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Index > Protein center > CNN1(Gene name) > Human
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  • CNN1 (Gene name),
  • Calponin-1 (Protein name ),  CNN1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    CNN1;
    Protein name:
    Calponin-1;
    Alternative:
    Calponin H1, smooth muscle;Basic calponin;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1.
    Function:
    Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    297
    Sequence:
    50:
    MSSAHFNRGP | AYGLSAEVKN | KLAQKYDHQR | EQELREWIEG | VTGRRIGNNF | 
    100:
    MDGLKDGIIL | CEFINKLQPG | SVKKINESTQ | NWHQLENIGN | FIKAITKYGV | 
    150:
    KPHDIFEAND | LFENTNHTQV | QSTLLALASM | AKTKGNKVNV | GVKYAEKQER | 
    200:
    KFEPGKLREG | RNIIGLQMGT | NKFASQQGMT | AYGTRRHLYD | PKLGTDQPLD | 
    250:
    QATISLQMGT | NKGASQAGMT | APGTKRQIFE | PGLGMEHCDT | LNVSLQMGSN | 
    297:
    KGASQRGMTV | YGLPRQVYDP | KYCLTPEYPE | LGEPAHNHHA | HNYYNSA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    MIM:
    Pfam:
    KEGG:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Calponin-1
    Cat.:
    E1998h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Human Calponin-1
    Cat.:
    E1998p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Calponin-1
    Cat.:
    E1998m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Calponin-1
    Cat.:
    E1998r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Calponin-1
    Cat.:
    E1998c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Calponin-1
    Cat.:
    E1998b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Calponin-1
    Cat.:
    U1998c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Calponin-1
    Cat.:
    U1998b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Calponin-1
    Cat.:
    U1998m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Calponin-1
    Cat.:
    U1998h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Calponin-1
    Cat.:
    U1998p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Calponin-1
    Cat.:
    U1998r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Calponin-1
    Cat.:
    P1998Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Calponin-1
    Polyclonal Antibody for Human Calponin-1
    Polyclonal Antibody for Human Calponin-1
    Cat.:
    P1998Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Calponin-1
    Polyclonal Antibody for Human Calponin-1
    Cat.:
    P1998Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Calponin-1
    Monoclonal Antibody for Human Calponin-1
    Monoclonal Antibody for Human Calponin-1
    Monoclonal Antibody for Human Calponin-1
    Monoclonal Antibody for Human Calponin-1
    Monoclonal Antibody for Human Calponin-1
    Protein for Human Calponin-1
    Protein for Human Calponin-1
    Protein for Human Calponin-1
    Protein for Human Calponin-1
    Protein for Human Calponin-1
    Protein for Human Calponin-1

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    References
    1. 1.
      "Molecular cloning and gene mapping of human basic and acidic calponins."
      Maguchi M. , Nishida W. , Kohara K. , Kuwano A. , Kondo I. , Hiwada K.
      Biochem. Biophys. Res. Commun.217:238-244(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Aorta.
    2. 2.
      "Expression, genomic structure and high resolution mapping to 19p13.2 of the human smooth muscle cell calponin gene."
      Miano J.M. , Krahe R. , Garcia E. , Elliott J.M. , Olson E.N.
      Gene197:215-224(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      Takahashi K.
      Submitted (1997-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Aorta.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Pericardium.
      tissue: Small intestine.
    5. 5.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
      tissue: Testis.
    8. 8.
      "Systematic RLGS-M screening and identification of genes on chromosome 21 regulated by the dosage compensation in Down syndrome."
      Kuromitsu J. , Hayashizaki Y.
      Submitted (1996-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 17-297 (ISOFORM 1)
      tissue: Placenta.
    9. 9.
      Takahashi K.
      Submitted (1996-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-21
    10. 10.
      "Solution structure of the CH domain of human calponin 1."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2005-08) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 20-142
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