C-type lectin domain family 2 member I (Protein name
), CLC2I_MOUSE from NCBI database.
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Gene name:
Clec2i(Clrg;Dcl1;Ocilrp2);
Protein name:
C-type lectin domain family 2 member I;
Alternative:
C-type lectin-related protein G(Clr-g);C-type lectin-related protein DCL1;Osteoclast inhibitory lectin-related protein 2(Ocil-related protein 2);Lymphoid-derived C-type lectin-1(LCL-1);
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
N/A
Function:
Inhibits osteoclast formation. Receptor for KLRB1F. Enhances T-cell activation. Plays a role in splenocyte activation, T-cell responses and IL-2 production.
Subcellular Location:
Cell membrane
Single-pass type II membrane protein
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Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
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Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1 AND 2);FUNCTION;INDUCTION;TISSUE SPECIFICITY
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Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3 AND 4);FUNCTION;SUBCELLULAR LOCATION;INDUCTION;TISSUE SPECIFICITY
"A novel c-type lectin (DCL1) expressed in bone marrow derived dendritic cells." Gorski K.S.
,
Huang X.
,
Pardoll D.M.
,
Tsuchiya H.
Submitted (1999-01) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)