. , Calanni S.T. , Jans D.A. , Sutherland R.L. , Watts C.K.
J. Biol. Chem.277:26468-26478(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH UBR5
16.

"Molecular basis of CIB binding to the integrin alpha IIb cytoplasmic domain."
Barry W.T. , Boudignon-Proudhon C. , Shock D.D. , McFadden A. , Weiss J.M. , Sondek J. , Parise L.V.
J. Biol. Chem.277:28877-28883(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ITGA2B;SUBCELLULAR LOCATION;MUTAGENESIS OF PHE-115; LEU-131; ILE-153 AND PHE-173
17.

"Association of CIB with GPIIb/IIIa during outside-in signaling is required for platelet spreading on fibrinogen."
Naik U.P. , Naik M.U.
Blood102:1355-1362(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
18.

"Metal ion binding properties and conformational states of calcium- and integrin-binding protein."
Yamniuk A.P. , Nguyen L.T. , Hoang T.T. , Vogel H.J.
Biochemistry43:2558-2568(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ITGA2B;CALCIUM-BINDING;MAGNESIUM-BINDING
19.

"Calcium binding sequences in calmyrin regulates interaction with presenilin-2."
Zhu J. , Stabler S.M. , Ames J.B. , Baskakov I. , Monteiro M.J.
Exp. Cell Res.300:440-454(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH PSEN2;MUTAGENESIS OF ASP-127 AND GLU-172
20.

"Calcium-and integrin-binding protein regulates focal adhesion kinase activity during platelet spreading on immobilized fibrinogen."
Naik M.U. , Naik U.P.
Blood102:3629-3636(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH PTK2/FAK1
21.

"Calcium-binding calmyrin forms stable covalent dimers in vitro, but in vivo is found in monomeric form."
Sobczak A. , Blazejczyk M. , Piszczek G. , Zhao G. , Kuznicki J. , Wojda U.
Acta Biochim. Pol.52:469-476(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
22.

"G1P3, an interferon inducible gene 6-16, is expressed in gastric cancers and inhibits mitochondrial-mediated apoptosis in gastric cancer cell line TMK-1 cell."
Tahara E. Jr. , Tahara H. , Kanno M. , Naka K. , Takeda Y. , Matsuzaki T. , Yamazaki R. , Ishihara H. , Yasui W. , Barrett J.C. , Ide T. , Tahara E.
Cancer Immunol. Immunother.54:729-740(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH IFI6 AND BCL2
23.

"Essential role of CIB1 in regulating PAK1 activation and cell migration."
Leisner T.M. , Liu M. , Jaffer Z.M. , Chernoff J. , Parise L.V.
J. Cell Biol.170:465-476(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PAK1
24.

"Calcium- and magnesium-dependent interactions between calcium- and integrin-binding protein and the integrin alphaIIb cytoplasmic domain."
Yamniuk A.P. , Vogel H.J.
Protein Sci.14:1429-1437(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ITGA2B;CALCIUM-BINDING;MAGNESIUM-BINDING
25.

"CIB1, a ubiquitously expressed Ca2+-binding protein ligand of the InsP3 receptor Ca2+ release channel."
White C. , Yang J. , Monteiro M.J. , Foskett J.K.
J. Biol. Chem.281:20825-20833(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ITPR3
26.

"CIB1 is an endogenous inhibitor of agonist-induced integrin alphaIIbbeta3 activation."
Yuan W. , Leisner T.M. , McFadden A.W. , Wang Z. , Larson M.K. , Clark S. , Boudignon-Proudhon C. , Lam S.C. , Parise L.V.
J. Cell Biol.172:169-175(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PAK1;SUBCELLULAR LOCATION;MUTAGENESIS OF PHE-173
27.

"Sweet taste receptor interacting protein CIB1 is a general inhibitor of InsP3-dependent Ca2+ release in vivo."
Hennigs J.K. , Burhenne N. , Staehler F. , Winnig M. , Walter B. , Meyerhof W. , Schmale H.
J. Neurochem.106:2249-2262(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH TAS1R2;SUBCELLULAR LOCATION
28.

"CIB1 functions as a Ca(2+)-sensitive modulator of stress-induced signaling by targeting ASK1."
Yoon K.W. , Cho J.H. , Lee J.K. , Kang Y.H. , Chae J.S. , Kim Y.M. , Kim J. , Kim E.K. , Kim S.E. , Baik J.H. , Naik U.P. , Cho S.G. , Choi E.J.
Proc. Natl. Acad. Sci. U.S.A.106:17389-17394(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH MAP3K5
29.

