Protein name:
Collagen alpha-1(IV) chain ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
There are six type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple helix structure with 2 other chains to generate type IV collagen network.
Function:
Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.
Subcellular Location:
Secreted
extracellular space
extracellular matrix
basement membrane
Protein Attributes:
50:
MGPRLSVWLL | LLFAALLLHE | ERSRAAAKGD | CGGSGCGKCD | CHGVKGQKGE |
100:
RGLPGLQGVI | GFPGMQGPEG | PHGPPGQKGD | AGEPGLPGTK | GTRGPPGAAG |
150:
YPGNPGLPGI | PGQDGPPGPP | GIPGCNGTKG | ERGPLGPPGL | PGFSGNPGPP |
200:
GLPGMKGDPG | EILGHVPGTL | LKGERGFPGI | PGMPGSPGLP | GLQGPVGPPG |
250:
FTGPPGPPGP | PGPPGEKGQM | GSSFQGPKGD | KGEQGVSGPP | GVPGQAQVKE |
300:
KGDFAPTGEK | GQKGEPGFPG | VPGYGEKGEP | GKQGPRGKPG | KDGEKGERGS |
350:
PGIPGDSGYP | GLPGRQGPQG | EKGEAGLPGP | PGTVIGTMPL | GEKGDRGYPG |
400:
APGLRGEPGP | KGFPGTPGQP | GPPGFPTPGQ | AGAPGFPGER | GEKGDQGFPG |
450:
VSLPGPSGRD | GAPGPPGPPG | PPGQPGHTNG | IVECQPGPPG | DQGPPGTPGQ |
500:
PGLTGEVGQK | GQKGESCLAC | DTEGLRGPPG | PQGPPGEIGF | PGQPGAKGDR |
550:
GLPGRDGLEG | LPGPQGSPGL | IGQPGAKGEP | GEIFFDMRLK | GDKGDPGFPG |
600:
QPGMPGRAGT | PGRDGHPGLP | GPKGSPGSIG | LKGERGPPGG | VGFPGSRGDI |
650:
GPPGPPGVGP | IGPVGEKGQA | GFPGGPGSPG | LPGPKGEAGK | VVPLPGPPGA |
700:
AGLPGSPGFP | GPQGDRGFPG | TPGRPGIPGE | KGAVGQPGIG | FPGLPGPKGV |
750:
DGLPGEIGRP | GSPGRPGFNG | LPGNPGPQGQ | KGEPGIGLPG | LKGQPGLPGI |
800:
PGTPGEKGSI | GGPGVPGEQG | LTGPPGLQGI | RGDPGPPGVQ | GPAGPPGVPG |
850:
IGPPGAMGPP | GGQGPPGSSG | PPGIKGEKGF | PGFPGLDMPG | PKGDKGSQGL |
900:
PGLTGQSGLP | GLPGQQGTPG | VPGFPGSKGE | MGVMGTPGQP | GSPGPAGTPG |
950:
LPGEKGDHGL | PGSSGPRGDP | GFKGDKGDVG | LPGMPGSMEH | VDMGSMKGQK |
1000:
GDQGEKGQIG | PTGDKGSRGD | PGTPGVPGKD | GQAGHPGQPG | PKGDPGLSGT |
1050:
PGSPGLPGPK | GSVGGMGLPG | SPGEKGVPGI | PGSQGVPGSP | GEKGAKGEKG |
1100:
QSGLPGIGIP | GRPGDKGDQG | LAGFPGSPGE | KGEKGSAGTP | GMPGSPGPRG |
1150:
SPGNIGHPGS | PGLPGEKGDK | GLPGLDGVPG | VKGEAGLPGT | PGPTGPAGQK |
1200:
GEPGSDGIPG | SAGEKGEQGV | PGRGFPGFPG | SKGDKGSKGE | VGFPGLAGSP |
1250:
GIPGVKGEQG | FMGPPGPQGQ | PGLPGTPGHP | VEGPKGDRGP | QGQPGLPGHP |
1300:
GPMGPPGFPG | INGPKGDKGN | QGWPGAPGVP | GPKGDPGFQG | MPGIGGSPGI |
1350:
TGSKGDMGLP | GVPGFQGQKG | LPGLQGVKGD | QGDQGVPGPK | GLQGPPGPPG |
1400:
PYDVIKGEPG | LPGPEGPPGL | KGLQGPPGPK | GQQGVTGSVG | LPGPPGVPGF |
1450:
DGAPGQKGET | GPFGPPGPRG | FPGPPGPDGL | PGSMGPPGTP | SVDHGFLVTR |
1500:
HSQTTDDPLC | PPGTKILYHG | YSLLYVQGNE | RAHGQDLGTA | GSCLRKFSTM |
1550:
PFLFCNINNV | CNFASRNDYS | YWLSTPEPMP | MSMAPISGDN | IRPFISRCAV |
1600:
CEAPAMVMAV | HSQTIQIPQC | PNGWSSLWIG | YSFVMHTSAG | AEGSGQALAS |
1650:
PGSCLEEFRS | APFIECHGRG | TCNYYANAYS | FWLATIERSE | MFKKPTPSTL |
1669:
KAGELRTHVS | RCQVCMRRT
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
ELISA Kit for Mouse Collagen alpha-1(IV) chain
ELISA Kit for Mouse Collagen alpha-1(IV) chain
ELISA Kit for Mouse Collagen alpha-1(IV) chain
ELISA Kit for Mouse Collagen alpha-1(IV) chain
CLIA Kit for Mouse Collagen alpha-1(IV) chain
CLIA Kit for Mouse Collagen alpha-1(IV) chain
CLIA Kit for Mouse Collagen alpha-1(IV) chain
CLIA Kit for Mouse Collagen alpha-1(IV) chain
Polyclonal Antibody for Mouse Collagen alpha-1(IV) chain
Polyclonal Antibody for Mouse Collagen alpha-1(IV) chain
Polyclonal Antibody for Mouse Collagen alpha-1(IV) chain
Polyclonal Antibody for Mouse Collagen alpha-1(IV) chain
Monoclonal Antibody for Mouse Collagen alpha-1(IV) chain
Monoclonal Antibody for Mouse Collagen alpha-1(IV) chain
Monoclonal Antibody for Mouse Collagen alpha-1(IV) chain
Monoclonal Antibody for Mouse Collagen alpha-1(IV) chain
Protein for Mouse Collagen alpha-1(IV) chain
Protein for Mouse Collagen alpha-1(IV) chain
Protein for Mouse Collagen alpha-1(IV) chain
Protein for Mouse Collagen alpha-1(IV) chain
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
"The transcriptional landscape of the mammalian genome."
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6 .
strain :
C57BL/6J .
tissue :
Brain .
tissue :
Eye .
tissue :
Heart .
tissue :
Placenta .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6 .
strain :
FVB/N .
tissue :
Brain .
tissue :
Colon .
tissue :
Mammary gland .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-1154
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-129
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1110-1135
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1149-1424
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1276-1669
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1441-1669
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE