COL6A3 ELISA Kit for Human(Homo sapiens) | EIAab.comCOL6A3 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > COL6A3(Gene name) > Human

COL6A3 (Gene name),

Collagen alpha-3(VI) chain (Protein name ), CO6A3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

COL6A3;

Protein name:

Collagen alpha-3(VI) chain;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Trimers composed of three different chains: alpha-1(VI), alpha-2(VI), and alpha-3(VI) or alpha-5(VI) or alpha-6(VI).

Function:

Collagen VI acts as a cell-binding protein.

Subcellular Location:

Secreted extracellular space extracellular matrix

Protein Attributes:

Sequence length:

3177

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3177:

KFGSQKECEK | VCAPVLAKPG | VISVMGT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF01391

String:

P12111

UniGene:

Hs.233240

KEGG:

hsa:1293

STRING:

9606.ENSP00000295550

MIM:

120250

SMR:

P12111

Uniprot:

P12111

FOR

ELISA Kit for Human Collagen alpha-3(VI) chain

CLIA Kit for Human Collagen alpha-3(VI) chain

Polyclonal Antibody for Human Collagen alpha-3(VI) chain

Monoclonal Antibody for Human Collagen alpha-3(VI) chain

Protein for Human Collagen alpha-3(VI) chain

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Mosaic structure of globular domains in the human type VI collagen alpha 3 chain: similarity to von Willebrand factor, fibronectin, actin, salivary proteins and aprotinin type protease inhibitors."
Chu M.-L. , Zhang R.-Z. , Pan T.-C. , Stokes D. , Conway D. , Kuo H.-J. , Glanville R. , Mayer U. , Mann K. , Deutzmann R. , Timpl R.
EMBO J.9:385-393(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;HYDROXYLATION;VARIANTS VAL-2431; THR-2927; VAL-2988 AND PRO-3012
tissue: Fibroblast.
2.

Chu M.-L.
Submitted (1998-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
3.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 5)
tissue: Uterus.
4.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
6.

"The human type VI collagen gene. mRNA and protein variants of the alpha 3 chain generated by alternative splicing of an additional 5-end exon."
Zanussi S. , Doliana R. , Segat D. , Bonaldo P. , Colombatti A.
J. Biol. Chem.267:24082-24089(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 32-236;ALTERNATIVE SPLICING
7.

"Amino acid sequence of the triple-helical domain of human collagen type VI."
Chu M.-L. , Conway D. , Pan T.-C. , Baldwin C. , Mann K. , Deutzmann R. , Timpl R.
J. Biol. Chem.263:18601-18606(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2038-2373
8.

"Characterization of three constituent chains of collagen type VI by peptide sequences and cDNA clones."
Chu M.-L. , Mann K. , Deutzmann R. , Pribula-Conway D. , Hsu-Chen C.-C. , Bernard M.P. , Timpl R.
Eur. J. Biochem.168:309-317(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2092-2157
9.

"Cloning and chromosomal localization of human genes encoding the three chains of type VI collagen."
Weil D. , Mattei M.-G. , Passage E. , N'Guyen V.C. , Pribula-Conway D. , Mann K. , Deutzmann R. , Timpl R. , Chu M.-L.
Am. J. Hum. Genet.42:435-445(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2092-2151
tissue: Placenta.
10.

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-2677
tissue: Plasma.
11.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-2079 AND ASN-2677
tissue: Liver.
12.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-433;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"The 1.6 A structure of Kunitz-type domain from the alpha 3 chain of human type VI collagen."
Arnoux B. , Merigeau K. , Saludjian P. , Norris F. , Norris K. , Bjoern S. , Olsen O. , Petersen L. , Ducruix A.
J. Mol. Biol.246:609-617(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS) OF 3108-3165
14.

"Structure and multiple conformations of the Kunitz-type domain from human type VI collagen alpha3(VI) chain in solution."
Zweckstetter M. , Czisch M. , Mayer U. , Chu M.-L. , Zinth W. , Timpl R. , Holak T.A.
Structure4:195-209(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 3103-3165
15.

"Solution structure and backbone dynamics of the human alpha3-chain type VI collagen C-terminal Kunitz domain."
Soerensen M.D. , Bjoern S. , Norris K. , Olsen O. , Petersen L. , James T.L. , Led J.J.
Biochemistry36:10439-10450(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 3108-3165
16.

"Mutations in COL6A3 cause severe and mild phenotypes of Ullrich congenital muscular dystrophy."
Demir E. , Sabatelli P. , Allamand V. , Ferreiro A. , Moghadaszadeh B. , Makrelouf M. , Topaloglu H. , Echenne B. , Merlini L. , Guicheney P.
Am. J. Hum. Genet.70:1446-1458(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISEASE
17.

"Missense mutation in a von Willebrand factor type A domain of the alpha 3(VI) collagen gene (COL6A3) in a family with Bethlem myopathy."
Pan T.-C. , Zhang R.-Z. , Pericak-Vance M.A. , Tandan R. , Fries T. , Stajich J.M. , Viles K. , Vance J.M. , Chu M.-L. , Speer M.C.
Hum. Mol. Genet.7:807-812(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BM GLU-1679;VARIANT HIS-2831
18.

"A novel de novo mutation in the triple helix of the COL6A3 gene in a two-generation Italian family affected by Bethlem myopathy. A diagnostic approach in the mutations' screening of type VI collagen."
Pepe G. , Bertini E. , Giusti B. , Brunelli T. , Comeglio P. , Saitta B. , Merlini L. , Chu M.L. , Federici G. , Abbate R.
Neuromuscul. Disord.9:264-271(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BM ARG-2056
19.

"Automated genomic sequence analysis of the three collagen VI genes: applications to Ullrich congenital muscular dystrophy and Bethlem myopathy."
Lampe A.K. , Dunn D.M. , von Niederhausern A.C. , Hamil C. , Aoyagi A. , Laval S.H. , Marie S.K. , Chu M.-L. , Swoboda K. , Muntoni F. , Bonnemann C.G. , Flanigan K.M. , Bushby K.M.D. , Weiss R.B.
J. Med. Genet.42:108-120(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS BM HIS-677; GLU-1014; LYS-1386; ASP-1467; GLU-1679; MET-1985; ASP-2047; ASP-2080 AND VAL-2941;VARIANTS UCMD GLN-1064; GLN-1395 AND ASN-1674;VARIANTS VAL-411; HIS-491; SER-492; THR-807; SER-830; GLN-1088; GLN-1576; GLN-1632; SER-1687; LEU-2218 AND HIS-2831
20.

"Molecular consequences of dominant Bethlem myopathy collagen VI mutations."
Baker N.L. , Moergelin M. , Pace R.A. , Peat R.A. , Adams N.E. , Gardner R.J. , Rowland L.P. , Miller G. , De Jonghe P. , Ceulemans B. , Hannibal M.C. , Edwards M. , Thompson E.M. , Jacobson R. , Quinlivan R.C.M. , Aftimos S. , Kornberg A.J. , North K.N. , more...
Ann. Neurol.62:390-405(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BM ARG-1726;VARIANTS HIS-677; GLN-1576; VAL-2431; LYS-2453; HIS-2831; VAL-2988 AND ILE-3069

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