Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > CNGA1(Gene name) > Human
  • Add your favorite
  • CNGA1 (Gene name),
  • cGMP-gated cation channel alpha-1 (Protein name ),  CNGA1_HUMAN from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    CNGA1(CNCG;CNCG1);
    Protein name:
    cGMP-gated cation channel alpha-1;
    Alternative:
    Cyclic nucleotide-gated channel alpha-1(CNG channel alpha-1;CNG-1;CNG1);Cyclic nucleotide-gated cation channel 1;Rod photoreceptor cGMP-gated channel subunit alpha;Cyclic nucleotide-gated channel, photoreceptor;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotetramer or higher oligomer. Forms heterooligomeric complex with CNG4.
    Function:
    Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    690
    Sequence:
    50:
    MKLSMKNNII | NTQQSFVTMP | NVIVPDIEKE | IRRMENGACS | SFSEDDDSAS | 
    100:
    TSEESENENP | HARGSFSYKS | LRKGGPSQRE | QYLPGAIALF | NVNNSSNKDQ | 
    150:
    EPEEKKKKKK | EKKSKSDDKN | ENKNDPEKKK | KKKDKEKKKK | EEKSKDKKEE | 
    200:
    EKKEVVVIDP | SGNTYYNWLF | CITLPVMYNW | TMVIARACFD | ELQSDYLEYW | 
    250:
    LILDYVSDIV | YLIDMFVRTR | TGYLEQGLLV | KEELKLINKY | KSNLQFKLDV | 
    300:
    LSLIPTDLLY | FKLGWNYPEI | RLNRLLRFSR | MFEFFQRTET | RTNYPNIFRI | 
    350:
    SNLVMYIVII | IHWNACVFYS | ISKAIGFGND | TWVYPDINDP | EFGRLARKYV | 
    400:
    YSLYWSTLTL | TTIGETPPPV | RDSEYVFVVV | DFLIGVLIFA | TIVGNIGSMI | 
    450:
    SNMNAARAEF | QARIDAIKQY | MHFRNVSKDM | EKRVIKWFDY | LWTNKKTVDE | 
    500:
    KEVLKYLPDK | LRAEIAINVH | LDTLKKVRIF | ADCEAGLLVE | LVLKLQPQVY | 
    550:
    SPGDYICKKG | DIGREMYIIK | EGKLAVVADD | GVTQFVVLSD | GSYFGEISIL | 
    600:
    NIKGSKAGNR | RTANIKSIGY | SDLFCLSKDD | LMEALTEYPD | AKTMLEEKGK | 
    650:
    QILMKDGLLD | LNIANAGSDP | KDLEEKVTRM | EGSVDLLQTR | FARILAEYES | 
    690:
    MQQKLKQRLT | KVEKFLKPLI | DTEFSSIEGP | GAESGPIDST | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    MIM:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human cGMP-gated cation channel alpha-1
    ELISA Kit for Human cGMP-gated cation channel alpha-1
    ELISA Kit for Human cGMP-gated cation channel alpha-1
    ELISA Kit for Human cGMP-gated cation channel alpha-1
    ELISA Kit for Human cGMP-gated cation channel alpha-1
    CLIA Kit for Human cGMP-gated cation channel alpha-1
    CLIA Kit for Human cGMP-gated cation channel alpha-1
    CLIA Kit for Human cGMP-gated cation channel alpha-1
    CLIA Kit for Human cGMP-gated cation channel alpha-1
    CLIA Kit for Human cGMP-gated cation channel alpha-1
    Polyclonal Antibody for Human cGMP-gated cation channel alpha-1
    Polyclonal Antibody for Human cGMP-gated cation channel alpha-1
    Polyclonal Antibody for Human cGMP-gated cation channel alpha-1
    Polyclonal Antibody for Human cGMP-gated cation channel alpha-1
    Polyclonal Antibody for Human cGMP-gated cation channel alpha-1
    Monoclonal Antibody for Human cGMP-gated cation channel alpha-1
    Monoclonal Antibody for Human cGMP-gated cation channel alpha-1
    Monoclonal Antibody for Human cGMP-gated cation channel alpha-1
    Monoclonal Antibody for Human cGMP-gated cation channel alpha-1
    Monoclonal Antibody for Human cGMP-gated cation channel alpha-1
    Protein for Human cGMP-gated cation channel alpha-1
    Protein for Human cGMP-gated cation channel alpha-1
    Protein for Human cGMP-gated cation channel alpha-1
    Protein for Human cGMP-gated cation channel alpha-1
    Protein for Human cGMP-gated cation channel alpha-1

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Primary structure and chromosomal localization of human and mouse rod photoreceptor cGMP-gated cation channel."
      Pittler S.J. , Lee A.K. , Altherr M.R. , Howard T.A. , Seldin M.F. , Hurwitz R.L. , Wasmuth J.J. , Baehr W.
      J. Biol. Chem.267:6257-6262(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Retina.
    2. 2.
      "Human rod photoreceptor cGMP-gated channel: amino acid sequence, gene structure, and functional expression."
      Dhallan R.S. , Macke J.P. , Eddy R.L. , Shows T.B. , Reed R.R. , Yau K.-W. , Nathans J.
      J. Neurosci.12:3248-3256(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Retina.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Spleen.
    4. 4.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "Expression of cyclic nucleotide-gated cation channels in non-sensory tissues and cells."
      Distler M. , Biel M. , Flockerzi V. , Hofmann F.
      Neuropharmacology33:1275-1282(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 317-577
    7. 7.
      "Mutations in the gene encoding the alpha subunit of the rod cGMP-gated channel in autosomal recessive retinitis pigmentosa."
      Dryja T.P. , Finn J.T. , Peng Y.-W. , McGee T.L. , Berson E.L. , Yau K.-W.
      Proc. Natl. Acad. Sci. U.S.A.92:10177-10181(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT RP49 PHE-320;VARIANTS GLN-32 AND ASN-118
    8. 8.
      "Autosomal recessive retinitis pigmentosa in a Pakistani family mapped to CNGA1 with identification of a novel mutation."
      Zhang Q. , Zulfiqar F. , Riazuddin S.A. , Xiao X. , Ahmad Z. , Riazuddin S. , Hejtmancik J.F.
      Mol. Vis.10:884-889(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN RP49
    Product Feedback Wall
    Hot Genes
    Atf2 ASPRO ACE ALCAM C19orf80 Trap1a Gdf5
    Top Searches
    Ubiquitin-protein ligase metalloproteinase Ubiquitin ELISA Alpha Tumor necrosis Asprosin TRAP1A
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.com.cn

    Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    鄂ICP备10015095号-1

    鄂公网安备 42018502005535号

    Twitter