Gene name:
CMIP (KIAA1694;TCMIP) ;
Protein name:
C-Maf-inducing protein (c-Mip) ;
Alternative:
Truncated c-Maf-inducing protein (Tc-Mip) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with FLNA.
Function:
Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor.
Subcellular Location:
Nucleus
Cytoplasm
Isoform 2 is translocated to the nucleus and is specifically recruited during minimal change nephrotic syndrome (MCNS). Detected in nuclear and cytoplasmic compartments during MCNS relapse. Expressed in cytoplasm only during MCNS remission and absent in normal patients.
Protein Attributes:
50:
MDVTSSSGGG | GDPRQIEETK | PLLGGDVSAP | EGTKMGAVPC | RRALLLCNGM |
100:
RYKLLQEGDI | QVCVIRHPRT | FLSKILTSKF | LRRWEPHHLT | LADNSLASAT |
150:
PTGYMENSVS | YSAIEDVQLL | SWENAPKYCL | QLTIPGGTVL | LQAANSYLRD |
200:
QWFHSLQWKK | KIYKYKKVLS | NPSRWEVVLK | EIRTLVDMAL | TSPLQDDSIN |
250:
QAPLEIVSKL | LSENTNLTTQ | EHENIIVAIA | PLLENNHPPP | DLCEFFCKHC |
300:
RERPRSMVVI | EVFTPVVQRI | LKHNMDFGKC | PRLRLFTQEY | ILALNELNAG |
350:
MEVVKKFIQS | MHGPTGHCPH | PRVLPNLVAV | CLAAIYSCYE | EFINSRDNSP |
400:
SLKEIRNGCQ | QPCDRKPTLP | LRLLHPSPDL | VSQEATLSEA | RLKSVVVASS |
450:
EIHVEVERTS | TAKPALTASA | GNDSEPNLID | CLMVSPACST | MSIELGPQAD |
500:
RTLGCYVEIL | KLLSDYDDWR | PSLASLLQPI | PFPKEALAHE | KFTKELKYVI |
550:
QRFAEDPRQE | VHSCLLSVRA | GKDGWFQLYS | PGGVACDDDG | ELFASMVHIL |
600:
MGSCYKTKKF | LLSLAENKLG | PCMLLALRGN | QTMVEILCLM | LEYNIIDNND |
650:
TQLQIISTLE | STDVGKRMYE | QLCDRQRELK | ELQRKGGPTR | LTLPSKSTDA |
700:
DLARLLSSGS | FGNLENLSLA | FTNVTSACAE | HLIKLPSLKQ | LNLWSTQFGD |
750:
AGLRLLSEHL | TMLQVLNLCE | TPVTDAGLLA | LSSMKSLCSL | NMNSTKLSAD |
773:
TYEDLKAKLP | NLKEVDVRYT | EAW
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human c-Mip
ELISA Kit for Human c-Mip
Polyclonal Antibody for Human c-Mip
Polyclonal Antibody for Human c-Mip
Monoclonal Antibody for Human c-Mip
Monoclonal Antibody for Human c-Mip
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
"Truncation of C-mip (Tc-mip), a new proximal signaling protein, induces c-maf Th2 transcription factor and cytoskeleton reorganization."
Grimbert P.
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Valanciute A.
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Le gouvelo S.
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J. Exp. Med.198:797-807(2003)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;SUBCELLULAR LOCATION;ALTERNATIVE SPLICING;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
2.
"The sequence and analysis of duplication-rich human chromosome 16."
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more...
Nature432:988-994(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
tissue :
Brain .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 17-773 (ISOFORM 1)
tissue :
Brain .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH FLNA;SUBCELLULAR LOCATION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-377;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-349;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]