Protein name:
Complement C3 alpha chain ;
Alternative:
Organism:
Rabbit (Oryctolagus cuniculus).
General Annotation
Sub Unit:
C3 precursor is first processed by the removal of 4 Arg residues, forming two chains, beta and alpha, linked by a disulfide bond. C3 convertase activates C3 by cleaving the alpha chain, releasing C3a anaphylatoxin and generating C3b (beta chain + alpha' chain). C3dg interacts with CR2 (via the N-terminal Sushi domains 1 and 2). Interacts with VSIG4.
Function:
C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
Subcellular Location:
Secreted
Protein Attributes:
50:
MNKTVAVRTL | DPENLGQGGV | QKEEIPSADI | SDQVPGTESE | TKILLQGTPV |
100:
AQMTEDAIDG | ERLKHLIVTG | SGCGEQNMIA | MTHTVIAVHY | LDHTEQWDKF |
150:
SLEKRQEALE | LIKKGYTQQL | AFKQPNSAYA | AFLNRAPSTW | LTAYVVKVFS |
200:
LAVNLIAIDS | QVLCGAVKWL | IMEKQKPDGV | FQEDAPVIHQ | EMIGGQRNSV |
250:
EKERALTAFV | LIALQEAREI | CEEQVNSLAA | SINKSRDFLA | ANYMNLQRPY |
300:
SVAIAAYAWA | QQDKLRGAFL | NKFLSKAKEK | NRWEEPGQRL | YNVEASSYAL |
350:
LALLLLRDFD | SVPPVVRWLN | EQRYYGGGYG | STQATFMGFQ | ALAQYQTDVP |
400:
DHKDLNMVVS | IQLPSRSSPV | KHRIVWDSAS | LLRSEETKEN | QGFSLTAQGK |
450:
GQGTLSVVTT | YFAKVKGKVT | CKKFDLRVNI | KTAPETVKKP | QDAKSTMILG |
500:
HCTRYLGDED | ATMSILDISM | MTGFVPDTDD | LNLLSTGVDR | YISKYELNKA |
550:
FSNKNTLIIY | LDKISHSREE | CLAFKVHQYF | NVGLIQPGAV | KVYSYYNLEE |
600:
TCTQFYHPEK | EDGMLSKLCH | KEMCRCAEEN | CFMQQLDEKI | TLNDRLDKAC |
650:
EPGLDYVYKT | KLVQVERADD | FDEYLMVVEN | TIKSGSDEVQ | AGQPAPFISH |
700:
IKCRDALKLK | DGKHYLMWGL | SSDPVGEKPN | TSYIIGKDTW | VEFWPEKEEC |
726:
QDEENQKHCE | DLGAFAESMV | VFGCPN
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Pig
Rat
Bovine
Rabbit
ELISA Kit for Rabbit Complement C3 alpha chain
ELISA Kit for Rabbit Complement C3 alpha chain
ELISA Kit for Rabbit Complement C3 alpha chain
ELISA Kit for Rabbit Complement C3 alpha chain
ELISA Kit for Rabbit Complement C3 alpha chain
ELISA Kit for Rabbit Complement C3 alpha chain
CLIA Kit for Rabbit Complement C3 alpha chain
CLIA Kit for Rabbit Complement C3 alpha chain
CLIA Kit for Rabbit Complement C3 alpha chain
CLIA Kit for Rabbit Complement C3 alpha chain
CLIA Kit for Rabbit Complement C3 alpha chain
CLIA Kit for Rabbit Complement C3 alpha chain
Polyclonal Antibody for Rabbit Complement C3 alpha chain
Polyclonal Antibody for Rabbit Complement C3 alpha chain
Polyclonal Antibody for Rabbit Complement C3 alpha chain
Polyclonal Antibody for Rabbit Complement C3 alpha chain
Polyclonal Antibody for Rabbit Complement C3 alpha chain
Polyclonal Antibody for Rabbit Complement C3 alpha chain
Monoclonal Antibody for Rabbit Complement C3 alpha chain
Monoclonal Antibody for Rabbit Complement C3 alpha chain
Monoclonal Antibody for Rabbit Complement C3 alpha chain
Monoclonal Antibody for Rabbit Complement C3 alpha chain
Monoclonal Antibody for Rabbit Complement C3 alpha chain
Monoclonal Antibody for Rabbit Complement C3 alpha chain
Protein for Rabbit Complement C3 alpha chain
Protein for Rabbit Complement C3 alpha chain
Protein for Rabbit Complement C3 alpha chain
Protein for Rabbit Complement C3 alpha chain
Protein for Rabbit Complement C3 alpha chain
Protein for Rabbit Complement C3 alpha chain
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]