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Index > Protein center > Cldn15(Gene name) > Mouse
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  • Cldn15 (Gene name),
  • Claudin-15 (Protein name ),  CLD15_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Cldn15;
    Protein name:
    Claudin-15;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
    Subcellular Location:
    Cell junction tight junction Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    227
    Sequence:
    50:
    MSVAVETFGF | FMSALGLLML | GLTLSNSYWR | VSTVHGNVIT | TNTIFENLWY | 
    100:
    SCATDSLGVS | NCWDFPSMLA | LSGYVQGCRA | LMITAILLGF | LGLFLGMVGL | 
    150:
    RCTNVGNMDL | SKKAKLLAIA | GTLHILAGAC | GMVAISWYAV | NITTDFFNPL | 
    200:
    YAGTKYELGP | ALYLGWSASL | LSILGGICVF | STCCCSSKEE | PATRAGLPYK | 
    227:
    PSTVVIPRAT | SDESDISFGK | YGKNAYV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Claudin-15
    Cat.:
    E6038h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Claudin-15
    Cat.:
    E6038b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Claudin-15
    Cat.:
    E6038m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Claudin-15
    Cat.:
    U6038b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Claudin-15
    Cat.:
    U6038h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Claudin-15
    Cat.:
    U6038m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Claudin-15
    Cat.:
    P6038Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Claudin-15
    Polyclonal Antibody for Mouse Claudin-15
    Cat.:
    P6038Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Claudin-15
    Monoclonal Antibody for Mouse Claudin-15
    Monoclonal Antibody for Mouse Claudin-15
    Protein for Mouse Claudin-15
    Protein for Mouse Claudin-15
    Protein for Mouse Claudin-15

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Small intestine.
      tissue: Stomach.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Mammary gland.
    3. 3.
      Morita K. , Furuse M. , Tsukita S.
      Submitted (1999-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-122
      tissue: Lung.
    4. 4.
      "Heterogeneity in expression and subcellular localization of tight junction proteins, claudin-10 and -15, examined by RT-PCR and immunofluorescence microscopy."
      Inai T. , Sengoku A. , Guan X. , Hirose E. , Iida H. , Shibata Y.
      Arch. Histol. Cytol.68:349-360(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION;FUNCTION;TISSUE SPECIFICITY
    6. 6.
      "Loss of claudin-15, but not claudin-2, causes Na+ deficiency and glucose malabsorption in mouse small intestine."
      Tamura A. , Hayashi H. , Imasato M. , Yamazaki Y. , Hagiwara A. , Wada M. , Noda T. , Watanabe M. , Suzuki Y. , Tsukita S.
      Gastroenterology140:913-923(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    7. 7.
      "Loss of claudins 2 and 15 from mice causes defects in paracellular Na+ flow and nutrient transport in gut and leads to death from malnutrition."
      Wada M. , Tamura A. , Takahashi N. , Tsukita S.
      Gastroenterology144:369-380(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION;TISSUE SPECIFICITY
    8. 8.
      "Crystal structure of a claudin provides insight into the architecture of tight junctions."
      Suzuki H. , Nishizawa T. , Tani K. , Yamazaki Y. , Tamura A. , Ishitani R. , Dohmae N. , Tsukita S. , Nureki O. , Fujiyoshi Y.
      Science344:304-307(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 1-194 OF MUTANT ALA-102/ALA-183/ALA-184/ALA-185;SUBCELLULAR LOCATION;SUBUNIT;MUTAGENESIS OF MET-68; CYS-102; 146-PHE-PHE-147 AND 183-CYS--CYS-185;TOPOLOGY;DISULFIDE BOND;PALMITOYLATION
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