MT-CO1 ELISA Kit for Human(Homo sapiens) | EIAab.comMT-CO1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > MT-CO1(Gene name) > Human

MT-CO1 (Gene name),

Cytochrome c oxidase subunit 1 (Protein name ), COX1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MT-CO1(COI;COXI;MTCO1);

Protein name:

Cytochrome c oxidase subunit 1;

Alternative:

Cytochrome c oxidase polypeptide I;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.

Subcellular Location:

Mitochondrion inner membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

513

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

513:

PYHTFEEPVY | MKS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P00395

Pfam:

PF00115

SMR:

P00395

MIM:

114500

KEGG:

hsa:4512

Uniprot:

P00395

FOR

ELISA Kit for Human Cytochrome c oxidase subunit 1

Cat.:

E8727h

Price:

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Manual:

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Packing:

96T

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ELISA Kit for Human Cytochrome c oxidase subunit 1

MSDS:

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ELISA Kit for Human Cytochrome c oxidase subunit 1

MSDS:

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ELISA Kit for Human Cytochrome c oxidase subunit 1

Cat.:

E8727b

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Packing:

96T

ELISA Kit for Human Cytochrome c oxidase subunit 1

Cat.:

E8727p

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MSDS:

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Packing:

96T

ELISA Kit for Human Cytochrome c oxidase subunit 1

MSDS:

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CLIA Kit for Human Cytochrome c oxidase subunit 1

Cat.:

U8727b

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MSDS:

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Packing:

96T

CLIA Kit for Human Cytochrome c oxidase subunit 1

MSDS:

Please sign in first.

CLIA Kit for Human Cytochrome c oxidase subunit 1

MSDS:

Please sign in first.

CLIA Kit for Human Cytochrome c oxidase subunit 1

MSDS:

Please sign in first.

CLIA Kit for Human Cytochrome c oxidase subunit 1

Cat.:

U8727h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

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CLIA Kit for Human Cytochrome c oxidase subunit 1

Cat.:

U8727p

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Cytochrome c oxidase subunit 1

Cat.:

P8727Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Cytochrome c oxidase subunit 1

Monoclonal Antibody for Human Cytochrome c oxidase subunit 1

Protein for Human Cytochrome c oxidase subunit 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Sequence and organization of the human mitochondrial genome."
Anderson S. , Bankier A.T. , Barrell B.G. , de Bruijn M.H.L. , Coulson A.R. , Drouin J. , Eperon I.C. , Nierlich D.P. , Roe B.A. , Sanger F. , Schreier P.H. , Smith A.J.H. , Staden R. , Young I.G.
Nature290:457-465(1981) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
2.

"Recent African origin of modern humans revealed by complete sequences of hominoid mitochondrial DNAs."
Horai S. , Hayasaka K. , Kondo R. , Tsugane K. , Takahata N.
Proc. Natl. Acad. Sci. U.S.A.92:532-536(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS SER-235 AND ALA-415
tissue: Placenta.
3.

"Lineage-specific selection in human mtDNA: lack of polymorphisms in a segment of MTND5 gene in haplogroup J."
Moilanen J.S. , Finnila S. , Majamaa K.
Mol. Biol. Evol.20:2132-2142(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Mitochondrial genome variation and the origin of modern humans."
Ingman M. , Kaessmann H. , Paeaebo S. , Gyllensten U.
Nature408:708-713(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

"Mitochondrial genome variation and evolutionary history of Australian and New Guinean aborigines."
Ingman M. , Gyllensten U.
Genome Res.13:1600-1606(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"Single nucleotide polymorphisms over the entire mtDNA genome that increase the power of forensic testing in Caucasians."
Coble M.D. , Just R.S. , O'Callaghan J.E. , Letmanyi I.H. , Peterson C.T. , Irwin J.A. , Parsons T.J.
Int. J. Legal Med.118:137-146(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.

"Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing."
Sanger F. , Coulson A.R. , Barrell B.G. , Smith A.J.H. , Roe B.A.
J. Mol. Biol.143:161-178(1980) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-187
8.

