Cmklr1 ELISA Kit for Mouse(Mus musculus) | EIAab.comCmklr1 ELISA Kit for Mouse(Mus musculus)

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Cmklr1 (Gene name),

Chemokine-like receptor 1 (Protein name ), CML1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cmklr1(Dez;Gpcr27);

Protein name:

Chemokine-like receptor 1;

Alternative:

G-protein coupled receptor DEZ;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

371

Sequence:

50:

100:

150:

200:

250:

300:

350:

371:

FTKMSSLNEK | ASVNEKETST | L

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.5196

SMR:

P97468

String:

P97468

KEGG:

mmu:14747

Pfam:

PF00001

Uniprot:

P97468

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ELISA Kit for Mouse Chemokine-like receptor 1

Cat.:

E14031h

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96T

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ELISA Kit for Mouse Chemokine-like receptor 1

Cat.:

E14031m

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96T

ELISA Kit for Mouse Chemokine-like receptor 1

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E14031r

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96T

CLIA Kit for Mouse Chemokine-like receptor 1

Cat.:

U14031m

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96T

CLIA Kit for Mouse Chemokine-like receptor 1

Cat.:

U14031h

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MSDS:

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96T

CLIA Kit for Mouse Chemokine-like receptor 1

Cat.:

U14031r

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96T

Polyclonal Antibody for Mouse Chemokine-like receptor 1

Cat.:

P14031Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse Chemokine-like receptor 1

Cat.:

P14031Rb-r

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40ug/0.2ml

Polyclonal Antibody for Mouse Chemokine-like receptor 1

Cat.:

P14031Rb-m

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40ug/0.2ml

Monoclonal Antibody for Mouse Chemokine-like receptor 1

Protein for Mouse Chemokine-like receptor 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"A novel G protein-coupled receptor with homology to neuropeptide and chemoattractant receptors expressed during bone development."
Methner A. , Hermey G. , Schinke B. , Hermans-Borgmeyer I.
Biochem. Biophys. Res. Commun.233:336-342(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];DEVELOPMENTAL STAGE
tissue: Brain.
2.

"Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1."
Arita M. , Bianchini F. , Aliberti J. , Sher A. , Chiang N. , Hong S. , Yang R. , Petasis N.A. , Serhan C.N.
J. Exp. Med.201:713-722(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: LIGAND-BINDING;FUNCTION
3.

"Chemokine-like receptor 1 expression by macrophages in vivo: regulation by TGF-beta and TLR ligands."
Zabel B.A. , Ohyama T. , Zuniga L. , Kim J.Y. , Johnston B. , Allen S.J. , Guido D.G. , Handel T.M. , Butcher E.C.
Exp. Hematol.34:1106-1114(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
4.

"Chemerin--a new adipokine that modulates adipogenesis via its own receptor."
Roh S.G. , Song S.H. , Choi K.C. , Katoh K. , Wittamer V. , Parmentier M. , Sasaki S.
Biochem. Biophys. Res. Commun.362:1013-1018(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
5.

"Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism."
Goralski K.B. , McCarthy T.C. , Hanniman E.A. , Zabel B.A. , Butcher E.C. , Parlee S.D. , Muruganandan S. , Sinal C.J.
J. Biol. Chem.282:28175-28188(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
6.

"Chemerin enhances insulin signaling and potentiates insulin-stimulated glucose uptake in 3T3-L1 adipocytes."
Takahashi M. , Takahashi Y. , Takahashi K. , Zolotaryov F.N. , Hong K.S. , Kitazawa R. , Iida K. , Okimura Y. , Kaji H. , Kitazawa S. , Kasuga M. , Chihara K.
FEBS Lett.582:573-578(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
7.

"Mouse ChemR23 is expressed in dendritic cell subsets and macrophages, and mediates an anti-inflammatory activity of chemerin in a lung disease model."
Luangsay S. , Wittamer V. , Bondue B. , De Henau O. , Rouger L. , Brait M. , Franssen J.D. , de Nadai P. , Huaux F. , Parmentier M.
J. Immunol.183:6489-6499(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY

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