Gene name:
Cgn (Kiaa1319) ;
Protein name:
Cingulin ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homodimer. Interacts with TJP1/ZO-1.
Function:
Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
Subcellular Location:
Cell junction
tight junction
Localizes to the apical junction complex composed of tight and adherens junctions.
Protein Attributes:
50:
MADPRGPVDH | GVQIRFITEP | EGATEMGTLR | RSGRRPARDA | RASTYGVAVR |
100:
VQGIAGQPFV | VLNSGEKGTD | SFGVQIKGGN | NRGSPGALSS | DSELPENPYS |
150:
QVKGRPATSR | SSTSDEEPKD | HLNGKLIRSQ | SQASLTGLAF | MSPSNRSTSL |
200:
LELAPKPTSS | INTIDTAPLS | SVDSLINKFD | SQKGGQVRGR | TGRRTRTLPH |
250:
EQRKRSQSLD | SRLPRDTREE | REHQSANHWT | RGTKYDNHVD | SSKNPSQKQS |
300:
PFSSFSRSRQ | TQDWVLQSFE | ETRDPAMVQF | KSTPDLLRDQ | RETAPPGSAD |
350:
HVKATIYGIL | REGSSESEAS | VRRKVSLVLE | QMQPLGMVSP | ASTKALAGQA |
400:
ELTRKMEELQ | KKLDEEVKKR | QKLEPSRVGL | ERQLEEKAEE | CHRLQELLER |
450:
RKGEVQQSSK | ELQNMKLLLG | QEEGLRHGLE | AQVKELQLKL | KHSQSPDSGK |
500:
ESLLKDLLDT | RELLEELLEG | KQRVEEQLRL | RERELTALKG | ALKEEVASHD |
550:
QEVEHVRLQY | QRDTEQLRRS | MQDATQDHAA | LEAERQKMSS | LVRELQRELE |
600:
ETSEETGHWQ | SMFQKNKEEL | RATKQELLQL | RMEKEEMEEE | LGEKMEVLQR |
650:
DLEQARASTR | DTHQVEELKK | ELRRTQGELK | ELQAEQQNQE | VTGRHRNQVL |
700:
EKQLAALREE | ADRGRELEQQ | NLQLQKTLQQ | LRQDCEEASK | AKVASETEAM |
750:
MLGQRRATVE | TTLRETQEEN | DEFRRRILGL | EQQLKEARGL | AEGGEAVEAR |
800:
LRDKVHRLEV | EKQQLEEALN | AAQEEEGNLA | AAKRALEVRL | DEAQRGLARL |
850:
GQEQQALNRA | LEEEGKQREA | LRRSKAELEE | QKRLLNRTVD | RLNKELEQIG |
900:
DDSKLALQQL | QAQMEDYKEK | ARKEVADAQR | QAKDWASEAE | KNSGGLSRLQ |
950:
DELQRLRQAL | QTSQAERDTA | RLDKELLAQR | LQGLEQEAEN | KKRFQDDKAR |
1000:
QLKSLEEKVS | RLEAELDEEK | NTVELLTDRV | NRGRDQVDQL | RTELMQERSA |
1050:
RQDLECDKIS | LERQNKDLKT | RLASSEGFQK | PSASLSQLES | QNQLLQERLQ |
1100:
AEEREKTVLQ | STNRKLERRV | KELSIQIDDE | RQHVNDQKDQ | LTLRVKALKR |
1150:
QVDEAEEEIE | RLDSLRKKAQ | RELEEQHEVN | EQLQARIKSL | EKDAWRKASR |
1191:
SAAESALKQE | GLSSDEEFDN | VYDPSSIASL | LTESNLQTSS | C
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Dog
Mouse
Human
ELISA Kit for Mouse Cingulin
ELISA Kit for Mouse Cingulin
ELISA Kit for Mouse Cingulin
CLIA Kit for Mouse Cingulin
CLIA Kit for Mouse Cingulin
CLIA Kit for Mouse Cingulin
Polyclonal Antibody for Mouse Cingulin
Polyclonal Antibody for Mouse Cingulin
Polyclonal Antibody for Mouse Cingulin
Monoclonal Antibody for Mouse Cingulin
Monoclonal Antibody for Mouse Cingulin
Monoclonal Antibody for Mouse Cingulin
Protein for Mouse Cingulin
Protein for Mouse Cingulin
Protein for Mouse Cingulin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N.
,
Kikuno R.
,
Ohara R.
,
Inamoto S.
,
Koseki H.
,
Hiraoka S.
,
Saga Y.
,
Seino S.
,
Nishimura M.
,
Kaisho T.
,
Hoshino K.
,
Kitamura H.
,
Nagase T.
,
Ohara O.
,
Koga H.
DNA Res.11:205-218(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Pancreatic islet .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain :
FVB/N .
tissue :
Mammary tumor .
tissue :
Trophoblast stem cell .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;TISSUE SPECIFICITY
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-84; SER-92; SER-134 AND SER-326;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .