Protein name:
Claudin-16 ;
Alternative:
Paracellin-1 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in paracellular magnesium reabsorption. Required for a selective paracellular conductance. May form, alone or in partnership with other constituents, an intercellular pore permitting paracellular passage of magnesium and calcium ions down their electrochemical gradients. Alternatively, it could be a sensor of magnesium concentration that could alter paracellular permeability mediated by other factors.
Subcellular Location:
Cell junction
tight junction
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MKDLLQYAAC | FLAIFSTGFL | IVATRTDCWM | VNADDSLEVS | TKCRGLWWEC |
100:
VTNAFDGIRT | CDEYDSIYAE | HPLKLVVTRA | LMITADILAG | FGFITLLLGL |
150:
DCVKFLPDEP | HIKVRLCFVA | GTVLLIAGTP | GIIGSVWYAV | DVYVERSSLV |
200:
LHNIFLGIQY | KFGWSCWLGM | AGSLGCFLAG | ALLTCCLYLF | KDVGPERNYP |
235:
YAMRKPYSTA | GVSMAKSYKA | PRTETAKMYA | VDTRV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
Bovine
ELISA Kit for Rat Claudin-16
ELISA Kit for Rat Claudin-16
ELISA Kit for Rat Claudin-16
ELISA Kit for Rat Claudin-16
CLIA Kit for Rat Claudin-16
CLIA Kit for Rat Claudin-16
CLIA Kit for Rat Claudin-16
CLIA Kit for Rat Claudin-16
Polyclonal Antibody for Rat Claudin-16
Polyclonal Antibody for Rat Claudin-16
Polyclonal Antibody for Rat Claudin-16
Polyclonal Antibody for Rat Claudin-16
Monoclonal Antibody for Rat Claudin-16
Monoclonal Antibody for Rat Claudin-16
Monoclonal Antibody for Rat Claudin-16
Monoclonal Antibody for Rat Claudin-16
Protein for Rat Claudin-16
Protein for Rat Claudin-16
Protein for Rat Claudin-16
Protein for Rat Claudin-16
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Primary gene structure and expression studies of rodent paracellin-1."
Weber S.
,
Schlingmann K.P.
,
Peters M.
,
Nejsum L.N.
,
Nielsen S.
,
Engel H.
,
Grzeschik K.H.
,
Seyberth H.W.
,
Grone H.J.
,
Nusing R.
,
Konrad M.
J. Am. Soc. Nephrol.12:2664-2672(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Sprague-Dawley .
tissue :
Kidney .