CNTN1 ELISA Kit for Human(Homo sapiens) | EIAab.comCNTN1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CNTN1(Gene name) > Human

CNTN1 (Gene name),

Contactin-1 (Protein name ), CNTN1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CNTN1;

Protein name:

Contactin-1;

Alternative:

Neural cell surface protein F3;Glycoprotein gp135;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer. Interacts with CNTNAP1 in cis form. Binds to the carbonic-anhydrase like domain of protein-tyrosine phosphatase zeta. Interacts with NOTCH1 and TNR.

Function:

Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth.

Subcellular Location:

Isoform 2 Cell membrane Lipid-anchor GPI-anchor Extracellular side

Protein Attributes:

Sequence length:

1018

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1018:

SLLGLLLPAF | GILVYLEF

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.143434

KEGG:

hsa:1272

MIM:

600016

String:

Q12860

Pfam:

PF00041

SMR:

Q12860

STRING:

9606.ENSP00000325660

Uniprot:

Q12860

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ELISA Kit for Human Contactin-1

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ELISA Kit for Human Contactin-1

Cat.:

E15020h

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96T

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ELISA Kit for Human Contactin-1

Cat.:

E15020r

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Manual:

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ELISA Kit for Human Contactin-1

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ELISA Kit for Human Contactin-1

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CLIA Kit for Human Contactin-1

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CLIA Kit for Human Contactin-1

Cat.:

U15020r

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Packing:

96T

CLIA Kit for Human Contactin-1

MSDS:

Please sign in first.

CLIA Kit for Human Contactin-1

MSDS:

Please sign in first.

CLIA Kit for Human Contactin-1

Cat.:

U15020h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human Contactin-1

Monoclonal Antibody for Human Contactin-1

Protein for Human Contactin-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Identification and characterization of the human cell adhesion molecule contactin."
Reid R.A. , Bronson D.D. , Young K.M. , Hemperly J.J.
Brain Res. Mol. Brain Res.21:1-8(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
tissue: Neuroblastoma.
2.

"Molecular cloning and in situ localization of the human contactin gene (CNTN1) on chromosome 12q11-q12."
Berglund E.O. , Ranscht B.
Genomics21:571-582(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
tissue: Brain.
3.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
tissue: Amygdala.
tissue: Cerebellum.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
tissue: Brain.
5.

"Isolation and characterization of a membrane glycoprotein from human brain with sequence similarities to cell adhesion proteins from chicken and mouse."
Berglund E. , Stigbrand T. , Carlsson S.R.
Eur. J. Biochem.197:549-554(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-40 AND 679-693 (ISOFORM 1);SUBUNIT;TISSUE SPECIFICITY
tissue: Brain cortex.
6.

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-494
tissue: Plasma.
7.

"A strategy for precise and large scale identification of core fucosylated glycoproteins."
Jia W. , Lu Z. , Fu Y. , Wang H.P. , Wang L.H. , Chi H. , Yuan Z.F. , Zheng Z.B. , Song L.N. , Han H.H. , Liang Y.M. , Wang J.L. , Cai Y. , Zhang Y.K. , Deng Y.L. , Ying W.T. , He S.M. , Qian X.H.
Mol. Cell. Proteomics8:913-923(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-494
8.

"The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules."
Bouyain S. , Watkins D.J.
Proc. Natl. Acad. Sci. U.S.A.107:2443-2448(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PTPRZ1
9.

"Solution structures of the FN3 domain of human contactin 1."
RIKEN structural genomics initiative (RSGI)
Submitted (2007-08) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 791-903
10.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] HIS-794
11.

"Mutations in contactin-1, a neural adhesion and neuromuscular junction protein, cause a familial form of lethal congenital myopathy."
Compton A.G. , Albrecht D.E. , Seto J.T. , Cooper S.T. , Ilkovski B. , Jones K.J. , Challis D. , Mowat D. , Ranscht B. , Bahlo M. , Froehner S.C. , North K.N.
Am. J. Hum. Genet.83:714-724(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN MYPCN

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