Gene name:
Clcnkb (Clckb;Clcnk1l) ;
Protein name:
Chloride channel protein ClC-Kb (Chloride channel Kb) ;
Alternative:
ClC-K2 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with BSND. Forms heteromers with BSND in the thick ascending limb of Henle and more distal segments.
Function:
Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms. May be the basolateral chloride channel mediating net chloride absorption in CTAL cells.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MEELVGLREG | ASKKPVPLQE | LWGPCPRIRR | NIQGGLEWLK | ERLFRVGEDW |
100:
YFLVALGVLM | ALISYAMNFT | IGRVVRAHKW | LYREIGDGHL | LRYLSWTVYP |
150:
VALLSFSSGF | SQSITPSSGG | SGIPEVKTIL | TGVVLEDYLD | IKNFGAKVVG |
200:
LSCTLATGST | IFLGKLGPFV | HLSVMIAAYL | GRVRTKTVGE | PESKTKEMEL |
250:
LAAGAAVGVA | TVFAAPISGV | LFSIEVMSSH | FSVWDYWRGF | FAATCGAFMF |
300:
HLLAVFNNEQ | ETITSIYKTS | FPVDIPFDLP | EIFFFVALGA | ICGILSCGYN |
350:
YSQRTFLFFL | KANGFTSKLL | ATSKPLYSAL | AAVVLASITY | PPGVGHFMAS |
400:
RLSMSEHLET | LFDNNSWALM | TKNSSPPWAA | EPDPQKLWLE | WCHPQLTVFG |
450:
TLVFFLVMKF | WMLILATTIP | IPAGYFLPIF | IYGAVIGRLF | GEVLSVAFPE |
500:
GIVAGGRVNP | IMPGAYALAG | AAAFSGAVTH | TLSTALLAFE | VTGQLVHALP |
550:
VLMAVLAANA | ISQSFQPSFY | DGTIIVKKLP | YLPWIRGRQI | GSHSVTVGHF |
600:
MNCALTTLAK | DMPLEQVIQV | VISTDVTQYP | LVETTESQTL | VGVVKRTHLV |
650:
QALQTEPASW | APGQQPCLQD | ILANGCPTQP | VTLQLSLETS | LHETHNLFEL |
687:
LNLQTLFVTS | RGRAVGSVSW | VELKKAISTL | TNPPAPK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rabbit
Rat
Mouse
Human
ELISA Kit for Mouse Chloride channel Kb
ELISA Kit for Mouse Chloride channel Kb
ELISA Kit for Mouse Chloride channel Kb
ELISA Kit for Mouse Chloride channel Kb
CLIA Kit for Mouse Chloride channel Kb
CLIA Kit for Mouse Chloride channel Kb
CLIA Kit for Mouse Chloride channel Kb
CLIA Kit for Mouse Chloride channel Kb
Polyclonal Antibody for Mouse Chloride channel Kb
Polyclonal Antibody for Mouse Chloride channel Kb
Polyclonal Antibody for Mouse Chloride channel Kb
Polyclonal Antibody for Mouse Chloride channel Kb
Monoclonal Antibody for Mouse Chloride channel Kb
Monoclonal Antibody for Mouse Chloride channel Kb
Monoclonal Antibody for Mouse Chloride channel Kb
Monoclonal Antibody for Mouse Chloride channel Kb
Protein for Mouse Chloride channel Kb
Protein for Mouse Chloride channel Kb
Protein for Mouse Chloride channel Kb
Protein for Mouse Chloride channel Kb
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);POSSIBLE FUNCTION;TISSUE SPECIFICITY
tissue :
Kidney outer medulla .
2.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
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Goodstadt L.
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Hillier L.W.
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Zody M.C.
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Goldstein S.
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She X.
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Bult C.J.
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Agarwala R.
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Cherry J.L.
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DiCuccio M.
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Hlavina W.
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Kapustin Y.
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Meric P.
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Maglott D.
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Birtle Z.
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Marques A.C.
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Graves T.
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Zhou S.
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Teague B.
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Potamousis K.
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Churas C.
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Place M.
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Herschleb J.
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Runnheim R.
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Forrest D.
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Amos-Landgraf J.
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Cheng Z.
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Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
strain :
FVB/N .
tissue :
Salivary gland .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH BSND;SUBCELLULAR LOCATION;TISSUE SPECIFICITY