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Index > Protein center > Cntn6(Gene name) > Mouse
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  • Cntn6 (Gene name),
  • Contactin-6 (Protein name ),  CNTN6_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cntn6;
    Protein name:
    Contactin-6;
    Alternative:
    Neural recognition molecule NB-3(mNB-3);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus (By similarity). Involved in motor coordination.
    Subcellular Location:
    Cell membrane Lipid-anchor GPI-anchor
    Protein Attributes:
    Sequence length:
    1028
    Sequence:
    50:
    MRLLWKLVIL | LPLINSCAGE | GRFSRPIFIQ | EPQDVIFPLD | LSRSEIILTC | 
    100:
    TANGYPSPHY | RWKQNGTDID | FGMTYHYRLD | GGSLAISSPR | TDQDIGIYQC | 
    150:
    LATNPVGTIL | SRKAKLQFAY | IEDFETKTRS | TVSVREGQGV | VLLCGPPPHF | 
    200:
    GELSYAWTFN | DSPLYVQEDK | RRFVSQDTGN | LYFAKVEPSD | VGNYTCFVTN | 
    250:
    KEAHRSVQGP | PTPLVLRTDG | VMGEYEPKIE | VRFPETIQAA | KDSSIKLECF | 
    300:
    ALGNPVPDIS | WKRLDGSPMP | GKIKYSKSQA | ILEIPKFQQE | DEGFYECIAG | 
    350:
    NLRGRNLAKG | QLIFYAPPEW | EQKIQNTYLS | IYDSLFWECK | ASGNPNPSYT | 
    400:
    WLKNGQRLNT | EERIQIENGT | LIITMLNISD | SGIYQCAAEN | KYQTIYANAE | 
    450:
    LRVLASAPDF | SKNPIKKISV | VQVGGDISIE | CKPNAFPKAS | ISWKRGTENL | 
    500:
    KQSKRVLFLE | DGSLKICNVT | RADAGSYTCV | ATNQFGNGKS | SGGLVVKERT | 
    550:
    IITVPPSKMD | VTVGESIVLP | CQVSHDPTME | VLFVWYFNGD | IIDLKKGVAH | 
    600:
    FERIGGESVG | DLMIRNIQLG | HSGKYLCTVQ | TTLERLSAVA | DIIVRGPPGP | 
    650:
    PEDVKVEHIS | STTSQLSWRP | GPDNNSPIQI | FTIQTRTPFS | VGWQAVATVP | 
    700:
    EILNGQTYNA | TVVGLSPWVE | YEFRVVAGNN | IGIGEPSKPS | ELLRTKASVP | 
    750:
    NVAPGNINGG | GGSRSELVIT | WEAIPEELQN | GEGFGYIVMF | RPVGTTAWMK | 
    800:
    ERVALVESSK | FIYRNESIMP | LSPFEVKVGV | YNNEGEGSLS | TVTIVYSGED | 
    850:
    EPQLAPRGTS | VQSFSASEME | VSWNAIAWNR | NTGRVLGYEV | LYWTDNSKES | 
    900:
    MIGKIRVSGN | VTTKNITGLR | ANTIYFASVR | AYNTAGTGPS | SLPVNVTTKK | 
    950:
    SPPSQPPANI | AWKLSNSKLC | LNWEHVKTME | NESEVLGYKI | LYRQNRQSKT | 
    1000:
    HILETNNTSA | ELLVPFEEDY | LIEIRTVSDG | GDGSSSEEIR | IPKMSSLSST | 
    1028:
    GVQISKPSTQ | SLSMVGVFYC | FAIHPLSR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    SMR:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Contactin-6
    ELISA Kit for Mouse Contactin-6
    ELISA Kit for Mouse Contactin-6
    CLIA Kit for Mouse Contactin-6
    CLIA Kit for Mouse Contactin-6
    CLIA Kit for Mouse Contactin-6
    Polyclonal Antibody for Mouse Contactin-6
    Polyclonal Antibody for Mouse Contactin-6
    Polyclonal Antibody for Mouse Contactin-6
    Monoclonal Antibody for Mouse Contactin-6
    Monoclonal Antibody for Mouse Contactin-6
    Monoclonal Antibody for Mouse Contactin-6
    Protein for Mouse Contactin-6
    Protein for Mouse Contactin-6
    Protein for Mouse Contactin-6

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Expression and regulation of a gene encoding neural recognition molecule NB-3 of the contactin/F3 subgroup in mouse brain."
      Lee S. , Takeda Y. , Kawano H. , Hosoya H. , Nomoto M. , Fujimoto D. , Takahashi N. , Watanabe K.
      Gene245:253-266(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
      strain: 129/SvJ.
      tissue: Brain.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Head.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6.
      tissue: Eye.
    4. 4.
      "Impaired motor coordination in mice lacking neural recognition molecule NB-3 of the contactin/F3 subgroup."
      Takeda Y. , Akasaka K. , Lee S. , Kobayashi S. , Kawano H. , Murayama S. , Takahashi N. , Hashimoto K. , Kano M. , Asano M. , Sudo K. , Iwakura Y. , Watanabe K.
      J. Neurobiol.56:252-265(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
    5. 5.
      "The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules."
      Bouyain S. , Watkins D.J.
      Proc. Natl. Acad. Sci. U.S.A.107:2443-2448(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PTPRG
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