Ncaph ELISA Kit for Mouse(Mus musculus) | EIAab.comNcaph ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Ncaph(Gene name) > Mouse

Ncaph (Gene name),

Condensin complex subunit 2 (Protein name ), CND2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Ncaph(Brrn;Brrn1;Caph);

Protein name:

Condensin complex subunit 2;

Alternative:

Chromosome-associated protein H(mCAP-H);Barren homolog protein 1;XCAP-H homolog;Non-SMC condensin I complex subunit H;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and NCAPG.

Function:

Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Subcellular Location:

Nucleus Cytoplasm Chromosome In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.

Protein Attributes:

Sequence length:

731

Sequence:

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