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Index > Protein center > Clcnkb(Gene name) > Mouse
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  • Clcnkb (Gene name),
  • Chloride channel protein ClC-Kb (Protein name ),  CLCKB_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Clcnkb(Clckb;Clcnk1l);
    Protein name:
    Chloride channel protein ClC-Kb(Chloride channel Kb);
    Alternative:
    ClC-K2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with BSND. Forms heteromers with BSND in the thick ascending limb of Henle and more distal segments.
    Function:
    Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms. May be the basolateral chloride channel mediating net chloride absorption in CTAL cells.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    687
    Sequence:
    50:
    MEELVGLREG | ASKKPVPLQE | LWGPCPRIRR | NIQGGLEWLK | ERLFRVGEDW | 
    100:
    YFLVALGVLM | ALISYAMNFT | IGRVVRAHKW | LYREIGDGHL | LRYLSWTVYP | 
    150:
    VALLSFSSGF | SQSITPSSGG | SGIPEVKTIL | TGVVLEDYLD | IKNFGAKVVG | 
    200:
    LSCTLATGST | IFLGKLGPFV | HLSVMIAAYL | GRVRTKTVGE | PESKTKEMEL | 
    250:
    LAAGAAVGVA | TVFAAPISGV | LFSIEVMSSH | FSVWDYWRGF | FAATCGAFMF | 
    300:
    HLLAVFNNEQ | ETITSIYKTS | FPVDIPFDLP | EIFFFVALGA | ICGILSCGYN | 
    350:
    YSQRTFLFFL | KANGFTSKLL | ATSKPLYSAL | AAVVLASITY | PPGVGHFMAS | 
    400:
    RLSMSEHLET | LFDNNSWALM | TKNSSPPWAA | EPDPQKLWLE | WCHPQLTVFG | 
    450:
    TLVFFLVMKF | WMLILATTIP | IPAGYFLPIF | IYGAVIGRLF | GEVLSVAFPE | 
    500:
    GIVAGGRVNP | IMPGAYALAG | AAAFSGAVTH | TLSTALLAFE | VTGQLVHALP | 
    550:
    VLMAVLAANA | ISQSFQPSFY | DGTIIVKKLP | YLPWIRGRQI | GSHSVTVGHF | 
    600:
    MNCALTTLAK | DMPLEQVIQV | VISTDVTQYP | LVETTESQTL | VGVVKRTHLV | 
    650:
    QALQTEPASW | APGQQPCLQD | ILANGCPTQP | VTLQLSLETS | LHETHNLFEL | 
    687:
    LNLQTLFVTS | RGRAVGSVSW | VELKKAISTL | TNPPAPK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    SMR:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Chloride channel Kb
    ELISA Kit for Mouse Chloride channel Kb
    ELISA Kit for Mouse Chloride channel Kb
    ELISA Kit for Mouse Chloride channel Kb
    CLIA Kit for Mouse Chloride channel Kb
    CLIA Kit for Mouse Chloride channel Kb
    CLIA Kit for Mouse Chloride channel Kb
    CLIA Kit for Mouse Chloride channel Kb
    Polyclonal Antibody for Mouse Chloride channel Kb
    Polyclonal Antibody for Mouse Chloride channel Kb
    Polyclonal Antibody for Mouse Chloride channel Kb
    Polyclonal Antibody for Mouse Chloride channel Kb
    Monoclonal Antibody for Mouse Chloride channel Kb
    Monoclonal Antibody for Mouse Chloride channel Kb
    Monoclonal Antibody for Mouse Chloride channel Kb
    Monoclonal Antibody for Mouse Chloride channel Kb
    Protein for Mouse Chloride channel Kb
    Protein for Mouse Chloride channel Kb
    Protein for Mouse Chloride channel Kb
    Protein for Mouse Chloride channel Kb

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cl(-) channels in basolateral TAL membranes XV. Molecular heterogeneity between cortical and medullary channels."
      Winters C.J. , Zimniak L. , Mikhailova M.V. , Reeves W.B. , Andreoli T.E.
      J. Membr. Biol.177:221-230(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);POSSIBLE FUNCTION;TISSUE SPECIFICITY
      tissue: Kidney outer medulla.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: FVB/N.
      tissue: Salivary gland.
    5. 5.
      "Barttin is a Cl- channel beta-subunit crucial for renal Cl-reabsorption and inner ear K+ secretion."
      Estevez R. , Boettger T. , Stein V. , Birkenhaeger R. , Otto E. , Hildebrandt F. , Jentsch T.J.
      Nature414:558-561(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BSND;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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