CILP ELISA Kit for Pig(Sus scrofa) | EIAab.comCILP ELISA Kit for Pig(Sus scrofa)

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CILP (Gene name),

Cartilage intermediate layer protein 1 (Protein name ), CILP1_PIG from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CILP(NTPPH);

Protein name:

Cartilage intermediate layer protein 1(CILP-1);

Alternative:

Organism:

Pig (Sus scrofa).

General Annotation

Sub Unit:

Monomer. Interacts with TGFB1.

Function:

Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage.

Subcellular Location:

Secreted extracellular space extracellular matrix

Protein Attributes:

Sequence length:

599

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

599:

STSARPSPAS | TVRGRAPSRR | QRASSGSQRQ | PRGVASLRFP | GVAQQPLSN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9823.ENSSSCP00000005303

UniGene:

Ssc.14477

Uniprot:

O19112

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ELISA Kit for Pig CILP-1

Cat.:

E1182m

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Packing:

96T

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ELISA Kit for Pig CILP-1

Cat.:

E1182h

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Manual:

Looking for manual.

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Packing:

96T

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ELISA Kit for Pig CILP-1

Cat.:

E1182p

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Pig CILP-1

Cat.:

U1182m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Pig CILP-1

Cat.:

U1182p

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Pig CILP-1

Cat.:

U1182h

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Packing:

96T

Polyclonal Antibody for Pig CILP-1

Cat.:

P1182Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Pig CILP-1

Cat.:

P1182Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Pig CILP-1

Protein for Pig CILP-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning and expression of a porcine chondrocyte nucleotide pyrophosphohydrolase."
Masuda I. , Halligan B.D. , Barbieri J.T. , Haas A.L. , Ryan L.M. , McCarty D.J.
Gene197:277-287(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"A unique ectonucleotide pyrophosphohydrolase associated with porcine chondrocyte-derived vesicles."
Masuda I. , Hamada J. , Haas A.L. , Ryan L.M. , McCarty D.J.
J. Clin. Invest.95:699-704(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 141-167
3.

Masuda I. , Hamada J. , Haas A.L. , Ryan L.M. , McCarty D.J.
J. Clin. Invest.96:1179-1179(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
4.

"Expression of cartilage intermediate layer protein/nucleotide pyrophosphohydrolase parallels the production of extracellular inorganic pyrophosphate in response to growth factors and with aging."
Hirose J. , Masuda I. , Ryan L.M.
Arthritis Rheum.43:2703-2711(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
5.

"Variations in site and levels of expression of chondrocyte nucleotide pyrophosphohydrolase with aging."
Masuda I. , Iyama K. , Halligan B.D. , Barbieri J.T. , Haas A.L. , McCarty D.J. , Ryan L.M.
J. Bone Miner. Res.16:868-875(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE

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