CNOT7 ELISA Kit for Human(Homo sapiens) | EIAab.comCNOT7 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CNOT7(Gene name) > Human

CNOT7 (Gene name),

CCR4-NOT transcription complex subunit 7 (Protein name ), CNOT7_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CNOT7(CAF1);

Protein name:

CCR4-NOT transcription complex subunit 7;

Alternative:

CCR4-associated factor 1(CAF-1);BTG1-binding factor 1;Caf1a;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with TOB1. Interacts with NANOS2.

Function:

Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression.

Subcellular Location:

Nucleus Cytoplasm P-body NANOS2 promotes its localization to P-body.

Protein Attributes:

Sequence length:

285

Sequence:

50:

100:

150:

200:

250:

285:

DDAKYCGHLY | GLGSGSSYVQ | NGTGNAYEEE | ANKQS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9UIV1

Pfam:

PF04857

MIM:

604913

SMR:

Q9UIV1

UniGene:

Hs.645009

KEGG:

hsa:29883

STRING:

9606.ENSP00000355279

Uniprot:

Q9UIV1

FOR

ELISA Kit for Human CCR4-NOT transcription complex subunit 7

CLIA Kit for Human CCR4-NOT transcription complex subunit 7

Polyclonal Antibody for Human CCR4-NOT transcription complex subunit 7

Monoclonal Antibody for Human CCR4-NOT transcription complex subunit 7

Protein for Human CCR4-NOT transcription complex subunit 7

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Human carbon catabolite repressor protein (CCR4)-associative factor 1: cloning, expression and characterization of its interaction with the B-cell translocation protein BTG1."
Bogdan J.A. , Adams-Burton C. , Pedicord D.L. , Sukovich D.A. , Benfield P.A. , Corjay M.H. , Stoltenborg J.K. , Dicker I.B.
Biochem. J.336:471-481(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.

"Cloning and expression of a new human cDNA homology to mouse mCAF1 protein mRNA."
Wan Y.Z. , Yu L. , Zhang H.L. , Liu Q. , Chen S.Y. , Zhao S.Y.
Submitted (2003-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue: Embryo.
tissue: Placenta.
4.

"DNA sequence and analysis of human chromosome 8."
Nusbaum C. , Mikkelsen T.S. , Zody M.C. , Asakawa S. , Taudien S. , Garber M. , Kodira C.D. , Schueler M.G. , Shimizu A. , Whittaker C.A. , Chang J.L. , Cuomo C.A. , Dewar K. , FitzGerald M.G. , Yang X. , Allen N.R. , Anderson S. , Asakawa T. , more...
Nature439:331-335(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Prostate.
tissue: Testis.
7.

"Conservation of the deadenylase activity of proteins of the Caf1 family in human."
Bianchin C. , Mauxion F. , Sentis S. , Seraphin B. , Corbo L.
RNA11:487-494(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY
8.

"Human Ccr4-Not complexes contain variable deadenylase subunits."
Lau N.C. , Kolkman A. , van Schaik F.M. , Mulder K.W. , Pijnappel W.W. , Heck A.J. , Timmers H.T.
Biochem. J.422:443-453(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE CCR4-NOT COMPLEX;COMPOSITION OF THE CCR4-NOT COMPLEX
9.

"The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation."
Aslam A. , Mittal S. , Koch F. , Andrau J.C. , Winkler G.S.
Mol. Biol. Cell20:3840-3850(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
10.

"Translational repression by deadenylases."
Cooke A. , Prigge A. , Wickens M.
J. Biol. Chem.285:28506-28513(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY
11.

"CCR4-NOT deadenylates mRNA associated with complexes in human cells."
Piao X. , Zhang X. , Wu L. , Belasco J.G.
Mol. Cell. Biol.30:1486-1494(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
12.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex."
Doidge R. , Mittal S. , Aslam A. , Winkler G.S.
PLoS ONE7:E51331-E51331(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH TOB1 AND BTG2
14.

"Structural basis for the antiproliferative activity of the Tob-hCaf1 complex."
Horiuchi M. , Takeuchi K. , Noda N. , Muroya N. , Suzuki T. , Nakamura T. , Kawamura-Tsuzuku J. , Takahasi K. , Yamamoto T. , Inagaki F.
J. Biol. Chem.284:13244-13255(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 11-262 IN COMPLEX WITH TOB1;CATALYTIC ACTIVITY;COFACTOR;MUTAGENESIS OF ASP-40; GLU-42; ASP-161; HIS-225 AND ASP-230
15.

"The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex."
Petit A.P. , Wohlbold L. , Bawankar P. , Huntzinger E. , Schmidt S. , Izaurralde E. , Weichenrieder O.
Nucleic Acids Res.40:11058-11072(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 1-285 IN COMPLEX WITH CNOT1;MUTAGENESIS OF GLU-138; MET-141; THR-142 AND GLU-149

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