Protein name:
Cbp/p300-interacting transactivator 4 ;
Alternative:
MSG1-related protein 2 (MRG-2) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts via its C-terminal region with the CH1 domain of CREBBP and EP300. Interacts with all TFAP2/AP-2 isoforms.
Function:
Acts as transcriptional coactivator for TFAP2/AP-2. Enhances estrogen-dependent transactivation mediated by estrogen receptors. May function as an inhibitor of transactivation by HIF1A by disrupting HIF1A interaction with CREBBP. May be involved in regulation of gene expression during development and differentiation of blood cells, endothelial cells and mammary epithelial cells.
Subcellular Location:
Nucleus
Cytoplasm
Protein Attributes:
50:
MADHLMLAEG | YCLLQVPPHT | HGPHAPRTLQ | PYAGPGMDSG | LRPRGAPLGP |
100:
PPPPGTLAYG | SFGSPVSFQP | FPVSQSPGAG | STHLQSAATP | SPGRIPAPPA |
150:
AAGGPSPLQP | APGAAASLPP | PPPPPALGCM | DTELIDEEAL | TSLELELGLH |
182:
RVRELPELFL | GQSEFDCFSD | LGSAPAAGSV | SC
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Bovine
Mouse
ELISA Kit for Mouse Cbp/p300-interacting transactivator 4
ELISA Kit for Mouse Cbp/p300-interacting transactivator 4
ELISA Kit for Mouse Cbp/p300-interacting transactivator 4
ELISA Kit for Mouse Cbp/p300-interacting transactivator 4
CLIA Kit for Mouse Cbp/p300-interacting transactivator 4
CLIA Kit for Mouse Cbp/p300-interacting transactivator 4
CLIA Kit for Mouse Cbp/p300-interacting transactivator 4
CLIA Kit for Mouse Cbp/p300-interacting transactivator 4
Polyclonal Antibody for Mouse Cbp/p300-interacting transactivator 4
Polyclonal Antibody for Mouse Cbp/p300-interacting transactivator 4
Polyclonal Antibody for Mouse Cbp/p300-interacting transactivator 4
Polyclonal Antibody for Mouse Cbp/p300-interacting transactivator 4
Monoclonal Antibody for Mouse Cbp/p300-interacting transactivator 4
Monoclonal Antibody for Mouse Cbp/p300-interacting transactivator 4
Monoclonal Antibody for Mouse Cbp/p300-interacting transactivator 4
Monoclonal Antibody for Mouse Cbp/p300-interacting transactivator 4
Protein for Mouse Cbp/p300-interacting transactivator 4
Protein for Mouse Cbp/p300-interacting transactivator 4
Protein for Mouse Cbp/p300-interacting transactivator 4
Protein for Mouse Cbp/p300-interacting transactivator 4
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Cloning of mouse Cited4, a member of the CITED family p300/CBP-binding transcriptional coactivators: induced expression in mammary epithelial cells."
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Genomics80:601-613(2002)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH CREBBP; EP300 AND TFAP2;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
tissue :
Mammary gland .
2.
"The transcriptional landscape of the mammalian genome."
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
C57BL/6J .
strain :
NOD .
tissue :
Embryo .
tissue :
Thymus .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)
strain :
NMRI .
tissue :
Mammary gland .
4.
"Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein."
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,
Shao W.
,
Endoh H.
,
Hur J.
,
Coser K.R.
,
Sun H.
,
Ueda Y.
,
Kato S.
,
Isselbacher K.J.
,
Brown M.
,
Shioda T.
Genes Dev.15:2598-2612(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION