COL10A1 ELISA Kit for Human(Homo sapiens) | EIAab.comCOL10A1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > COL10A1(Gene name) > Human

COL10A1 (Gene name),

Collagen alpha-1(X) chain (Protein name ), COAA1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

COL10A1;

Protein name:

Collagen alpha-1(X) chain;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homotrimer.

Function:

Type X collagen is a product of hyperthrophic chondrotocytes and has been localized to presumptive mineralization zones of hyaline cartilage.

Subcellular Location:

Secreted extracellular space extracellular matrix

Protein Attributes:

Sequence length:

680

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

680:

WLQLPNAESN | GLYSSEYVHS | SFSGFLVAPM |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000243222

MIM:

120110

Pfam:

PF00386

SMR:

Q03692

KEGG:

hsa:1300

UniGene:

Hs.520339

String:

Q03692

Uniprot:

Q03692

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ELISA Kit for Human Collagen alpha-1(X) chain

Cat.:

E1467h

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96T

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ELISA Kit for Human Collagen alpha-1(X) chain

Cat.:

E1467m

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96T

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ELISA Kit for Human Collagen alpha-1(X) chain

Cat.:

E1467c

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Packing:

96T

ELISA Kit for Human Collagen alpha-1(X) chain

Cat.:

E1467b

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Packing:

96T

CLIA Kit for Human Collagen alpha-1(X) chain

Cat.:

U1467b

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Packing:

96T

CLIA Kit for Human Collagen alpha-1(X) chain

Cat.:

U1467c

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Packing:

96T

CLIA Kit for Human Collagen alpha-1(X) chain

Cat.:

U1467m

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MSDS:

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Packing:

96T

CLIA Kit for Human Collagen alpha-1(X) chain

Cat.:

U1467h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Collagen alpha-1(X) chain

Cat.:

P1467Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Collagen alpha-1(X) chain

Cat.:

P1467Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Collagen alpha-1(X) chain

Monoclonal Antibody for Human Collagen alpha-1(X) chain

Protein for Human Collagen alpha-1(X) chain

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"The human collagen X gene. Complete primary translated sequence and chromosomal localization."
Thomas J.T. , Cresswell C.J. , Rash B. , Nicolai H. , Jones T. , Solomon E. , Grant M.E. , Boot-Handford R.P.
Biochem. J.280:617-623(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT THR-27
2.

"Genomic organization and full-length cDNA sequence of human collagen X."
Reichenberger E. , Beier F. , LuValle P. , Olsen B.R. , von der Mark K. , Bertling W.M.
FEBS Lett.311:305-310(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

Beier F. , Lammi M.B. , von der Mark K.
Submitted (1996-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"The DNA sequence and analysis of human chromosome 6."
Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
7.

"Cloning of the human and mouse type X collagen genes and mapping of the mouse type X collagen gene to chromosome 10."
Apte S.S. , Seldin M.F. , Hayashi M. , Olsen B.R.
Eur. J. Biochem.206:217-224(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 52-680
8.

"Cloning of human alpha 1(X) collagen DNA and localization of the COL10A1 gene to the q21-q22 region of human chromosome 6."
Apte S. , Mattei M.-G. , Olsen B.R.
FEBS Lett.282:393-396(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 561-666
9.

"In situ hybridization studies on the expression of type X collagen in fetal human cartilage."
Reichenberger E. , Aigner T. , von der Mark K. , Stoeb H. , Bertling W.
Dev. Biol.148:562-572(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 547-655
10.

"Insight into Schmid metaphyseal chondrodysplasia from the crystal structure of the collagen X NC1 domain trimer."
Bogin O. , Kvansakul M. , Rom E. , Singer J. , Yayon A. , Hohenester E.
Structure10:165-173(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 521-680;CALCIUM-BINDING
11.

"Mutations in fibrillar collagens (types I, II, III, and XI), fibril-associated collagen (type IX), and network-forming collagen (type X) cause a spectrum of diseases of bone, cartilage, and blood vessels."
Kuivaniemi H. , Tromp G. , Prockop D.J.
Hum. Mutat.9:300-315(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON VARIANTS
12.

"Amino acid substitutions of conserved residues in the carboxyl-terminal domain of the alpha 1(X) chain of type X collagen occur in two unrelated families with metaphyseal chondrodysplasia type Schmid."
Wallis G.A. , Rash B. , Sweetman W.A. , Thomas J.T. , Super M. , Evans G. , Grant M.E. , Boot-Handford R.P.
Am. J. Hum. Genet.54:169-178(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SMCD ASP-598 AND PRO-614
13.

"Additional mutations of type X collagen confirm COL10A1 as the Schmid metaphyseal chondrodysplasia locus."
McIntosh I. , Abbott M.H. , Warman M.L. , Olsen B.R. , Francomano C.A.
Hum. Mol. Genet.3:303-307(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SMCD ARG-591
14.

"Type X collagen multimer assembly in vitro is prevented by a Gly618 to Val mutation in the alpha 1(X) NC1 domain resulting in Schmid metaphyseal chondrodysplasia."
Chan D. , Cole W.G. , Rogers J.G. , Bateman J.F.
J. Biol. Chem.270:4558-4562(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SMCD VAL-618
15.

"Mutations in three subdomains of the carboxy-terminal region of collagen type X account for most of the Schmid metaphyseal dysplasias."
Bonaventure J. , Chaminade F. , Maroteaux P.
Hum. Genet.96:58-64(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SMCD ARG-545; GLU-595; HIS-597; LYS-617; ARG-644 AND GLY-648
16.

"Mutations within the gene encoding the alpha 1 (X) chain of type X collagen (COL10A1) cause metaphyseal chondrodysplasia type Schmid but not several other forms of metaphyseal chondrodysplasia."
Wallis G.A. , Rash B. , Sykes B. , Bonaventure J. , Maroteaux P. , Zabel B. , Wynne-Davies R. , Grant M.E. , Boot-Handford R.P.
J. Med. Genet.33:450-457(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SMCD PRO-600
17.

"Mutations in the N-terminal globular domain of the type X collagen gene (COL10A1) in patients with schmid metaphyseal chondrodysplasia."
Ikegawa S. , Nakamura K. , Nagano A. , Haga N. , Nakamura Y.
Hum. Mutat.9:131-135(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SMCD GLU-18 AND ARG-18
18.

"Mutation of the type X collagen gene 'COL10A1' causes spondylometaphyseal dysplasia."
Ikegawa S. , Nishimura G. , Nagai T. , Hasegawa T. , Ohashi H. , Nakamura Y.
Am. J. Hum. Genet.63:1659-1662(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SPONDYLOMETAPHYSEAL DYSPLASIA JAPANESE TYPE GLU-595
19.

"Novel missense mutation resulting in the substitution of tyrosine by cysteine at codon 597 of the type X collagen gene associated with Schmid metaphyseal chondrodysplasia."
Sawai H. , Ida A. , Nakata Y. , Koyama K.
J. Hum. Genet.43:259-261(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SMCD CYS-597
20.

"Mutations of COL10A1 in Schmid metaphyseal chondrodysplasia."
Bateman J.F. , Wilson R. , Freddi S. , Lamande S.R. , Savarirayan R.
Hum. Mutat.25:525-534(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SMCD ARG-18; GLU-18; ASP-582; ARG-591; ARG-595; GLU-595; HIS-597; CYS-597; ASP-598; PRO-600; PRO-614; LYS-617; VAL-618; ARG-644; GLY-648; ARG-651; PRO-653 AND PRO-671;VARIANTS THR-27; HIS-198; ARG-545 AND MET-603

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