Clcnkb ELISA Kit for Rat(Rattus norvegicus) | EIAab.comClcnkb ELISA Kit for Rat(Rattus norvegicus)

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Clcnkb (Gene name),

Chloride channel protein ClC-Kb (Protein name ), CLCKB_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Clcnkb;

Protein name:

Chloride channel protein ClC-Kb(Chloride channel Kb);

Alternative:

ClC-K2;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with BSND.

Function:

Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms.

Subcellular Location:

Cell membrane Multi-pass membrane protein Golgi apparatus membrane Multi-pass membrane protein Recruited to the plasma membrane in the presence of BSND protein, whereas remains in the Golgi in its absence.

Protein Attributes:

Sequence length:

687

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

687:

LNLQLLFVTS | RGRAVGSVSW | VELKKAISTL | TNPPAPK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:79430

STRING:

10116.ENSRNOP00000013550

UniGene:

Rn.10339

String:

P51802

Pfam:

PF00571

SMR:

P51802

Uniprot:

P51802

FOR

ELISA Kit for Rat Chloride channel Kb

CLIA Kit for Rat Chloride channel Kb

Polyclonal Antibody for Rat Chloride channel Kb

Monoclonal Antibody for Rat Chloride channel Kb

Protein for Rat Chloride channel Kb

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Two highly homologous members of the ClC chloride channel family in both rat and human kidney."
Kieferle S. , Fong P. , Bens M. , Vandewalle A. , Jentsch T.
Proc. Natl. Acad. Sci. U.S.A.91:6943-6947(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Kidney.
2.

"Two isoforms of a chloride channel predominantly expressed in thick ascending limb of Henle's loop and collecting ducts of rat kidney."
Adachi S. , Uchida S. , Hata M. , Hirose M. , Marumo F. , Sasaki S. , Ito H.
J. Biol. Chem.269:17677-17683(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
tissue: Kidney.
3.

"Barttin increases surface expression and changes current properties of ClC-K channels."
Waldegger S. , Jeck N. , Barth P. , Peters M. , Vitzthum H. , Wolf K. , Kurtz A. , Konrad M. , Seyberth H.W.
Pflugers Arch.444:411-418(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BSND
4.

"Molecular mechanisms of Bartter syndrome caused by mutations in the BSND gene."
Hayama A. , Rai T. , Sasaki S. , Uchida S.
Histochem. Cell Biol.119:485-493(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;SUBCELLULAR LOCATION;INDUCTION

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