"Auxiliary Ca2+ binding sites can influence the structure of CIB1."
Yamniuk A.P. , Anderson K.L. , Fraser M.E. , Vogel H.J.
Protein Sci.18:1128-1134(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;CALCIUM-BINDING
30.

"Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1."
Jarman K.E. , Moretti P.A. , Zebol J.R. , Pitson S.M.
J. Biol. Chem.285:483-492(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SPHK1;SUBCELLULAR LOCATION;MUTAGENESIS OF GLY-2
31.

"CIB1 is a regulator of pathological cardiac hypertrophy."
Heineke J. , Auger-Messier M. , Correll R.N. , Xu J. , Benard M.J. , Yuan W. , Drexler H. , Parise L.V. , Molkentin J.D.
Nat. Med.16:872-879(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
32.

"Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth."
Sobczak A. , Debowska K. , Blazejczyk M. , Kreutz M.R. , Kuznicki J. , Wojda U.
Biochim. Biophys. Acta1813:1025-1037(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH STMN2;SUBCELLULAR LOCATION
33.

"Calcium- and integrin-binding protein 1 regulates microtubule organization and centrosome segregation through polo like kinase 3 during cell cycle progression."
Naik M.U. , Naik U.P.
Int. J. Biochem. Cell Biol.43:120-129(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PLK3;SUBCELLULAR LOCATION (ISOFORM 1)
34.

"Calcium-dependent inhibition of polo-like kinase 3 activity by CIB1 in breast cancer cells."
Naik M.U. , Pham N.T. , Beebe K. , Dai W. , Naik U.P.
Int. J. Cancer128:587-596(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PLK3
35.

"Contra-regulation of calcium- and integrin-binding protein 1-induced cell migration on fibronectin by PAK1 and MAP kinase signaling."
Naik M.U. , Naik U.P.
J. Cell. Biochem.112:3289-3299(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION (ISOFORM 1)
36.

"Calcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cells."
Kostyak J.C. , Naik U.P.
PLoS ONE6:E14513-E14513(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PLK3
37.

"Biophysical and structural studies of the human calcium- and integrin-binding protein family: understanding their functional similarities and differences."
Huang H. , Bogstie J.N. , Vogel H.J.
Biochem. Cell Biol.90:646-656(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ITGA2B
38.

"Identification of novel integrin binding partners for calcium and integrin binding protein 1 (CIB1): structural and thermodynamic basis of CIB1 promiscuity."
Freeman T.C. Jr. , Black J.L. , Bray H.G. , Dagliyan O. , Wu Y.I. , Tripathy A. , Dokholyan N.V. , Leisner T.M. , Parise L.V.
Biochemistry52:7082-7090(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ITGA5 AND ITGAV;MUTAGENESIS OF 114-ILE--PHE-117; 152-LEU-ILE-153 AND PHE-173
39.

"CIB1 prevents nuclear GAPDH accumulation and non-apoptotic tumor cell death via AKT and ERK signaling."
Leisner T.M. , Moran C. , Holly S.P. , Parise L.V.
Oncogene32:4017-4027(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
40.

"Structures of the platelet calcium- and integrin-binding protein and the alphaIIb-integrin cytoplasmic domain suggest a mechanism for calcium-regulated recognition; homology modelling and NMR studies."
Hwang P.M. , Vogel H.J.
J. Mol. Recognit.13:83-92(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 9-191
41.

"Structural and biochemical characterization of CIB1 delineates a new family of EF-hand-containing proteins."
Gentry H.R. , Singer A.U. , Betts L. , Yang C. , Ferrara J.D. , Sondek J. , Parise L.V.
J. Biol. Chem.280:8407-8415(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.99 ANGSTROMS) OF 9-191 IN COMPLEX WITH CALCIUM IONS;SUBUNIT
42.

"The crystal structure of calcium- and integrin-binding protein 1: insights into redox regulated functions."
Blamey C.J. , Ceccarelli C. , Naik U.P. , Bahnson B.J.
Protein Sci.14:1214-1221(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 9-191
43.

"Solution structures of Ca2+-CIB1 and Mg2+-CIB1 and their interactions with the platelet integrin alphaIIb cytoplasmic domain."
Huang H. , Ishida H. , Yamniuk A.P. , Vogel H.J.
J. Biol. Chem.286:17181-17192(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-191 IN COMPLEXES WITH CALCIUM IONS AND MAGNESIUM ION;INTERACTION WITH ITGA2B
44.

"Structural basis for the activation of platelet integrin alphaIIbbeta3 by calcium- and integrin-binding protein 1."
Huang H. , Vogel H.J.
J. Am. Chem. Soc.134:3864-3872(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-191 IN COMPLEX WITH ITGA2B PEPTIDE AND CALCIUM IONS;INTERACTION WITH ITGA2B

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