CLDN1 ELISA Kit for Human(Homo sapiens) | EIAab.comCLDN1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CLDN1(Gene name) > Human

CLDN1 (Gene name),

Claudin-1 (Protein name ), CLD1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CLDN1(UNQ481/PRO944;CLD1;SEMP1);

Protein name:

Claudin-1;

Alternative:

Senescence-associated epithelial membrane protein;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN2, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ and INADL (By similarity). May interact with HCV E1 and E2 proteins.

Function:

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity (By similarity). Acts as a co-receptor for HCV entry into hepatic cells.

Subcellular Location:

Cell junction tight junction Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

211

Sequence:

50:

100:

150:

200:

211:

KPAPSSGKDY | V

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

O95832

STRING:

9606.ENSP00000295522

MIM:

603718

Pfam:

PF00822

UniGene:

Hs.439060

KEGG:

hsa:9076

Uniprot:

O95832

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ELISA Kit for Human Claudin-1

Cat.:

E9653h

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96T

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ELISA Kit for Human Claudin-1

Cat.:

E9653r

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96T

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ELISA Kit for Human Claudin-1

Cat.:

E9653m

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96T

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ELISA Kit for Human Claudin-1

Cat.:

E9653b

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96T

CLIA Kit for Human Claudin-1

Cat.:

U9653b

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96T

CLIA Kit for Human Claudin-1

Cat.:

U9653h

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96T

CLIA Kit for Human Claudin-1

Cat.:

U9653m

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Packing:

96T

CLIA Kit for Human Claudin-1

Cat.:

U9653r

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96T

Polyclonal Antibody for Human Claudin-1

Cat.:

P9653Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Claudin-1

Cat.:

P9653Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Claudin-1

Cat.:

P9653Rb-r

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40ug/0.2ml

Monoclonal Antibody for Human Claudin-1

Protein for Human Claudin-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"SEMP1, a senescence-associated cDNA isolated from human mammary epithelial cells, is a member of an epithelial membrane protein superfamily."
Swisshelm K.L. , Machl A. , Planitzer S. , Robertson R. , Kubbies M. , Hosier S.
Gene226:285-295(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
2.

"Human claudin-1 isolated from Caco-2 mRNA."
Mitic L.M. , Anderson J.M.
Submitted (1998-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Assignment of claudin-1 (CLDN1) to human chromosome 3q28-->q29 with somatic cell hybrids."
Halford S. , Spencer P. , Greenwood J. , Winton H. , Hunt D.M. , Adamson P.
Cytogenet. Cell Genet.88:217-217(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"Genomic organization of claudin-1 and its assessment in hereditary and sporadic breast cancer."
Kraemer F. , White K. , Kubbies M. , Swisshelm K.L. , Weber B.H.F.
Hum. Genet.107:249-256(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
6.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Urinary bladder.
8.

"Claudin-1 gene mutations in neonatal sclerosing cholangitis associated with ichthyosis: a tight junction disease."
Hadj-Rabia S. , Baala L. , Vabres P. , Hamel-Teillac D. , Jacquemin E. , Fabre M. , Lyonnet S. , De Prost Y. , Munnich A. , Hadchouel M. , Smahi A.
Gastroenterology127:1386-1390(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN NISCH
9.

"Confirmation of the origin of NISCH syndrome."
Feldmeyer L. , Huber M. , Fellmann F. , Beckmann J.S. , Frenk E. , Hohl D.
Hum. Mutat.27:408-410(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN NISCH
10.

"Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry."
Evans M.J. , von Hahn T. , Tscherne D.M. , Syder A.J. , Panis M. , Wolk B. , Hatziioannou T. , McKeating J.A. , Bieniasz P.D. , Rice C.M.
Nature446:801-805(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HCV E1 AND E2 PROTEINS;MUTAGENESIS OF ILE-32 AND GLU-48
11.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
12.

"Contribution of tight junction proteins to ion, macromolecule, and water barrier in keratinocytes."
Kirschner N. , Rosenthal R. , Furuse M. , Moll I. , Fromm M. , Brandner J.M.
J. Invest. Dermatol.133:1161-1169(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
13.

"Production, purification and characterization of recombinant, full-length human claudin-1."
Bonander N. , Jamshad M. , Oberthuer D. , Clare M. , Barwell J. , Hu K. , Farquhar M.J. , Stamataki Z. , Harris H.J. , Dierks K. , Dafforn T.R. , Betzel C. , McKeating J.A. , Bill R.M.
PLoS ONE8:E64517-E64517(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;SUBUNIT

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