Gene name:
CLEC7A (DECTIN1) ;
Protein name:
C-type lectin domain family 7 member A ;
Alternative:
Dendritic cell-associated C-type lectin 1 (DC-associated C-type lectin 1;Dectin-1) ;
Organism:
Bovine (Bos taurus).
General Annotation
Function:
Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation.
Subcellular Location:
Cell membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MEYQSSVENL | DEDGYTQLDF | SSRNITRRSV | VSEKGLCAAS | SHWRLIAVTL |
100:
GILCSVMLVI | TVVLSTSGIW | RSSSGNNLLK | SDSFPSRNKD | NQSQPTQSSL |
150:
EDSVIPTKAL | TTTGVFSSSC | PPNWITHEDS | CYLFSTLLDS | WDGSKRQCFQ |
200:
LGSHLLKIDS | SKELEFISRQ | VSSQPDHSFW | IGLSRRQTEE | PWLWEDGSTL |
247:
LSNLFQIRST | VTEKDSSHNC | AWIHVSDIYD | QLCSVHSYSI | CEKKLSV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Mouse
ELISA Kit for Bovine C-type lectin domain family 7 member A
ELISA Kit for Bovine C-type lectin domain family 7 member A
ELISA Kit for Bovine C-type lectin domain family 7 member A
CLIA Kit for Bovine C-type lectin domain family 7 member A
CLIA Kit for Bovine C-type lectin domain family 7 member A
CLIA Kit for Bovine C-type lectin domain family 7 member A
Polyclonal Antibody for Bovine C-type lectin domain family 7 member A
Polyclonal Antibody for Bovine C-type lectin domain family 7 member A
Polyclonal Antibody for Bovine C-type lectin domain family 7 member A
Monoclonal Antibody for Bovine C-type lectin domain family 7 member A
Monoclonal Antibody for Bovine C-type lectin domain family 7 member A
Monoclonal Antibody for Bovine C-type lectin domain family 7 member A
Protein for Bovine C-type lectin domain family 7 member A
Protein for Bovine C-type lectin domain family 7 member A
Protein for Bovine C-type lectin domain family 7 member A
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);TISSUE SPECIFICITY
tissue :
Bone marrow .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
strain :
Crossbred X Angus .
tissue :
Ileum .