Gene name:
COPR5 (C17orf79) ;
Protein name:
Cooperator of PRMT5 ;
Alternative:
Protein TTP1 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with PRMT5. Interacts with histone H4; specifically interacts with the N-terminus of histone H4 but not with histone H3.
Function:
Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MDLQAAGAQA | QGAAEPSRGP | PLPSARGAPP | SPEAGFATAD | HSSQERETEK |
100:
AMDRLARGTQ | SIPNDSPARG | EGTHSEEEGF | AMDEEDSDGE | LNTWELSEGT |
150:
NCPPKEQPGD | LFNEDWDSEL | KADQGNPYDA | DDIQESISQE | LKPWVCCAPQ |
184:
GDMIYDPSWH | HPPPLIPYYS | KMVFETGQFD | DAED
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Bovine
ELISA Kit for Human Cooperator of PRMT5
ELISA Kit for Human Cooperator of PRMT5
ELISA Kit for Human Cooperator of PRMT5
CLIA Kit for Human Cooperator of PRMT5
CLIA Kit for Human Cooperator of PRMT5
CLIA Kit for Human Cooperator of PRMT5
Polyclonal Antibody for Human Cooperator of PRMT5
Polyclonal Antibody for Human Cooperator of PRMT5
Polyclonal Antibody for Human Cooperator of PRMT5
Monoclonal Antibody for Human Cooperator of PRMT5
Monoclonal Antibody for Human Cooperator of PRMT5
Monoclonal Antibody for Human Cooperator of PRMT5
Protein for Human Cooperator of PRMT5
Protein for Human Cooperator of PRMT5
Protein for Human Cooperator of PRMT5
R&D Technical Data
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Precision
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Recovery
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Linearity
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