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Index > Protein center > Ncapd2(Gene name) > Mouse
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  • Ncapd2 (Gene name),
  • Condensin complex subunit 1 (Protein name ),  CND1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Ncapd2(Capd2;Cnap1;Kiaa0159);
    Protein name:
    Condensin complex subunit 1;
    Alternative:
    Chromosome-associated protein D2(mCAP-D2);Chromosome condensation-related SMC-associated protein 1;XCAP-D2 homolog;Non-SMC condensin I complex subunit D2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and NCAPG. Interacts with histones H1 and H3.
    Function:
    Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain.
    Subcellular Location:
    Nucleus Cytoplasm Chromosome In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
    Protein Attributes:
    Sequence length:
    1392
    Sequence:
    50:
    MSPHNFEFHL | PLSPEELLKS | GGVNQYVVRE | VLPVKHLSSQ | LRAFQSAFRA | 
    100:
    QGPLAILEHF | DTVYSILHHF | RSIEPGLKED | TLEFLKKVVS | RHSQELSSIL | 
    150:
    DDAALSGSDR | SAHLNALKMN | CYALIRLLES | FENMTSQTSL | IDLDIGGKGK | 
    200:
    RARAKATLGF | DWEEERQPVL | QLLTQLLQLD | IRHLWNHSAI | EEEFVSLVTG | 
    250:
    CCYRLLENPT | ISHQKNRSTK | EAIAHLLGVA | LVRYNHMLSA | TVKIIQMLQH | 
    300:
    FEHLPPVLVT | AVSLWATDYG | MKSIVGEIVR | EIGQKCPQEL | SRDTAGAKGF | 
    350:
    AAFLTELAER | IPAVLMANMC | ILLDHLDGEN | YMMRNAVLAA | IAEMVLQVLN | 
    400:
    GDQLEESARE | TRDQFLDILQ | AHGHDVNSFV | RSRVLQLFAR | IVQQKALPLT | 
    450:
    RFQAVVALAV | GRLADKSVLV | CKNAIQLLAS | FLANNPFSCK | LSDIDLAGPL | 
    500:
    QKEIQKLQEM | RAQRRSAAAT | AALDPEEEWD | AMLPELKSTL | QQLLKLPQEE | 
    550:
    GDHQIADAET | AEEVKGRIRQ | LLAKASYKQA | IVLTREATSH | FQESEPFSHT | 
    600:
    EPEENSFLNL | LGLIFKGPEA | STQDSHGDTD | PGLTGSKDSP | SVPEPEGSQS | 
    650:
    NDELVKQEML | VQYLQDAYGF | SQKITEAIGI | ISKMMYENTT | TVVQEVIEFF | 
    700:
    VMVFQFGVPQ | ALFGVRRMLP | LIWSKEPGVR | EAVLNAYRQL | YLNPKGDSAR | 
    750:
    AKAQTLIHNL | SLLLVDASVG | TIQCLEEILC | EFVQKDEVKP | AVIQLLWERA | 
    800:
    TEKVPSSPLE | RCSSVMLLGM | MARGKPEIVG | SNLDALVRVG | LDEKSPQDYR | 
    850:
    LAQQVCLAIA | NISDRRKPSL | GERHPPFRLP | QEHRLFERLQ | DMVTKGFAHP | 
    900:
    DPLWIPFKEV | AVTLTYQLAE | SPDVLCAQML | QGCAKQVLEK | LEKNATEADP | 
    950:
    KETAPRLPTF | LLMNLLSLAG | DVALQQLVHL | EQAVSGELGR | RRVLREEQEH | 
    1000:
    RAKEPKEKTA | SSETTMEEEL | GLVGGATADD | TEAELIRSIC | EKELLDGNQV | 
    1050:
    LAAFVPLLLK | VCNNPGLYSN | PELCAAASLA | LGKFCMISAP | FCDSQLRLLF | 
    1100:
    TMLEKSSLPT | VRSNLMVATG | DLAIRFPNLV | DPWTPHLYAR | LRDPAQQVRK | 
    1150:
    TAGLVMTHLI | LKDMVKVKGQ | VSEMAVLLID | PVPQIAALAK | NFFNELSHKG | 
    1200:
    NAIYNLLPDI | ISRLSDPEGG | VEEEPFHTIM | KQLLSYITKD | KQTESLVEKL | 
    1250:
    CQRFRTARTE | RQYRDLAYCM | SQLPLTERGL | QKMLDNFECF | GDKLLDESVF | 
    1300:
    SAFLSIVGKL | RRGAKPEGKA | IIDEFEQKLR | ACHTRGMDGI | EEFETGQGGS | 
    1350:
    QRALSAKKPS | AVSRLQPLTS | VDSDNDFVTP | KPRRTKPGRP | QTQQRKKSQR | 
    1392:
    KAKVVFLSDE | SSEDELSAEM | TEEETPKRTT | PIRRASGRRH | RS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    UniGene:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Condensin complex subunit 1
    ELISA Kit for Mouse Condensin complex subunit 1
    CLIA Kit for Mouse Condensin complex subunit 1
    CLIA Kit for Mouse Condensin complex subunit 1
    Polyclonal Antibody for Mouse Condensin complex subunit 1
    Polyclonal Antibody for Mouse Condensin complex subunit 1
    Monoclonal Antibody for Mouse Condensin complex subunit 1
    Monoclonal Antibody for Mouse Condensin complex subunit 1
    Protein for Mouse Condensin complex subunit 1
    Protein for Mouse Condensin complex subunit 1

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Nagase T. , Ohara O. , Koga H.
      DNA Res.10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Embryonic tail.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      strain: C57BL/6.
      strain: FVB/N.
      tissue: Mammary tumor.
      tissue: Retina.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 577-1392 (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Embryo.
    4. 4.
      "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
      Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
      Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1300;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
    5. 5.
      "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
      Sweet S.M. , Bailey C.M. , Cunningham D.L. , Heath J.K. , Cooper H.J.
      Mol. Cell. Proteomics8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1320 AND SER-1323;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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