Cyp2a4 ELISA Kit for Mouse(Mus musculus) | EIAab.comCyp2a4 ELISA Kit for Mouse(Mus musculus)

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Cyp2a4 (Gene name),

Cytochrome P450 2A4 (Protein name ), CP2A4_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cyp2a4(Cyp2a-4);

Protein name:

Cytochrome P450 2A4;

Alternative:

Cytochrome P450-15-alpha;CYPIIA4;Testosterone 15-alpha-hydroxylase;Cytochrome P450-IIA3.1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Highly active in the 15-alpha-hydroxylation of testosterone. Also active in the 15-alpha-hydroxylation of progesterone and androstenedione. Little or no activity on corticosterone, pregnenolone, dehydroepiandrosterone, estradiol or estriol.

Subcellular Location:

Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein

Protein Attributes:

Sequence length:

494

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

494:

LFLTNIMQNF | HFKSTQAPQD | IDVSPRLVGF | VTIPPTYTMS | FLSR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P15392

String:

P15392

Pfam:

PF00067

KEGG:

mmu:13086

STRING:

10090.ENSMUSP00000096254

UniGene:

Mm.154643

Uniprot:

P15392

FOR

ELISA Kit for Mouse Cytochrome P450 2A4

CLIA Kit for Mouse Cytochrome P450 2A4

Polyclonal Antibody for Mouse Cytochrome P450 2A4

Monoclonal Antibody for Mouse Cytochrome P450 2A4

Protein for Mouse Cytochrome P450 2A4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The structure and characterization of type I P-450(15) alpha gene as major steroid 15 alpha-hydroxylase and its comparison with type II P-450(15) alpha gene."
Lindberg R. , Burkhart B. , Ichikawa T. , Negishi M.
J. Biol. Chem.264:6465-6471(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Liver.
2.

"Reciprocal regulation of sex-dependent expression of testosterone 15 alpha-hydroxylase (P-450(15 alpha)) in liver and kidney of male mice by androgen. Evidence for a single gene."
Squires E.J. , Negishi M.
J. Biol. Chem.263:4166-4171(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Kidney.
5.

"Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue."
Lindberg R. , Negishi M.
Nature339:632-634(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS
6.

"Circadian expression of the steroid 15 alpha-hydroxylase (Cyp2a4) and coumarin 7-hydroxylase (Cyp2a5) genes in mouse liver is regulated by the PAR leucine zipper transcription factor DBP."
Lavery D.J. , Lopez-Molina L. , Margueron R. , Fleury-Olela F. , Conquet F. , Schibler U. , Bonfils C.
Mol. Cell. Biol.19:6488-6499(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY

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