Subunit of the CCR4-NOT core complex that contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8. Binds CNOT1 via its C-terminus. Binds E2 ubiquitin ligases via its RING domain. Interacts (via RING domain) with UBE2D2.
Function:
Has E3 ubiquitin ligase activity. The CCR4-NOT complex functions as general transcription regulation complex.
ELISA Kit for Mouse CCR4-NOT transcription complex subunit 4
ELISA Kit for Mouse CCR4-NOT transcription complex subunit 4
CLIA Kit for Mouse CCR4-NOT transcription complex subunit 4
CLIA Kit for Mouse CCR4-NOT transcription complex subunit 4
Polyclonal Antibody for Mouse CCR4-NOT transcription complex subunit 4
Polyclonal Antibody for Mouse CCR4-NOT transcription complex subunit 4
Monoclonal Antibody for Mouse CCR4-NOT transcription complex subunit 4
Monoclonal Antibody for Mouse CCR4-NOT transcription complex subunit 4
Protein for Mouse CCR4-NOT transcription complex subunit 4
Protein for Mouse CCR4-NOT transcription complex subunit 4
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Isolation and characterization of human and murine homologues of yeast NOT4 gene." Chiang P.-W.
Submitted (1996-09) to the EMBL/GenBank/DDBJ databases
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Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
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Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
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Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
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Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-71;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]