"Heterogenous point mutations in the mitochondrial tRNA Ser(UCN) precursor coexisting with the A1555G mutation in deaf students from Mongolia."
Pandya A. , Xia X.J. , Erdenetungalag R. , Amendola M. , Landa B. , Radnaabazar J. , Dangaasuren B. , Van Tuyle G. , Nance W.E.
Am. J. Hum. Genet.65:1803-1806(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN DFNM
9.

"Normal variants of human mitochondrial DNA and translation products: the building of a reference data base."
Marzuki S. , Noer A.S. , Lertrit P. , Thyagarajan D. , Kapsa R. , Utthanaphol P. , Byrne E.
Hum. Genet.88:139-145(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ALA-10; CYS-94; LEU-155; ALA-224 AND LEU-305
10.

"A mitochondrial DNA variant, identified in Leber hereditary optic neuropathy patients, which extends the amino acid sequence of cytochrome c oxidase subunit I."
Brown M.D. , Yang C.-C. , Trounce I. , Torroni A. , Lott M.T. , Wallace D.C.
Am. J. Hum. Genet.51:378-385(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LHON LYS-GLN-LYS-513 INS
11.

"Heteroplasmic point mutations of mitochondrial DNA affecting subunit I of cytochrome c oxidase in two patients with acquired idiopathic sideroblastic anemia."
Gattermann N. , Retzlaff S. , Wang Y.L. , Hofhaus G. , Heinisch J. , Aul C. , Schneider W.
Blood90:4961-4972(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS THR-273 AND THR-280;POSSIBLE INVOLVEMENT IN ACQUIRED IDIOPATHIC SIDEROBLASTIC ANEMIA
12.

"MtDNA mutations associated with sideroblastic anaemia cause a defect of mitochondrial cytochrome c oxidase."
Broker S. , Meunier B. , Rich P. , Gattermann N. , Hofhaus G.
Eur. J. Biochem.258:132-138(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS THR-273 AND THR-280;POSSIBLE INVOLVEMENT IN ACQUIRED IDIOPATHIC SIDEROBLASTIC ANEMIA
13.

"Recurrent myoglobinuria due to a nonsense mutation in the COX I gene of mitochondrial DNA."
Karadimas C.L. , Greenstein P. , Sue C.M. , Joseph J.T. , Tanji K. , Haller R.G. , Taivassalo T. , Davidson M.M. , Shanske S. , Bonilla E. , DiMauro S.
Neurology55:644-649(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN RM-MT
14.

"Metabolic consequences of a novel missense mutation of the mtDNA CO I gene."
Varlamov D.A. , Kudin A.P. , Vielhaber S. , Schroeder R. , Sassen R. , Becker A. , Kunz D. , Haug K. , Rebstock J. , Heils A. , Elger C.E. , Kunz W.S.
Hum. Mol. Genet.11:1797-1805(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MT-C4D ILE-196
15.

"Introducing a novel human mtDNA mutation into the Paracoccus denitrificans COX I gene explains functional deficits in a patient."
Lucioli S. , Hoffmeier K. , Carrozzo R. , Tessa A. , Ludwig B. , Santorelli F.M.
Neurogenetics7:51-57(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MT-C4D PHE-142;CHARACTERIZATION OF VARIANT MT-C4D PHE-142
16.

"Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission."
Greaves L.C. , Preston S.L. , Tadrous P.J. , Taylor R.W. , Barron M.J. , Oukrif D. , Leedham S.J. , Deheragoda M. , Sasieni P. , Novelli M.R. , Jankowski J.A.Z. , Turnbull D.M. , Wright N.A. , McDonald S.A.C.
Proc. Natl. Acad. Sci. U.S.A.103:714-719(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CRC ASP-125 AND PRO-458
17.

"A mitochondrial DNA mutation linked to colon cancer results in proton leaks in cytochrome c oxidase."
Namslauer I. , Brzezinski P.
Proc. Natl. Acad. Sci. U.S.A.106:3402-3407(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANTS CRC ASP-125 AND PRO-458

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