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Index > Protein center > CNN2(Gene name) > Human
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  • CNN2 (Gene name),
  • Calponin-2 (Protein name ),  CNN2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CNN2;
    Protein name:
    Calponin-2;
    Alternative:
    Neutral calponin;Calponin H2, smooth muscle;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    309
    Sequence:
    50:
    MSSTQFNKGP | SYGLSAEVKN | RLLSKYDPQK | EAELRTWIEG | LTGLSIGPDF | 
    100:
    QKGLKDGTIL | CTLMNKLQPG | SVPKINRSMQ | NWHQLENLSN | FIKAMVSYGM | 
    150:
    NPVDLFEAND | LFESGNMTQV | QVSLLALAGK | AKTKGLQSGV | DIGVKYSEKQ | 
    200:
    ERNFDDATMK | AGQCVIGLQM | GTNKCASQSG | MTAYGTRRHL | YDPKNHILPP | 
    250:
    MDHSTISLQM | GTNKCASQVG | MTAPGTRRHI | YDTKLGTDKC | DNSSMSLQMG | 
    300:
    YTQGANQSGQ | VFGLGRQIYD | PKYCPQGTVA | DGAPSGTGDC | PDPGEVPEYP | 
    309:
    PYYQEEAGY
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    MIM:
    Pfam:
    SMR:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Calponin-2
    Cat.:
    E14008h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Calponin-2
    MSDS:
    Please sign in first.
    ELISA Kit for Human Calponin-2
    MSDS:
    Please sign in first.
    ELISA Kit for Human Calponin-2
    Cat.:
    E14008m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Calponin-2
    Cat.:
    U14008m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Calponin-2
    MSDS:
    Please sign in first.
    CLIA Kit for Human Calponin-2
    MSDS:
    Please sign in first.
    CLIA Kit for Human Calponin-2
    Cat.:
    U14008h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human Calponin-2
    Polyclonal Antibody for Human Calponin-2
    Polyclonal Antibody for Human Calponin-2
    Polyclonal Antibody for Human Calponin-2
    Monoclonal Antibody for Human Calponin-2
    Monoclonal Antibody for Human Calponin-2
    Monoclonal Antibody for Human Calponin-2
    Monoclonal Antibody for Human Calponin-2
    Protein for Human Calponin-2
    Protein for Human Calponin-2
    Protein for Human Calponin-2
    Protein for Human Calponin-2

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    Precision
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    Linearity
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    References
    1. 1.
      "Molecular cloning and characterization of human non-smooth muscle calponin."
      Masuda H. , Tanaka K. , Takagi M. , Ohgami K. , Sakamaki T. , Shibata N. , Takahashi K.
      J. Biochem.120:415-424(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Heart.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Uterus.
    3. 3.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    6. 6.
      "A unique downregulation of h2-calponin gene expression in Down syndrome: a possible attenuation mechanism for fetal survival by methylation at the CpG island in the trisomic chromosome 21."
      Kuromitsu J. , Yamashita H. , Kataoka H. , Takahara T. , Muramatsu M. , Sekine T. , Okamoto N. , Furuichi Y. , Hayashizaki Y.
      Mol. Cell. Biol.17:707-712(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-202 (ISOFORM 1)
      tissue: Placenta.
    7. 7.
      "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
      Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
      Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-21
      tissue: Platelet.
    8. 8.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2; LYS-8 AND LYS-25;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      "Solution structure of the CH domain of human calponin-2."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2005-08) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 20-152
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