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Index > Protein center > Clcnka(Gene name) > Rat
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  • Clcnka (Gene name),
  • Chloride channel protein ClC-Ka (Protein name ),  CLCKA_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Clcnka(Clcnk1);
    Protein name:
    Chloride channel protein ClC-Ka(Chloride channel Ka);
    Alternative:
    ClC-K1;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with BSND.
    Function:
    Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    687
    Sequence:
    50:
    MEELVGLREG | SSGKPVTLQE | LWGPCPRIRR | GVRRGLEWLK | ERLFRVGEDW | 
    100:
    HFLVALGVLM | ALISYAMNFA | IGRVVRAHKW | LYREVGDGHL | LRYLSWTVYP | 
    150:
    VALLSFSSGF | SQSISPFSGG | SGLPELKTML | SGVVLEDYLD | IKNFGAKVVG | 
    200:
    LSCTLATGST | IFLGKVGPFV | HLSVMISAYL | GRVRAKTIGE | TENKAKEIEM | 
    250:
    LSAAAAVGVA | TVFAAPFSGV | LFSIEVMSSH | FSVWNYWRGF | FAATCGAFMF | 
    300:
    RLLGVFNSEQ | ETITSIYKTR | FRVDVPFDLP | EIFFFVALGF | ICGVLSCAYL | 
    350:
    FCQRTFLRFI | KTNRYTSRLL | ATSKPSYAAL | VALVLASITY | PPGVGRFMAS | 
    400:
    RLSMAEHLHS | LFDNNSWALM | TRNSSPPWPA | EPDPQNLWLE | WCHPRFTIFG | 
    450:
    TLAFFLVMKF | WMLILATTIP | MPAGYFMPIF | IIGAAIGRLL | GEALSVAFPE | 
    500:
    GIVAGREVNP | IMPGGYALAG | AAAFSGAVTH | TISTALLAFE | LTGQIVHALP | 
    550:
    VLMAVLAANA | ISQNCQPSFY | DGTIMAKKLP | YLPWIRGRQI | GSYPVTVEHF | 
    600:
    MNCNLTTLAK | DTPLEEVVKV | VTSTEVSQYP | LVETRESQTL | VGIVERTHLV | 
    650:
    QALQTQPASW | APGQERFLQD | ILAGGCPTQP | VTLQLSPETS | LYQAHSLFER | 
    687:
    LTLQSLFVTS | RGKAVGSVSW | AELKKAISTL | INPPAPK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    UniGene:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Chloride channel Ka
    ELISA Kit for Rat Chloride channel Ka
    ELISA Kit for Rat Chloride channel Ka
    ELISA Kit for Rat Chloride channel Ka
    CLIA Kit for Rat Chloride channel Ka
    CLIA Kit for Rat Chloride channel Ka
    CLIA Kit for Rat Chloride channel Ka
    CLIA Kit for Rat Chloride channel Ka
    Polyclonal Antibody for Rat Chloride channel Ka
    Polyclonal Antibody for Rat Chloride channel Ka
    Polyclonal Antibody for Rat Chloride channel Ka
    Polyclonal Antibody for Rat Chloride channel Ka
    Monoclonal Antibody for Rat Chloride channel Ka
    Monoclonal Antibody for Rat Chloride channel Ka
    Monoclonal Antibody for Rat Chloride channel Ka
    Monoclonal Antibody for Rat Chloride channel Ka
    Protein for Rat Chloride channel Ka
    Protein for Rat Chloride channel Ka
    Protein for Rat Chloride channel Ka
    Protein for Rat Chloride channel Ka

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning of a chloride channel that is regulated by dehydration and expressed predominantly in kidney medulla."
      Uchida S. , Sasaki S. , Furukawa T. , Hiraoka M. , Imai T. , Hirata Y. , Marumo F.
      J. Biol. Chem.268:3821-3824(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Kidney.
    2. 2.
      "Molecular cloning of a chloride channel that is regulated by dehydration and expressed predominantly in kidney medulla."
      Uchida S. , Sasaki S. , Furukawa T. , Hiraoka M. , Imai T. , Hirata Y. , Marumo F.
      J. Biol. Chem.269:19192-19192(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
      strain: Sprague-Dawley.
      tissue: Kidney.
    3. 3.
      Uchida S.
      Submitted (1996-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
      strain: Sprague-Dawley.
      tissue: Kidney.
    4. 4.
      "Two highly homologous members of the ClC chloride channel family in both rat and human kidney."
      Kieferle S. , Fong P. , Bens M. , Vandewalle A. , Jentsch T.
      Proc. Natl. Acad. Sci. U.S.A.91:6943-6947(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Kidney.
    5. 5.
      "Barttin increases surface expression and changes current properties of ClC-K channels."
      Waldegger S. , Jeck N. , Barth P. , Peters M. , Vitzthum H. , Wolf K. , Kurtz A. , Konrad M. , Seyberth H.W.
      Pflugers Arch.444:411-418(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BSND
    6. 6.
      "Parallel down-regulation of chloride channel CLC-K1 and barttin mRNA in the thin ascending limb of the rat nephron by furosemide."
      Wolf K. , Meier-Meitinger M. , Bergler T. , Castrop H. , Vitzthum H. , Riegger G.A.J. , Kurtz A. , Kraemer B.K.
      Pflugers Arch.446:665-671(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DOWN-REGULATION BY FUROSEMIDE
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