Protein name:
Collagen alpha-1(VIII) chain ;
Alternative:
Organism:
Chicken (Gallus gallus).
General Annotation
Sub Unit:
Homotrimers, or heterotrimers in association with alpha 2(VIII) type collagens. Four homotrimers can form a tetrhedron stabilized by central interacting C-terminal NC1 trimers.
Function:
Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in artherogenesis.
Subcellular Location:
Secreted
extracellular space
extracellular matrix
basement membrane
Protein Attributes:
50:
MAVQPGPPQL | LQVLLTISLG | SIRLIQAGAY | YGIKPLPPQI | PPQMPPQIPQ |
100:
YQPLGQQVPH | MPLAKDGLTM | GKEMPHAQYG | KEYPHLPQYM | KEVQPVPRMG |
150:
KEAVPKKGKE | IPLASLRGEQ | GPRGEPGPRG | PPGPPGLPGQ | GIPGIKGKPG |
200:
PQGYPGVGKP | GMPGMPGKPG | AMGMPGAKGE | IGPKGEIGPM | GIPGPQGPPG |
250:
PHGLPGIGKP | GGPGLPGQPG | AKGDRGPKGP | PGPPGLQGPK | GEKGFGMPGL |
300:
PGLKGPPGMH | GPPGPVGLPG | VGKPGVTGFP | GPQGPLGKPG | PPGEPGPQGP |
350:
IGVPGVQGPP | GLPGVGKPGQ | DGIPGQPGFP | GGKGEQGLPG | LPGPPGLPGV |
400:
GKPGFPGPKG | DRGIGGVPGA | LGPRGEKGPV | GAPGMGGPPG | EPGLPGIPGP |
450:
MGPPGAIGFP | GPKGEGGIVG | PQGPPGPKGE | PGLQGFPGKP | GFLGEVGPPG |
500:
IRGLPGPIGP | KGEAGHKGLP | GLPGVPGLLG | PKGEPGIPGD | QGLQGPPGIP |
550:
GITGPSGPIG | PPGIPGPKGE | PGLPGPPGFP | GVGKPGVAGL | HGPPGKPGAL |
600:
GPQGQPGLPG | PPGPPGPPGP | PAVMPPTPAP | QGEYLPDMGL | GIDGVKTPHA |
650:
YAAKKGKNGG | PAYEMPAFTA | ELTAPFPPVG | APIKFDRLLY | NGRQNYNPQT |
700:
GIFTCEVPGV | YYFAYHVHCK | GGNVWVALFK | NNEPVMYTYD | EYKKGFLDQA |
744:
SGSAVLLLRP | GDRVFLQNPS | EQAAGLYAGQ | YVHSSFSGYL | LYPM
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Chicken
Human
Rabbit
Mouse
ELISA Kit for Chicken Collagen alpha-1(VIII) chain
ELISA Kit for Chicken Collagen alpha-1(VIII) chain
ELISA Kit for Chicken Collagen alpha-1(VIII) chain
ELISA Kit for Chicken Collagen alpha-1(VIII) chain
CLIA Kit for Chicken Collagen alpha-1(VIII) chain
CLIA Kit for Chicken Collagen alpha-1(VIII) chain
CLIA Kit for Chicken Collagen alpha-1(VIII) chain
CLIA Kit for Chicken Collagen alpha-1(VIII) chain
Polyclonal Antibody for Chicken Collagen alpha-1(VIII) chain
Polyclonal Antibody for Chicken Collagen alpha-1(VIII) chain
Polyclonal Antibody for Chicken Collagen alpha-1(VIII) chain
Polyclonal Antibody for Chicken Collagen alpha-1(VIII) chain
Monoclonal Antibody for Chicken Collagen alpha-1(VIII) chain
Monoclonal Antibody for Chicken Collagen alpha-1(VIII) chain
Monoclonal Antibody for Chicken Collagen alpha-1(VIII) chain
Monoclonal Antibody for Chicken Collagen alpha-1(VIII) chain
Protein for Chicken Collagen alpha-1(VIII) chain
Protein for Chicken Collagen alpha-1(VIII) chain
Protein for Chicken Collagen alpha-1(VIII) chain
Protein for Chicken Collagen alpha-1(VIII) chain
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"The molecular biology of collagens with short triple-helical domains."
Ninomiya Y.
,
Castagnola P.
,
Gerecke D.
,
Gordon M.K.
,
Jacenko O.
,
LuValle P.
,
McCarthy M.
,
Muragaki Y.
,
Nishimura I.
,
Oh S.
,
Rosenblum N.
,
Sato N.
,
Sugrue S.
,
Taylor R.
,
Vasios G.
,
Yamaguchi N.
,
Olsen B.R.
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Cited for : NUCLEOTIDE SEQUENCE