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Index > Protein center > C3(Gene name) > Rabbit
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  • C3 (Gene name),
  • Complement C3 alpha chain (Protein name ),  CO3_RABIT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    C3;
    Protein name:
    Complement C3 alpha chain;
    Alternative:

    Organism:
    Rabbit (Oryctolagus cuniculus). 
    General Annotation
    Sub Unit:
    C3 precursor is first processed by the removal of 4 Arg residues, forming two chains, beta and alpha, linked by a disulfide bond. C3 convertase activates C3 by cleaving the alpha chain, releasing C3a anaphylatoxin and generating C3b (beta chain + alpha' chain). C3dg interacts with CR2 (via the N-terminal Sushi domains 1 and 2). Interacts with VSIG4.
    Function:
    C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    726
    Sequence:
    50:
    MNKTVAVRTL | DPENLGQGGV | QKEEIPSADI | SDQVPGTESE | TKILLQGTPV | 
    100:
    AQMTEDAIDG | ERLKHLIVTG | SGCGEQNMIA | MTHTVIAVHY | LDHTEQWDKF | 
    150:
    SLEKRQEALE | LIKKGYTQQL | AFKQPNSAYA | AFLNRAPSTW | LTAYVVKVFS | 
    200:
    LAVNLIAIDS | QVLCGAVKWL | IMEKQKPDGV | FQEDAPVIHQ | EMIGGQRNSV | 
    250:
    EKERALTAFV | LIALQEAREI | CEEQVNSLAA | SINKSRDFLA | ANYMNLQRPY | 
    300:
    SVAIAAYAWA | QQDKLRGAFL | NKFLSKAKEK | NRWEEPGQRL | YNVEASSYAL | 
    350:
    LALLLLRDFD | SVPPVVRWLN | EQRYYGGGYG | STQATFMGFQ | ALAQYQTDVP | 
    400:
    DHKDLNMVVS | IQLPSRSSPV | KHRIVWDSAS | LLRSEETKEN | QGFSLTAQGK | 
    450:
    GQGTLSVVTT | YFAKVKGKVT | CKKFDLRVNI | KTAPETVKKP | QDAKSTMILG | 
    500:
    HCTRYLGDED | ATMSILDISM | MTGFVPDTDD | LNLLSTGVDR | YISKYELNKA | 
    550:
    FSNKNTLIIY | LDKISHSREE | CLAFKVHQYF | NVGLIQPGAV | KVYSYYNLEE | 
    600:
    TCTQFYHPEK | EDGMLSKLCH | KEMCRCAEEN | CFMQQLDEKI | TLNDRLDKAC | 
    650:
    EPGLDYVYKT | KLVQVERADD | FDEYLMVVEN | TIKSGSDEVQ | AGQPAPFISH | 
    700:
    IKCRDALKLK | DGKHYLMWGL | SSDPVGEKPN | TSYIIGKDTW | VEFWPEKEEC | 
    726:
    QDEENQKHCE | DLGAFAESMV | VFGCPN
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rabbit Complement C3 alpha chain
    Cat.:
    E0861h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rabbit Complement C3 alpha chain
    Cat.:
    E0861m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rabbit Complement C3 alpha chain
    MSDS:
    Please sign in first.
    ELISA Kit for Rabbit Complement C3 alpha chain
    Cat.:
    E0861r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rabbit Complement C3 alpha chain
    Cat.:
    E0861b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rabbit Complement C3 alpha chain
    MSDS:
    Please sign in first.
    CLIA Kit for Rabbit Complement C3 alpha chain
    Cat.:
    U0861b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rabbit Complement C3 alpha chain
    MSDS:
    Please sign in first.
    CLIA Kit for Rabbit Complement C3 alpha chain
    Cat.:
    U0861r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rabbit Complement C3 alpha chain
    MSDS:
    Please sign in first.
    CLIA Kit for Rabbit Complement C3 alpha chain
    Cat.:
    U0861m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rabbit Complement C3 alpha chain
    Cat.:
    U0861h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rabbit Complement C3 alpha chain
    Polyclonal Antibody for Rabbit Complement C3 alpha chain
    Polyclonal Antibody for Rabbit Complement C3 alpha chain
    Cat.:
    P0861Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rabbit Complement C3 alpha chain
    Cat.:
    P0861Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rabbit Complement C3 alpha chain
    Polyclonal Antibody for Rabbit Complement C3 alpha chain
    Cat.:
    P0861Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rabbit Complement C3 alpha chain
    Monoclonal Antibody for Rabbit Complement C3 alpha chain
    Monoclonal Antibody for Rabbit Complement C3 alpha chain
    Monoclonal Antibody for Rabbit Complement C3 alpha chain
    Monoclonal Antibody for Rabbit Complement C3 alpha chain
    Monoclonal Antibody for Rabbit Complement C3 alpha chain
    Protein for Rabbit Complement C3 alpha chain
    Protein for Rabbit Complement C3 alpha chain
    Cat.:
    R0861h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Rabbit Complement C3 alpha chain
    Protein for Rabbit Complement C3 alpha chain
    Protein for Rabbit Complement C3 alpha chain
    Protein for Rabbit Complement C3 alpha chain

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    References
    1. 1.
      "Nucleotide sequence of cDNA and derived amino acid sequence of rabbit complement component C3 alpha-chain."
      Kusano M. , Choi N.H. , Tomita M. , Yamamoto K. , Migita S. , Sekiya T. , Nishimura S.
      Immunol. Invest.15:365-378(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
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