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Index > Protein center > Cyp2b2(Gene name) > Rat
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  • Cyp2b2 (Gene name),
  • Cytochrome P450 2B2 (Protein name ),  CP2B2_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Cyp2b2(Cyp2b-2);
    Protein name:
    Cytochrome P450 2B2;
    Alternative:
    Cytochrome P450 PB4;CYPIIB2;Cytochrome P450E;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
    Subcellular Location:
    Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    491
    Sequence:
    50:
    MEPSILLLLA | LLVGFLLLLV | RGHPKSRGNF | PPGPRPLPLL | GNLLQLDRGG | 
    100:
    LLNSFMQLRE | KYGDVFTVHL | GPRPVVMLCG | TDTIKEALVG | QAEDFSGRGT | 
    150:
    IAVIEPIFKE | YGVIFANGER | WKALRRFSLA | TMRDFGMGKR | SVEERIQEEA | 
    200:
    QCLVEELRKS | QGAPLDPTFL | FQCITANIIC | SIVFGERFDY | TDRQFLRLLE | 
    250:
    LFYRTFSLLS | SFSSQVFEFF | SGFLKYFPGA | HRQISKNLQE | ILDYIGHIVE | 
    300:
    KHRATLDPSA | PRDFIDTYLL | RMEKEKSNHH | TEFHHENLMI | SLLSLFFAGT | 
    350:
    ETGSTTLRYG | FLLMLKYPHV | TEKVQKEIDQ | VIGSHRPPSL | DDRTKMPYTD | 
    400:
    AVIHEIQRFA | DLAPIGLPHR | VTKDTMFRGY | LLPKNTEVYP | ILSSALHDPQ | 
    450:
    YFDHPDTFNP | EHFLDADGTL | KKSEAFMPFS | TGKRICLGEG | IARNELFLFF | 
    491:
    TTILQNFSVS | SHLAPKDIDL | TPKESGIAKI | PPTYQICFSA | R
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    String:
    UniGene:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Cytochrome P450 2B2
    Cat.:
    E15012r
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Cytochrome P450 2B2
    Cat.:
    U15012r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Cytochrome P450 2B2
    Cat.:
    P15012Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Cytochrome P450 2B2
    Protein for Rat Cytochrome P450 2B2

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
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    Recovery
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Gene structure of a phenobarbital-inducible cytochrome P-450 in rat liver."
      Mizukami Y. , Sogawa K. , Suwa Y. , Muramatsu M. , Fujii-Kuriyama Y.
      Proc. Natl. Acad. Sci. U.S.A.80:3958-3962(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
    2. 2.
      "The structure of phenobarbital-inducible rat liver cytochrome P-450 isoenzyme PB-4. Production and characterization of site-specific antibodies."
      Frey A.B. , Waxman D.J. , Kreibich G.
      J. Biol. Chem.260:15253-15265(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE (ISOFORM 1)
    3. 3.
      "Alternative splicing of mRNA encoding rat liver cytochrome P450e (P450IIB2)."
      Lacroix D. , Desrochers M. , Lambert M. , Anderson A.
      Gene86:201-207(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 105-491 (ISOFORM 2)
    4. 4.
      "Cloning and sequence analysis of a rat liver cDNA coding for a phenobarbital-inducible microheterogenous cytochrome P-450 variant: regulation of its messenger level by xenobiotics."
      Phillips I.R. , Shephard E.A. , Ashworth A. , Rabin B.R.
      Gene26:41-52(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 168-491 (ISOFORM 1)
    5. 5.
      "Cloned cytochrome P-450 cDNA. Nucleotide sequence and homology to multiple phenobarbital-induced mRNA species."
      Kumar A. , Raphael C. , Adesnik M.
      J. Biol. Chem.258:11280-11284(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 281-491
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    7. 7.
      "Gene conversion in a cytochrome P-450 gene family."
      Atchison M.L. , Adesnik M.
      Proc. Natl. Acad. Sci. U.S.A.83:2300-2304(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 323-431
    8. 8.
      "Antibodies targeted against hypervariable and constant regions of cytochromes P450IIB1 and P450IIB2."
      Oesch F. , Waxman D.J. , Morrissey J.J. , Honscha W. , Kissel W. , Friedberg T.
      Arch. Biochem. Biophys.270:23-32(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 329-380 AND 402-423
    9. 9.
      "Segmental homologies in the coding and 3' non-coding sequences of rat liver cytochrome P-450e and P-450b cDNAs and cytochrome P-450e-like genes."
      Affolter M. , Anderson A.
      Biochem. Biophys. Res. Commun.118:655-662(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 385-491
    10. 10.
      "A mutant rat strain deficient in induction of a phenobarbital-inducible form of cytochrome P-450 in liver microsomes."
      Hashimoto T. , Matsumoto T. , Nishizawa M. , Kawabata S. , Morohashi K. , Handa S. , Omura T.
      J. Biochem.103:487-492(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-20
    11. 11.
      "Effect of nutritional imbalances on cytochrome P-450 isozymes in rat liver."
      Amelizad Z. , Narbonne J.F. , Wolf C.R. , Robertson L.W. , Oesch F.
      Biochem. Pharmacol.37:3245-3249(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-20
      tissue: Liver.
    12. 12.
      "Phosphorylation of hepatic phenobarbital-inducible cytochrome P-450."
      Pyerin W. , Taniguchi H.
      EMBO J.8:3003-3010(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-128
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