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Index > Protein center > Cyp2c6(Gene name) > Rat
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  • Cyp2c6 (Gene name),
  • Cytochrome P450 2C6 (Protein name ),  CP2C6_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Cyp2c6(Cyp2c-6);
    Protein name:
    Cytochrome P450 2C6;
    Alternative:
    Cytochrome P450 PB1;CYPIIC6;PTF2;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
    Subcellular Location:
    Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    490
    Sequence:
    50:
    MDLVMLLVLT | LTCLILLSIW | RQSSGRGKLP | PGPIPLPIIG | NIFQLNVKNI | 
    100:
    TQSLTSFSKV | YGPVFTLYFG | TKPTVILHGY | EAVKEALIDH | GEEFAERGSF | 
    150:
    PVAEKINKDL | GIVFSHGNRW | KEIRRFTLTT | LRNLGMGKRN | IEDRVQEEAR | 
    200:
    CLVEELRKTN | GSPCDPTFIL | GCAPCNVICS | IIFQNRFDYK | DQDFLNLMEK | 
    250:
    LNENMKILSS | PWTQFCSFFP | VLIDYCPGSH | TTLAKNVYHI | RNYLLKKIKE | 
    300:
    HQESLDVTNP | RDFIDYYLIK | WKQENHNPHS | EFTLENLSIT | VTDLFGAGTE | 
    350:
    TTSTTLRYAL | LLLLKCPEVT | AKVQEEIDRV | VGKHRSPCMQ | DRSRMPYTDA | 
    400:
    HDHEVQRFID | LIPTNLPHAV | TCDIKFRNYL | IPKGTTIITS | LSSVLHDSKE | 
    450:
    FPDPEIFDPG | HFLDGNGKFK | KSDYFMPFSA | GKRMCAGEGL | ARMELFLFLT | 
    490:
    TILQNFKLKS | VLHPKDIDTT | PVFNGFASLP | PFYELCFIPL | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Cytochrome P450 2C6
    CLIA Kit for Rat Cytochrome P450 2C6
    Polyclonal Antibody for Rat Cytochrome P450 2C6
    Monoclonal Antibody for Rat Cytochrome P450 2C6
    Protein for Rat Cytochrome P450 2C6

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Complementary DNA cloning of cytochrome P-450s related to P-450(M-1) from the complementary DNA library of female rat livers. Predicted primary structures for P-450f, PB-1, and PB-1-related protein with a bizarre replacement block and their mode of transcriptional expression."
      Kimura H. , Yoshioka H. , Sogawa K. , Sakai Y. , Fujii-Kuriyama Y.
      J. Biol. Chem.263:701-707(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
      tissue: Liver.
    2. 2.
      "Sequence of two related P-450 mRNAs transcriptionally increased during rat development. An R.dre.1 sequence occupies the complete 3' untranslated region of a liver mRNA."
      Gonzalez F.J. , Kimura S. , Song B.-J. , Pastewka J. , Gelboin H.V. , Hardwick J.P.
      J. Biol. Chem.261:10667-10672(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 6-490
    3. 3.
      "Isolation and characterization of cDNA clones for cytochromes P-450 immunochemically related to rat hepatic P-450 form PB-1."
      Friedberg T. , Waxman D.J. , Atchison M. , Kumar A. , Haaparanta T. , Raphael C. , Adesnik M.
      Biochemistry25:7975-7983(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 132-267
    4. 4.
      "Sequence of the 5' end of the developmentally regulated rat P450 PB1 (P450IIC6) gene."
      Umeno M. , Matsunaga E. , Morris S. , Gelboin H.V. , Gonzalez F.J.
      Nucleic Acids Res.16:6249-6249(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-56
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