Gene name:
CEP135 (CEP4;KIAA0635) ;
Protein name:
Centrosomal protein of 135 kDa (Cep135) ;
Alternative:
Centrosomal protein 4 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with DCTN2 (By similarity). Interacts with CEP250.
Function:
Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole.
Subcellular Location:
Cytoplasm
cytoskeleton
centrosome
centriole
During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles.
Protein Attributes:
50:
MTTAVERKYI | NIRKRLDQLG | YRQTLTVECL | PLVEKLFSDL | VHTTESLRQS |
100:
KLSAVKAEKE | SANFDFVLEP | YKLENARLSR | ENNELYLELM | KLREHSDQHV |
150:
KELKTSLKKC | ARETADLKFL | NNQYAHKLKL | LEKESKAKNE | RIQQLQEKNL |
200:
HAVVQTPGGK | KRSIAFRRQR | MQIDEPVPPS | EVSSYPVPQP | DDPYIADLLQ |
250:
VADNRIQELQ | QEVHQLQEKL | AMMESGVRDY | SKQIELRERE | IERLSVALDG |
300:
GRSPDVLSLE | SRNKTNEKLI | AHLNIQVDFL | QQANKDLEKR | IRELMETKET |
350:
VTSEVVNLSN | KNEKLCQELT | EIDQLAQQLE | RHKEEVLETA | DKELGEAKKE |
400:
IKRKLSEMQD | LEETMAKLQL | ELNLCQKEKE | RLSDELLVKS | DLETVVHQLE |
450:
QEKQRLSKKV | ESFAVTERQL | TLEVERMRLE | HGIKRRDRSP | SRLDTFLKGI |
500:
EEERDYYKKE | LERLQHIIQR | RSCSTSYSAR | EKSSIFRTPE | KGDYNSEIHQ |
550:
ITRERDELQR | MLERFEKYME | DIQSNVKLLT | AERDKLSVLY | NEAQEELSAL |
600:
RKESTQTTAP | HNIVSLMEKE | KELALSDLRR | IMAEKEALRE | KLEHIEEVSL |
650:
FGKSELEKTI | EHLTCVNHQL | ESEKYELKSK | VLIMKETIES | LENKLKVQAQ |
700:
KFSHVAGDSS | HQKTEVNSLR | IVNEQLQRSV | DDYQHRLSIK | RGELESAQAQ |
750:
IKILEEKIDE | LNLKMTSQDE | EAHVMKKTIG | VIDKEKDFLQ | ETVDEKTEKI |
800:
ANLQENLANK | EKAVAQMKIM | ISECESSVNQ | LKETLVNRDR | EINSLRRQLD |
850:
AAHKELDEVG | RSREIAFKEN | RRLQDDLATM | ARENQEISLE | LEAAVQEKEE |
900:
MKSRVHKYIT | EVSRWESLMA | AKEKENQDLL | DRFQMLHNRA | EDWEVKAHQA |
950:
EGESSSVRLE | LLSIDTERRH | LRERVELLEK | EIQEHINAHH | AYESQISSMA |
1000:
KAMSRLEEEL | RHQEDEKATV | LNDLSSLREL | CIKLDSGKDI | MTQQLNSKNL |
1050:
EFERVVVELE | NVKSESDLLK | KQLSNERHTV | KNLESLLATN | RDKEFHSHLT |
1100:
SHEKDTEIQL | LKEKLTLSES | KLTSQSRENT | MLRAKVAQLQ | TDYDALKRQI |
1140:
STERYERERA | IQEMRRHGLA | TPPLSSTLRS | PSHSPEHRNV |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Cep135
ELISA Kit for Human Cep135
CLIA Kit for Human Cep135
CLIA Kit for Human Cep135
Polyclonal Antibody for Human Cep135
Polyclonal Antibody for Human Cep135
Monoclonal Antibody for Human Cep135
Monoclonal Antibody for Human Cep135
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Placenta .
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Testis .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 277-1140 (ISOFORM 1)
tissue :
Brain .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION (ISOFORM 1);SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
tissue :
Lymphoblast .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH CEP250
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INVOLVEMENT IN MCPH8