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Index > Protein center > Clca4(Gene name) > Mouse
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  • Clca4 (Gene name),
  • Calcium-activated chloride channel regulator 4 (Protein name ),  CLCA4_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Vaild Sequence
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  • Gene name:
    Clca4(Clca6);
    Protein name:
    Calcium-activated chloride channel regulator 4;
    Alternative:
    Calcium-activated chloride channel regulator 6(mClca6);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May be involved in mediating calcium-activated chloride conductance.
    Subcellular Location:
    Cell membrane Single-pass membrane protein Apical cell membrane Secreted The C-terminus 30 kDa form is anchored to the membrane. The N-terminus 110 kDa form is released from the membrane triggered by an unknown stimulus. Associated with the microvilli of non-goblet cell enterocytes in the small and large intestine. Co-localizes with CFTR.
    Protein Attributes:
    Sequence length:
    924
    Sequence:
    50:
    MAFSRGPVFL | LLLLYLLWGS | DTSLIRLNEN | GYEDIIIAID | PAVPEDTTII | 
    100:
    EHIKGMVTKA | STYLFEATEK | RFFFKNVSIL | IPESWKDSPQ | YRRPKQESYK | 
    150:
    HADIKVAPPT | VEGRDEPYTR | QFTQCEEKAE | YIHFTPDFVL | GRKQDEYGDS | 
    200:
    GKVLVHEWAH | LRWGVFDEYN | EDQPFYSASS | KKIEATRCST | GITGTNRVYA | 
    250:
    CQGGSCAMRR | CRTNSTTKLY | EKDCQFFPDK | VQSEKASIMF | MQSIDSVTEF | 
    300:
    CKKENHNREA | PTLHNKKCNY | RSTWEVISTS | EDFNSSTPME | TSPSPPFFSL | 
    350:
    LRISERIMCL | VLDVSGSMTS | YDRLNRMNQA | AKYFLSQIIE | NRSWVGMVHF | 
    400:
    SSQATIVHEL | IQINSDIERN | QLLQTLPTSA | NGGTSICSGI | KAAFQVFKNG | 
    450:
    EYQTDGTEIL | LLSDGEDSTA | KDCIDEVKDS | GSIVHFIALG | PLADLAVTNM | 
    500:
    SILTGGNHKL | ATDEAQNNGL | IDAFGALASE | NADITQKSLQ | LESKGAILNN | 
    550:
    SLWLNDTVVI | DSTLGRDTFF | LVTWSKQAPA | IYLRDPKGTQ | TTNFTMDSAS | 
    600:
    KMAYLSIPGT | AQVGVWTYNL | EAKENSEILT | ITVTSRAANS | SVPPITVNAK | 
    650:
    VNTDTNTFPS | PMIVYAEVLQ | GYTPIIGARV | TATIESNSGK | TEELVLLDNG | 
    700:
    AGADAFKDDG | VYSRFFTAYS | VNGRYSLKVR | ADGGRNSARR | SLRHPSSRAA | 
    750:
    YIPGWVVDGE | IQGNPPRPET | TEATQPVLEN | FSRTASGGAF | VVSNVPSGPL | 
    800:
    PDLYPPNQIT | DLQATLDGEE | ISLTWTAPGD | DYDVGRVQQY | IIRTSKNIIE | 
    850:
    LRDNFNNSPR | VDTTNLTPKE | ANSEETFAFK | PENITEENAT | YIFIAIESVD | 
    900:
    KSSLSSGPSN | IAQVALFTPQ | AEPDPDESPS | SSGVSVATIV | LSVLGALVLV | 
    924:
    CIIVGTTICI | LKNKRSSSAA | ITKF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Calcium-activated chloride channel regulator 4
    ELISA Kit for Mouse Calcium-activated chloride channel regulator 4
    CLIA Kit for Mouse Calcium-activated chloride channel regulator 4
    CLIA Kit for Mouse Calcium-activated chloride channel regulator 4
    Polyclonal Antibody for Mouse Calcium-activated chloride channel regulator 4
    Polyclonal Antibody for Mouse Calcium-activated chloride channel regulator 4
    Monoclonal Antibody for Mouse Calcium-activated chloride channel regulator 4
    Monoclonal Antibody for Mouse Calcium-activated chloride channel regulator 4
    Protein for Mouse Calcium-activated chloride channel regulator 4
    Protein for Mouse Calcium-activated chloride channel regulator 4

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Molecular and functional analyses of two new calcium-activated chloride channel family members from mouse eye and intestine."
      Evans S.R. , Thoreson W.B. , Beck C.L.
      J. Biol. Chem.279:41792-41800(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;GLYCOSYLATION;PROCESSING
      strain: C57BL/6 x SJL/J.
      tissue: Intestine.
    2. 2.
      "Murine mCLCA6 is an integral apical membrane protein of non-goblet cell enterocytes and co-localizes with the cystic fibrosis transmembrane conductance regulator."
      Bothe M.K. , Braun J. , Mundhenk L. , Gruber A.D.
      J. Histochem. Cytochem.56:495-509(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;GLYCOSYLATION;SYNTHESIS OF 85-98; 106-119; 803-817 AND 870-882;PROCESSING
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